Öz
Amaç: Bu çalışmada üriner sistem ultrasonografisi ile saptanan
böbrek anomalisi bulunan çocukların klinik ve demografik özelliklerinin
değerlendirilmesi amaçlanmıştır.
Materyal ve
Metot: Hastanemizde ultrasonografi ile üriner
sistem anomalisi saptanan ve bir yıllık izleminde ileri incelemeler yapılmış
olan çocukların tıbbi kayıtları retrospektif olarak incelendi.
Bulgular: Çalışmaya yaşları 0-17 yaş arasında, 179’u (%55.1) erkek
toplam 325 hasta alındı. En sık gözlenen üriner sistem anomalisi 103 (%31.7)
hastada saptanan üretero-pelvik darlık idi. Diğer tespit edilen anomaliler
hastaların 82’sinde (%25.2) vezikoüreteral reflü, 33’ünde (%10.2) renal
hipoplazi, 30’unda (%9.2) çift toplayıcı sistem, 18’inde (%5.5) posterior üretral
valv, 14’ünde (%4.3) üretero-vezikal darlık, 13’ünde (%4.0) renal agenezi,
13’ünde (%4.0) ektopik böbrek, 11’inde (%3.4) at nalı böbrek ve 8’inde (%2.5)
multikistik displastik böbrek olarak belirlendi. Beş hastada böbrek yetmezliği
ve 10 hastada hipertansiyon mevcuttu.
Sonuç: Üriner sistem anomalisi saptanan çocukların gelişebilecek
komplikasyonların belirlenmesi, renal hasarın saptanması ve eşlik eden ek
anormalliklerin değerlendirilmesi açısından yakından izlemleri gerekmektedir.
Anahtar Kelimeler
Çocuk Üriner sistem anomalisi Renal hasar Vezikoüreteral reflü
Kaynakça
- 1. Riccabona M. Imaging of the neonatal genito-urinary tract. Eur J Radiol. 2006 Nov;60(2):187-98. Epub 2006 Sep 7. PMID: 16959460
- 2. Kuhn JP, Slovis TL, Haller JO (eds). Caffey's Pediatric Diagnostic Imaging, 10th ed., vol. 2, Philadelphia, Mosby, 2004, p 2365
- 3. Rosenblum ND, Salomon R. Disorders of kidney formation. In: Geary DF, Schaefer F (eds). Comprehensive Pediatric Nephrology. Mosby-Elsevier, Philadelphia, 2008; 132-141.
- 4. Yosypiv IV. Congenital anomalies of the kidney and urinary tract: a genetic disorder? Int J Nephrol. 2012;2012:909083. doi: 10.1155/2012/909083. Epub 2012 May 20. PMID: 22685656
- 5. Keller G, Zimmer G, Mall G, Ritz E, Amann K. Nephron number in patients with primary hypertension. N Engl J Med 2003; 348: 101-8. PMID: 12918529
- 6. Fernbach SK, Feinstein KA, Schmidt MB. Pediatric voiding cystourethrography: a pictorial guide. Radiographics. 2000 Jan-Feb;20(1):155-68; discussion 168-71. Review. PMID: 10682779 DOI: 10.1148/radiographics.20.1.g00ja12155
- 7. Morris RK, Kilby MD. Congenital urinary tract obstruction. Best Pract Res Clin Obstet Gynaecol. 2008;22:97–122. PMID: 17904905
- 8. Şimşek F, Tinay İ. Çocuklarda üreteropelvik bileşke obstrüksiyonları. Klinik Gelişim 2008;21:24-27.].
- 9. Becker AM. Postnatal evaluation of infants with an abnormal antenatal renal sonogram. Curr Opin Pediatr 2009;21:207-213]. PMID: 19663038
- 10. Yürük Yıldırım ZN, Congenital Malformations Of Kidney. J Child. 2013; 13(4): 141-146. doi:10.5222/j.child. 2013.141.
