Evaluation of Antimicrobial Activity of Three Endemic Salvia Species Growing in Turkey

Yıl 2018, Cilt: 38 Sayı: 1, 4 - 10, 15.01.2018

Sevda Güzel Yusuf Özay Mahmut Ülger Ahmet Kahraman Gönül Aslan

Öz

The ethanol extracts obtained from the aerial parts of three Salvia species (S. hypargeia,

S. huberi and S. dichroantha) which are endemic to Turkey were tested for their antibacterial

and antifungal activities against two Gram (+) bacterial strains [Staphylococcus

aureus (ATCC 25925), Bacillus subtilis (ATCC 6633)]; three Gram (-) bacterial strains

[Escherichia coli (ATCC 25923), Acinetobacter baumannii (ATCC 02026), Aeromonas

hydrophila (ATCC 95080)] and Mycobacterium tuberculosis H37Rv, and three fungal

strains (Candida glabrata ATCC 90030, C. parapsilosis ATCC 22019, C. tropicalis

ATCC 750) by using the broth microdilution method. All tested plant extracts showed

significantly antibacterial activity against A. baumannii (ATCC 02026) (62.5 μg/mL

MIC value) when compared to reference drug Ampicillin (125 μg/mL MIC value).

The ethanolic extract of S. huberi was found the most effectiveness extract against M.

tuberculosis H37Rv with 0.97 μg/mL MIC value when compared to reference antimycobacterial

agents Isoniazid and Ethambutol (0.97 μg/mL and 1.95 μg/mL MIC values,

respectively).

Anahtar Kelimeler

Salvia species, antimicrobial activity, plant extract

Kaynakça

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