Nazal septum deviasyon tipinin sistemik inflamasyon indeksi ve inflamasyonun kan belirteçleri üzerine etkisi

Year 2023, Volume: 6 Issue: 5, 1069 - 1073, 28.09.2023

Süheyla Kandemir Gözde Pamuk

https://doi.org/10.32322/jhsm.1343255

Abstract

Amaç: Bu çalışmanın amacı, nazal septum deviasyonu (NSD) olan hastalarda inflamasyonun kan belirteçlerindeki değişiklikleri ve sistemik immün inflamatuar indeksi belirlemekti. Ek bir amaç da septum deviasyon tipine göre bulgularda anlamlı bir fark olup olmadığını belirlemekti.
Gereç ve Yöntemler: Bu retrospektif çalışmaya fizik muayene ve BT (NSD grubu) ile NSD tanısı konan 321 hasta ve 101 sağlıklı kontrol dahil edildi. Standart tam kan sayımı yapıldı. Ana kan parametreleri ve ortalama trombosit hacmi (MPV), nötrofil-lenfosit oranı (NLR), trombosit-lenfosit oranı (PLR) ve sistemik immün inflamatuar indeks (SII) kaydedildi. NSD, Dreher sınıflamasına göre 3 tip olarak sınıflandırıldı ve tipler kendi aralarında ve kontrol grubuyla karşılaştırıldı.
Bulgular: Hemoglobin seviyesi, trombosit ve nötrofil sayıları NSD grubunda kontrol grubuna göre anlamlı derecede yüksekti (her biri için P < 0.001). MPV, NLR, PLR ve SII de NSD grubunda anlamlı olarak daha yüksekti (her biri için P < 0.001). Septum deviasyonu derecesi arttıkça enflamasyonun tüm kan belirteçlerinde önemli bir artış oldu (her biri için P < 0.001).
Sonuç: İnflamasyonun kan belirteçleri, NSD'li hastalarda önemli ölçüde yüksektir. Bulgular, SII'nin NSD'li hastalarda inflamasyonu ölçmek için yararlı ve ucuz bir yöntem olduğunu göstermektedir. Septum deviasyonunun derecesi inflamasyonun derecesini etkileyebilir.

Keywords

Nazal Septum, Nazal Obstrüksiyon, Ortalama Trombosit Hacmi

Supporting Institution

Yok

Project Number

Yok

The effect of nasal septum deviation type on the systemic inflammatory index and blood markers of inflammation

Abstract

Aims: The aim of this study was to identify the changes in blood markers of inflammation and the systemic immune inflammatory index in patients with nasal septum deviation (NSD). An additional aim was to determine if there was a significant difference in the findings according to septum deviation type.
Methods: This retrospective study included 321 patients diagnosed with NSD via physical examination and CT (NSD group), and 101 healthy controls. Standard complete blood count was performed. Main blood parameters and mean platelet volume (MPV), the neutrophil-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR), and the systemic immune inflammatory index (SII) were recorded. NSD was classified as 3 types according to Dreher classification, and the types were compared to each other and the control group.
Results: The hemoglobin level, and platelet and neutrophil counts were significantly higher in the NSD group than in the control group (P<0.001 for each). The MPV, NLR, PLR, and SII were also significantly higher in the NSD group (P<0.001 for each). There was a significant increase in all blood markers of inflammation as the degree of septum deviation increased (P<0.001 for each).
Conclusion: Blood markers of inflammation are significantly elevated in patients with NSD. The SII value can indicate an inflammatory condition in these patients. The degree of septum deviation can affect the degree of inflammation.

Keywords

Nasal septum, nasal obstruction, mean platelet volume

Project Number

Yok

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