Preparation of Sodium Carboxymethly Cellulose Hydrogels for Controlled Release of Copper Micronutrient

Yıl 2018, Sayı: 2, 25 - 34, 19.08.2018

Mehlika Pulat Gulen Oytun Akalin

Öz

In
this study, a series of nanoporous
sodium carboxymethyl cellulose (NaCMC) hydrogels were synthesized using FeCl₃
ionic-crosslinker by changing the amounts of the components. Hydrogel formation percentages of the samples were determined and the
highest value was obtained as 96% for the hydrogel containing the most amounts
of polymer and crosslinker. Swelling/degradation behaviors of the hydrogels
were studied by changing time, temperature and pH and it was determined that
the swelling percentages regularly
decreased with increasing the amounts of polymer and crossliker. S%
values were determined to be 102% for the least swollen hydrogel. In general, NaCMC hydrogels
much more swelled in basic medium than acidic medium. Releasing of copper micronutrient from NaCMC
hydrogels were investigated by Atomic Absorption Spectrometer
measurements.  Kinetic in vitro release
parameters, the release rate factor K and
the release exponent n of
micronutrients in hydrogel system were calculated. It can be concluded that the
produced hydrogel system having controllable release values is useful for
agricultural applications. 

Anahtar Kelimeler

Sodium carboxymethyl cellulose, Hydrogel, Micronutrient, Controlled-release

Kaynakça

• Akalin G.O., Pulat M. (2018). Preparation and Characterization of Nanoporous Sodium Carboxymethyl Cellulose Hydrogel Beads, Journal of Nanomaterials, Article ID 9676949, 12 pages. Barbucci, R., Magnani, A., and Consumi, M. (2000). Swelling behavior of carboxymethylcellulose hydrogels in relation to crosslinking, pH, and charge density,” Macromolecules, 33:20, 7475–7480. Chen K., Ku Y., Lin H., Yan T., Sheu D., Chen T., Lin F. (2005). Preparation and char¬acterization of pH-sensitive poly (N-vinyl 2-pyrrolidone/itaconic acid) copolymer hydrogels. Mat. Chem. Phys. 91, 484-489. El-Sherbiny I.M., Lins R.J., Abdel-Bary E.M., Harding D.R.K.(2005). Preparation, char¬acterization, swelling and in vitro drug release behaviour of poly(N-AG-chitosan) interpolymeric pH and therm.-responsive hydrogels. Europ. Polym. J. 41, 2584-2591. Pulat M., Akalın G.O. (2013). Preparation and characterization of gelatin hydrogel support for immobilization of C. Rugosa lipase. Artif. Cells Nanomed. Biotechnol. 41, 145-151. Pulat M., Akalın G.O, Demirkol Karahan N. (2014). Lipase release through semi-interpenetrating polymer network hydrogels based on chitosan, acrylamide, and citraconic acid. Artif. Cells Nanomed. Biotechnol. 42, 121-127. Pulat M., Asıl D. (2009). Fluconazole release through semi-ipn hydrogels based on chitosan, AA, and citraconic acid. J. Appl. Polym. Sci. 113, 2613-2619. Pulat M., Tan N., Onurdağ F.K. (2011). Swelling dynamics of IPN hydrogels including acrylamide-acrylic acid-chitosan and evaluation of their potential for controlled release of piperacillin-tazobactam. J. Appl. Polym. Sci. 120, 441-450. Pulat M. & Uğurlu N. (2016). Preparation and characterization of biodegradable gelatin-PAAm-based IPN hydrogels for controlled release of maleic acid to improve the solubility of phosphate fertilizers, Soft Materıals, , 14:4, 217–227. Pulat M., Yoltay N. (2016). Smart fertilizers: preparation and characterization of gelatin-based hydrogels for controlled release of MAP and AN fertilizers, Agrochimica, 60:4, 249-261. Rafaat A.I, Eid M., El-Arnaouty M.B. (2012). Radiation synthesis of superabsorbent CMC based hydrogels for agriculture applications. Nucl. Instr. Meth. Phys. Res. B, 283, 71-76. Trenkel M.E. (2007). Controlled release fertilizers: trends and technologies. Pharmaceutica. 5, 1-15