Systematic Reviews and Meta Analysis
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Year 2024, Issue: 1, 9 - 24, 09.03.2024

Abstract

References

  • Referans1. López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. Jun 6 2013;153(6):1194-217. doi:10.1016/j.cell.2013.05.039
  • Referans2. Depp CA, Jeste DV. Definitions and predictors of successful aging: a comprehensive review of larger quantitative studies. Am J Geriatr Psychiatry. Jan 2006;14(1):6-20. doi:10.1097/01.JGP.0000192501.03069.bc
  • Referans13. Rowe JW, Kahn RL. Successful aging. Gerontologist. Aug 1997;37(4):433-40. doi:10.1093/geront/37.4.433
  • Referans4. Urtamo A, Jyväkorpi SK, Strandberg TE. Definitions of successful ageing: a brief review of a multidimensional concept. Acta Biomed. May 23 2019;90(2):359-363. doi:10.23750/abm.v90i2.8376
  • Referans5. Jabès A, Klencklen G, Ruggeri P, Antonietti JP, Banta Lavenex P, Lavenex P. Age-Related Differences in Resting-State EEG and Allocentric Spatial Working Memory Performance. Front Aging Neurosci. 2021;13:704362. doi:10.3389/fnagi.2021.704362
  • Referans6. Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease. Circulation. Jan 7 2003;107(1):139-46. doi:10.1161/01.cir.0000048892.83521.58
  • Referans7. Veldhuis JD. Aging and hormones of the hypothalamo-pituitary axis: gonadotropic axis in men and somatotropic axes in men and women. Ageing Res Rev. Jul 2008;7(3):189-208. doi:10.1016/j.arr.2007.12.005
  • Referans8. Olshansky SJ, Goldman DP, Zheng Y, Rowe JW. Aging in America in the twenty-first century: demographic forecasts from the MacArthur Foundation Research Network on an Aging Society. Milbank Q. Dec 2009;87(4):842-62. doi:10.1111/j.1468-0009.2009.00581.x
  • Referans9. Brooks-Wilson AR. Genetics of healthy aging and longevity. Hum Genet. Dec 2013;132(12):1323-38. doi:10.1007/s00439-013-1342-z
  • Referans10. Garrett M. The Handbook of Aging and Cognition by F. I. M. Craik and T. A. Salthouse, eds. Activities, Adaptation & Aging. 11/30 2009;33:267-268. doi:10.1080/01924780903295796
  • Referans11. Mather M, Harley CW. The Locus Coeruleus: Essential for Maintaining Cognitive Function and the Aging Brain. Trends Cogn Sci. Mar 2016;20(3):214-226. doi:10.1016/j.tics.2016.01.001
  • Referans12. Arem H, Moore SC, Patel A, et al. Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship. JAMA internal medicine. 2015;175(6):959-967.
  • Referans13. Biagi E, Franceschi C, Rampelli S, et al. Gut Microbiota and Extreme Longevity. Curr Biol. Jun 6 2016;26(11):1480-5. doi:10.1016/j.cub.2016.04.016
  • Referans14. Brancaccio M, Mennitti C, Cesaro A, et al. The Biological Role of Vitamins in Athletes' Muscle, Heart and Microbiota. Int J Environ Res Public Health. Jan 23 2022;19(3)doi:10.3390/ijerph19031249
  • Referans15. Darooghegi Mofrad M, Naghshi S, Lotfi K, et al. Egg and Dietary Cholesterol Intake and Risk of All-Cause, Cardiovascular, and Cancer Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies. Front Nutr. 2022;9:878979. doi:10.3389/fnut.2022.878979
  • Referans16. Dzierzewski JM, Dautovich N, Ravyts S. Sleep and Cognition in Older Adults. Sleep Med Clin. Mar 2018;13(1):93-106. doi:10.1016/j.jsmc.2017.09.009
  • Referans17. Jones MJ, Goodman SJ, Kobor MS. DNA methylation and healthy human aging. Aging Cell. Dec 2015;14(6):924-32. doi:10.1111/acel.12349
  • Referans18. Kawagoe T. Overview of (f)MRI Studies of Cognitive Aging for Non-Experts: Looking through the Lens of Neuroimaging. Life (Basel). Mar 12 2022;12(3)doi:10.3390/life12030416
  • Referans19. Kendig H, Browning CJ, Thomas SA, Wells Y. Health, lifestyle, and gender influences on aging well: an Australian longitudinal analysis to guide health promotion. Front Public Health. 2014;2:70. doi:10.3389/fpubh.2014.00070
  • Referans20. Kennedy BK, Berger SL, Brunet A, et al. Geroscience: linking aging to chronic disease. Cell. Nov 6 2014;159(4):709-13. doi:10.1016/j.cell.2014.10.039
  • Referans21. Ravyts SG, Dzierzewski JM. Sleep and Healthy Aging: A Systematic Review and Path Forward. Clin Gerontol. Apr 21 2022:1-13. doi:10.1080/07317115.2022.2064789
  • Referans22. Ruiz-Narváez EA, Baylin A, Azofeifa J, Leal A, Rosero-Bixby L. Diet and Leukocyte Telomere Length in a Population with Extended Longevity: The Costa Rican Longevity and Healthy Aging Study (CRELES). Nutrients. Jul 28 2021;13(8)doi:10.3390/nu13082585
  • Referans23 Spencer BE, Jennings RG, Brewer JB. Combined Biomarker Prognosis of Mild Cognitive Impairment: An 11-Year Follow-Up Study in the Alzheimer's Disease Neuroimaging Initiative. J Alzheimers Dis. 2019;68(4):1549-1559. doi:10.3233/jad-181243
  • Referans24 Li Y, Cui M, Pang Y, et al. Association of physical activity with socio-economic status and chronic disease in older adults in China: cross-sectional findings from the survey of CLASS 2020 after the outbreak of COVID-19. BMC Public Health. 2024/01/02 2024;24(1):37. doi:10.1186/s12889-023-17492-9