- 11. Doğan ÇS, Torun-Bayram M, Aybar MD. Unilateral multicystic dysplastic kidney in children. Turk J Pediatr. 2014 Jan-Feb;56(1):75-9.). PMID: 24827951
- 12. Kaneko K, Suzuki Y, Fukuda Y, Yabuta K, Miyano T. Abnormal contralateral kidney in unilateral multicystic dysplastic kidney disease. Pediatr Radiol 1995;25:275-277. PMID: 7567236
- 13. Elmaci AM, Akın F. Konjenital böbrek ve üriner kanal anomalisi bulunan çocukların klinik ve demografik özellikleri. Dicle Medical Journal 2014; 41 (2): 309-312. doi: 10.5798/diclemedj.0921.2014.02.0422.
- 14. Guarino N, Tadini B, Camardi P, Silvestro L, Lace R, Bianchi M. The incidence of associated urological abnormalities in children with renal ectopia. J Urol 2004;172:1757-9. http://dx.doi.org/10.1097/01.ju.0000138376.93343.74. PMID: 15371807
- 15. Calisti A, Perrotta ML, Oriolo L, Ingianna D, Miele V. The risk of associated urological abnormalities in children with pre and postnatal occasional diagnosis of solitary, small or ectopic kidney: is a complete urological screening always necessary? World J Urol. 2008 Jun;26(3):281-4. doi: 10.1007/s00345-008-0249-0. Epub 2008 Mar 29. PMID: 18373095
- 16. Farrugia MK. Fetal bladder outlet obstruction: Embryopathology, in utero intervention and outcome. J Pediatr Urol. 2016 Oct; 12(5):296-303. doi: 10.1016/j.jpurol.2016.05.047. PMID: 27570093
- 17. Grigoris C, Kousidis. Posterior Urethral Valve; Essential in Pediatric Urology; 2012; 115-124). Research Signpost 37/661 (2), Fort P.O. Trivandrum-695 023 Kerala, India
- 18. Renjen P1, Bellah R, Hellinger JC, Darge K. Advances in uroradiologic imaging in children. Radiol Clin North Am. 2012 Mar;50(2):207-18 doi: 10.1016/j.rcl.2012.02.003. PMID: 22498439
- 19. Nakanishi K, Yoshikawa N. Genetic disorders of human congenital anomalies of the kidney and urinary tract (CAKUT). Pediatr Int 2003; 45: 610–616). PMID: 14521546
Öz
Background:
The aim of this study was to evaluate the clinical and demographic
characteristics of children with renal anomaly detected by urinary system
ultrasonography.
Methods: The medical
records of children with urinary system anomalies detected by ultrasonography
in our hospital and who underwent further investigations in one year follow-up
were examined retrospectively.
Results: A total of 325
patients were included in the study, the ages of between 0-17 years, 179
(55.1%) of them males. The most common urinary system anomaly was
uretero-pelvic junction obstruction in 103 (31.7%) patients. Other detected
anomalies were vesicoureteral reflux in 82 (25.2%) patients, renal hypoplasia
in 33 (10.2%), double collecting system in 30 (9.2%), posterior urethral valve
in 18 (5.5%), in 14 ( 4.3%) uretero-vesical junction obstruction, 13 (4.0%)
renal agenesis, 13 (4.0%) ectopic kidney, 11 (3.4%) horseshoe kidney, and 8
(2.5%) as multicystic dysplastic kidney determined. Five patients had renal
failure and 10 patients had hypertension.
Conclusion:
It is necessary to follow up closely to determine the complications that may
occur in children with urinary tract anomalies, to detect renal damage and to
evaluate the additional abnormalities.
Keywords:
Child, Urinary tract anomaly, Renal damage, Vesicoureteral reflux.
Anahtar Kelimeler
Child Urinary tract anomaly Renal damage Vesicoureteral reflux
Kaynakça
- 1. Riccabona M. Imaging of the neonatal genito-urinary tract. Eur J Radiol. 2006 Nov;60(2):187-98. Epub 2006 Sep 7. PMID: 16959460
- 2. Kuhn JP, Slovis TL, Haller JO (eds). Caffey's Pediatric Diagnostic Imaging, 10th ed., vol. 2, Philadelphia, Mosby, 2004, p 2365
- 3. Rosenblum ND, Salomon R. Disorders of kidney formation. In: Geary DF, Schaefer F (eds). Comprehensive Pediatric Nephrology. Mosby-Elsevier, Philadelphia, 2008; 132-141.
