The association of carotid intima-media thickness with body mass index and cortisol level in fibromyalgia syndrome

Yıl 2019, Cilt: 5 Sayı: 1, 83 - 87, 04.01.2019

Tuba Tülay Koca Ayla Çimen

https://doi.org/10.18621/eurj.376343

Cited By: 3

Öz

Objectives: Patients with fibromyalgia
syndrome (FMS) may have the risk for atherosclerotic disease because of chronic
stress, disrupted neuroendocrine axis, high BMI and inflammation. This is study
aimed to research the stress and the stress-related diseases in patients with
FMS by measuring obesity, morning serum cortisol level, and carotid
intima-media thickness (CIMT), which is the early indicator of the
atherosclerosis.

Methods: This case-control study included 57 patients who were
diagnosed with FMS according to 2010 American
College of Rheumatology (ACR) Criteria
and visited the outpatient clinic in February 2016. As a control group, 36
healthy females who visited the outpatient clinic in the same month were
included. Carotid intima-media thickness and cortisol levels were analysed.

Results: The present study included 93 females between 15 and 79 years old. The mean
age of the 57 females with FMS and 37 healthy females was 44.5 ±
10.6 years and 47.9 ± 18.5 years, respectively (p = 0.260). The mean CIMT value of the
FMS and control groups was 0.64 ± 0.17 mm and 0.59 ± 0.16 mm, respectively (p = 0.170). The morning blood cortisol
level in the FMS and control groups was 7.8 ± 3.3 ng/dL and 8.7 ± 2.8 ng/dL,
respectively (p = 0.460). The CIMT
and morning blood cortisol level were not correlated in the FMS group.

Conclusion: According to the present study, CIMT value and
morning blood cortisol level were not found significantly different in FMS
group, and also were not  found
correlated with each other. 

Anahtar Kelimeler

Atherosclerosis, carotid intima-media thickness, fibromyalgia syndrome

Kaynakça

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