Factors affecting healthy aging and its interconnected pathways

Year 2024, Issue: 1, 9 - 24, 09.03.2024

Abstract

The process of aging is influenced by factors across different aspects of life including biology, lifestyle, and the surrounding environment. As the global population continues to age it is crucial to understand the complexities involved in maintaining the health and quality of life of adults. This article offers an overview of the dimensions of aging by examining the key factors and demonstrating how they are interconnected in shaping the aging process. Biological factors play a role at molecular and systemic levels. Lifestyle choices also have an impact with regular physical activity, a balanced diet, sufficient sleep, and cognitive engagement all contributing to overall well-being.

Social support networks, community resources and access to healthcare services are environmental factors that also influence healthy aging trajectories. In addition, socioeconomic circumstances contribute to disparities in aging outcomes with individuals from poorer backgrounds often facing greater challenges in accessing resources and healthcare services. Genetic predisposition can play a role in determining how well we are with certain genes and molecular pathways associated with age related diseases that can affect longevity.

In order to comprehensively explore the literature on aging, this study employed the methodological approach of a scoping review to identify topics and evidence types, and also a rapid review to systematically map current knowledge. This combination provides a focus on qualitative summaries rather than exhaustive analysis and enabled a systematic search for relevant papers while ensuring rigorous screening processes for categorizing and synthesizing the findings. It involved searching the PubMed database by scanning titles and abstracts for relevance and then organizing information based on the dominant themes. A qualitative analysis of the evidence was then carried out, related to the concept of healthy aging, while also identifying gaps in the research.

The result is an overview of the evidence surrounding aging and areas that require investigation. To summarize, this innovative approach using scoping and rapid review methodologies enabled a systematic mapping of current knowledge about aging. By examining these factors, and understanding their interconnectedness, approaches can be developed that will be effective in helping to promote healthy aging and thereby enhance the quality of life for older adults. This article aims to provide insights into the influencers of the aging process while also highlighting potential avenues for future research and interventions.
Keywords: Healthy aging, lifestyle choices, environmental factors

