Introduction
Hyperimmunoglobulin E syndrome (HIES) is a rare genetic based multi-system disorder. It is characterized by high serum
levels of IgE, pulmonary and recurrent skin infection except for these conditions abnormalities of the dentition, bones and
connective tissue could be seen. The etiology of HIES is considered to be dominant-negative alterations in signal transducer
and activator of transcription 3 (STAT3). STAT3 is integral to signal transduction for multiple cytokines. STAT3 is well expressed
across tissue types.
Case Report
In this paper, we report a 7-year-old boy with HIES and a rare clinical manifestation regarding radicular cyst which is related
to the deciduous tooth.
Conclusion
Chronic usage of antibiotics in the HIES patients can cause that sup-pressed serious lesion so that radicular cysts may be
missed. Therefore, dentists should be alert on clinical and radiologic examination.
Primary Language | English |
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Subjects | Facial Plastic Surgery |
Journal Section | Case Reports |
Authors | |
Early Pub Date | December 20, 2023 |
Publication Date | December 30, 2022 |
Published in Issue | Year 2022 Volume: 1 Issue: 1 |
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