- 4. Yosypiv IV. Congenital anomalies of the kidney and urinary tract: a genetic disorder? Int J Nephrol. 2012;2012:909083. doi: 10.1155/2012/909083. Epub 2012 May 20. PMID: 22685656
- 5. Keller G, Zimmer G, Mall G, Ritz E, Amann K. Nephron number in patients with primary hypertension. N Engl J Med 2003; 348: 101-8. PMID: 12918529
- 6. Fernbach SK, Feinstein KA, Schmidt MB. Pediatric voiding cystourethrography: a pictorial guide. Radiographics. 2000 Jan-Feb;20(1):155-68; discussion 168-71. Review. PMID: 10682779 DOI: 10.1148/radiographics.20.1.g00ja12155
- 7. Morris RK, Kilby MD. Congenital urinary tract obstruction. Best Pract Res Clin Obstet Gynaecol. 2008;22:97–122. PMID: 17904905
- 8. Şimşek F, Tinay İ. Çocuklarda üreteropelvik bileşke obstrüksiyonları. Klinik Gelişim 2008;21:24-27.].
- 9. Becker AM. Postnatal evaluation of infants with an abnormal antenatal renal sonogram. Curr Opin Pediatr 2009;21:207-213]. PMID: 19663038
- 10. Yürük Yıldırım ZN, Congenital Malformations Of Kidney. J Child. 2013; 13(4): 141-146. doi:10.5222/j.child. 2013.141.
- 11. Doğan ÇS, Torun-Bayram M, Aybar MD. Unilateral multicystic dysplastic kidney in children. Turk J Pediatr. 2014 Jan-Feb;56(1):75-9.). PMID: 24827951
- 12. Kaneko K, Suzuki Y, Fukuda Y, Yabuta K, Miyano T. Abnormal contralateral kidney in unilateral multicystic dysplastic kidney disease. Pediatr Radiol 1995;25:275-277. PMID: 7567236
- 13. Elmaci AM, Akın F. Konjenital böbrek ve üriner kanal anomalisi bulunan çocukların klinik ve demografik özellikleri. Dicle Medical Journal 2014; 41 (2): 309-312. doi: 10.5798/diclemedj.0921.2014.02.0422.
- 14. Guarino N, Tadini B, Camardi P, Silvestro L, Lace R, Bianchi M. The incidence of associated urological abnormalities in children with renal ectopia. J Urol 2004;172:1757-9. http://dx.doi.org/10.1097/01.ju.0000138376.93343.74. PMID: 15371807
- 15. Calisti A, Perrotta ML, Oriolo L, Ingianna D, Miele V. The risk of associated urological abnormalities in children with pre and postnatal occasional diagnosis of solitary, small or ectopic kidney: is a complete urological screening always necessary? World J Urol. 2008 Jun;26(3):281-4. doi: 10.1007/s00345-008-0249-0. Epub 2008 Mar 29. PMID: 18373095
- 16. Farrugia MK. Fetal bladder outlet obstruction: Embryopathology, in utero intervention and outcome. J Pediatr Urol. 2016 Oct; 12(5):296-303. doi: 10.1016/j.jpurol.2016.05.047. PMID: 27570093
- 17. Grigoris C, Kousidis. Posterior Urethral Valve; Essential in Pediatric Urology; 2012; 115-124). Research Signpost 37/661 (2), Fort P.O. Trivandrum-695 023 Kerala, India
- 18. Renjen P1, Bellah R, Hellinger JC, Darge K. Advances in uroradiologic imaging in children. Radiol Clin North Am. 2012 Mar;50(2):207-18 doi: 10.1016/j.rcl.2012.02.003. PMID: 22498439
- 19. Nakanishi K, Yoshikawa N. Genetic disorders of human congenital anomalies of the kidney and urinary tract (CAKUT). Pediatr Int 2003; 45: 610–616). PMID: 14521546
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Konular | Klinik Tıp Bilimleri |
| Bölüm | Araştırma Makalesi |
| Yazarlar | |
| Yayımlanma Tarihi | 29 Ağustos 2019 |
| Gönderilme Tarihi | 21 Ocak 2019 |
| Kabul Tarihi | 10 Mayıs 2019 |
| Yayımlandığı Sayı | Yıl 2019 Cilt: 16 Sayı: 2 |
Harran Üniversitesi Tıp Fakültesi Dergisi / Journal of Harran University Medical Faculty