References

  • Referans1. López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. Jun 6 2013;153(6):1194-217. doi:10.1016/j.cell.2013.05.039
  • Referans2. Depp CA, Jeste DV. Definitions and predictors of successful aging: a comprehensive review of larger quantitative studies. Am J Geriatr Psychiatry. Jan 2006;14(1):6-20. doi:10.1097/01.JGP.0000192501.03069.bc
  • Referans13. Rowe JW, Kahn RL. Successful aging. Gerontologist. Aug 1997;37(4):433-40. doi:10.1093/geront/37.4.433
  • Referans4. Urtamo A, Jyväkorpi SK, Strandberg TE. Definitions of successful ageing: a brief review of a multidimensional concept. Acta Biomed. May 23 2019;90(2):359-363. doi:10.23750/abm.v90i2.8376
  • Referans5. Jabès A, Klencklen G, Ruggeri P, Antonietti JP, Banta Lavenex P, Lavenex P. Age-Related Differences in Resting-State EEG and Allocentric Spatial Working Memory Performance. Front Aging Neurosci. 2021;13:704362. doi:10.3389/fnagi.2021.704362
  • Referans6. Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease. Circulation. Jan 7 2003;107(1):139-46. doi:10.1161/01.cir.0000048892.83521.58
  • Referans7. Veldhuis JD. Aging and hormones of the hypothalamo-pituitary axis: gonadotropic axis in men and somatotropic axes in men and women. Ageing Res Rev. Jul 2008;7(3):189-208. doi:10.1016/j.arr.2007.12.005
  • Referans8. Olshansky SJ, Goldman DP, Zheng Y, Rowe JW. Aging in America in the twenty-first century: demographic forecasts from the MacArthur Foundation Research Network on an Aging Society. Milbank Q. Dec 2009;87(4):842-62. doi:10.1111/j.1468-0009.2009.00581.x
  • Referans9. Brooks-Wilson AR. Genetics of healthy aging and longevity. Hum Genet. Dec 2013;132(12):1323-38. doi:10.1007/s00439-013-1342-z
  • Referans10. Garrett M. The Handbook of Aging and Cognition by F. I. M. Craik and T. A. Salthouse, eds. Activities, Adaptation & Aging. 11/30 2009;33:267-268. doi:10.1080/01924780903295796
  • Referans11. Mather M, Harley CW. The Locus Coeruleus: Essential for Maintaining Cognitive Function and the Aging Brain. Trends Cogn Sci. Mar 2016;20(3):214-226. doi:10.1016/j.tics.2016.01.001
  • Referans12. Arem H, Moore SC, Patel A, et al. Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship. JAMA internal medicine. 2015;175(6):959-967.
  • Referans13. Biagi E, Franceschi C, Rampelli S, et al. Gut Microbiota and Extreme Longevity. Curr Biol. Jun 6 2016;26(11):1480-5. doi:10.1016/j.cub.2016.04.016
  • Referans14. Brancaccio M, Mennitti C, Cesaro A, et al. The Biological Role of Vitamins in Athletes' Muscle, Heart and Microbiota. Int J Environ Res Public Health. Jan 23 2022;19(3)doi:10.3390/ijerph19031249
  • Referans15. Darooghegi Mofrad M, Naghshi S, Lotfi K, et al. Egg and Dietary Cholesterol Intake and Risk of All-Cause, Cardiovascular, and Cancer Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies. Front Nutr. 2022;9:878979. doi:10.3389/fnut.2022.878979
  • Referans16. Dzierzewski JM, Dautovich N, Ravyts S. Sleep and Cognition in Older Adults. Sleep Med Clin. Mar 2018;13(1):93-106. doi:10.1016/j.jsmc.2017.09.009
  • Referans17. Jones MJ, Goodman SJ, Kobor MS. DNA methylation and healthy human aging. Aging Cell. Dec 2015;14(6):924-32. doi:10.1111/acel.12349
  • Referans18. Kawagoe T. Overview of (f)MRI Studies of Cognitive Aging for Non-Experts: Looking through the Lens of Neuroimaging. Life (Basel). Mar 12 2022;12(3)doi:10.3390/life12030416
  • Referans19. Kendig H, Browning CJ, Thomas SA, Wells Y. Health, lifestyle, and gender influences on aging well: an Australian longitudinal analysis to guide health promotion. Front Public Health. 2014;2:70. doi:10.3389/fpubh.2014.00070
  • Referans20. Kennedy BK, Berger SL, Brunet A, et al. Geroscience: linking aging to chronic disease. Cell. Nov 6 2014;159(4):709-13. doi:10.1016/j.cell.2014.10.039
  • Referans21. Ravyts SG, Dzierzewski JM. Sleep and Healthy Aging: A Systematic Review and Path Forward. Clin Gerontol. Apr 21 2022:1-13. doi:10.1080/07317115.2022.2064789
  • Referans22. Ruiz-Narváez EA, Baylin A, Azofeifa J, Leal A, Rosero-Bixby L. Diet and Leukocyte Telomere Length in a Population with Extended Longevity: The Costa Rican Longevity and Healthy Aging Study (CRELES). Nutrients. Jul 28 2021;13(8)doi:10.3390/nu13082585
  • Referans23 Spencer BE, Jennings RG, Brewer JB. Combined Biomarker Prognosis of Mild Cognitive Impairment: An 11-Year Follow-Up Study in the Alzheimer's Disease Neuroimaging Initiative. J Alzheimers Dis. 2019;68(4):1549-1559. doi:10.3233/jad-181243
  • Referans24 Li Y, Cui M, Pang Y, et al. Association of physical activity with socio-economic status and chronic disease in older adults in China: cross-sectional findings from the survey of CLASS 2020 after the outbreak of COVID-19. BMC Public Health. 2024/01/02 2024;24(1):37. doi:10.1186/s12889-023-17492-9
There are 24 citations in total.

Details

Primary Language English
Subjects Health Promotion
Journal Section Reviews
Authors

Kwaku Mari Addo 0000-0003-0662-5450

Hafiz Khan 0000-0002-1817-3730

Publication Date March 9, 2024
Submission Date February 19, 2024
Acceptance Date March 7, 2024
Published in Issue Year 2024 Issue: 1

Cite

APA Addo, K. M., & Khan, H. (2024). Factors affecting healthy aging and its interconnected pathways. Turkish Journal of Healthy Aging Medicine(1), 9-24.