Parvovirus (PV) is a
single-stranded DNA virus with a non-enveloped nucleus having a size of
18-26nm. It comprise 60 structural proteins which are of two types. PV B19
transmits through respiratory droplets or blood transfusion but some nosocomial
infections also give a chance to PV B19 for causing an infection.
The study was particularly
conducted on Sickle Cell Anemia (SCA) patients and focuses on the determination
of parvovirus among Bahraini population by relying on their clinical status.
Three groups have been taken for the serological study of PV B19. Moreover, around
100 healthy blood donors were taken in which both the males and females were
included. However, samples were taken from the emergency unit of Salmania
Medical Complex (SMC) and Ibrahim Khalil Kano Center (IKKC).
It is a
cohort study based on total 250 people among which 150 were SCA patients, and
100 were healthy individuals. The findings reveal that approximately 40%
patients suffered from VOC whereas, only 20% were detected in SCA patients with
Non-Vaso-Occlusive Crises (NVOC). It was observed that the percentages were
relatively same in both the male and female groups i.e. 33.2%. The percentage
for the control group was 33.6 % in which 84 males and 16 females were
included.
Parvovirus is a pathogenic virus
and sometimes considered as life-threatening specifically for those individuals
who have SCA due to which a risk of transient aplastic crisis increases. This
virus is only associated with those patients who have some haematological
disorders such as haemolytic anaemia and erythro-cytopenia. It is observed that
just because of inappropriate features of testing the risk of PV B19 infection can increase. An
effective screening test must be performed in the future to reduce the risk of
PV B19 infection.
Konular | Mühendislik |
---|---|
Bölüm | Makaleler |
Yazarlar | |
Yayımlanma Tarihi | 9 Kasım 2017 |
Yayımlandığı Sayı | Yıl 2017Sayı: 1 |