Synchronous Occurence of Extramedullary Plasmacytoma and Squamous Cell Carcinoma in the Larynx

Yıl 2015, Cilt: 1 Sayı: 2, 43 - 45, 16.05.2015

Fatma Senel Altan Kaya Hatice Karaman

Öz

Exramedullary plasmacytoma of the larynx is rare, especially when coexisted with squamous cell carcinoma. A 62-year-old male presented with history hoarseness and dyspnea. After laryngoscopic examination biopsy was performed epiglot and left ventricular band. The pathological examination revealed with the diagnosis of plasmacytoma and squamous cell carcinoma. The diagnosis of multiple myeloma was excluded as nonspesific results were obtained flow cytometry and peripheral blood smear. This case is the second repord of syncronous squamous cell carcinoma and extramedullary plasmacytoma of the larynx in the literature.

Anahtar Kelimeler

Extramedullary plasmacytoma; larynx; squamous cell carcinoma; synchronous

LARİNKSTE SKUAMÖZ HÜCRELİ KARSİNOM VE EKSTRAMEDÜLLER PLAZMASİTOM BİRLİKTELİĞİ

Öz

Larinksin ekstramedüller plazmasitomu az görülmekte olup, özellikle de skuamöz hücreli karsinom ile birlikteliği oldukça nadirdir. 62 yaşındaki
ses kısıklığı ve nefes darlığı şikayetleri ile başvuran erkek hastaya laringoskopi yapılıp epiglot ve sol band ventrikülden biyopsi alındı, patolojik
inceleme sonrası skuamöz hücreli karsinom ve plazmasitom tanısı aldı. Periferik yayma ve flow sitometri bulgularında özellik saptanmaması ile
multipl myelom ekarte edilerek ekstramedüller plazmasitom olarak değerlendirildi. Bu vaka literatürdeki larinkste ekstramedüller
plazmasitom ve skuamöz hücreli karsinom birlikteliği gösteren ikinci vakadır.

Anahtar Kelimeler

Ekstramedüller plazmasitom, larinks, skuamöz hücreli karsinom, senkron

Kaynakça

• Alexiou C, Kau RJ, Dietzfelbinger H, Kremer M, Spiess JC, Schratzenstaller B, et al. Extramedullary plasmacytoma: tumor occurrence and therapeutic concepts. Cancer. 1999; 85(11):2305-2314.
• Sulzner SE, Amdur RJ, Weider DJ. Extramedullary plasmacytoma of the head and neck. Am J Otolaryngol. 1998; 19(3):203-208.
• Strojan P. Extramedullary plasmacytoma of the larynx:a report of three Cases. Radiol Oncol. 2002; 36(3):225-254.
• Dimopoulos MA, Hamilos G. Solitary bone plasmacytoma and extramedullary plasmacytoma. Curr Treat Options Oncol. 2002; 3(3): 255-259.
• Jones AS, Morar P, Phillips DE, Field JK, Husband D, Helliwell TR. Second primary tumors in patients with head and neck squamous cell carcinoma. Cancer .1995; 75(6):1343-1353.
• Watanabe N, Inohara H, Akahani S, Yamamoto Y, Moriwaki K, Kubo T. Synchronous squamous cell carcinoma and malignant lymphoma in the head and neck region. Auris Nasus Larynx. 2007; 34(2):273-274.
• Zhang XL, Li DQ, Li JJ, Li SS, Yang XM. Synchronous occurrence of extramedullary plasmacytoma and squamous cell carcinoma in situ in the larynx: a case report. Chin J Cancer. 2010 ; 29(12):1029-1034.
• Saad R, Raab S, Liu Y, Pollice P, Silverman JF. Plasmacytoma of the larynx diagnosed by fine-needle aspiration cytology: a case report. Diagn Cytopathol. 2002; 24(6):408-411.
• Velez D, Hinojar-Gutierrez A, Nam-Cha S, Acevedo-Barbera A. Laryngeal plasmacytoma presenting as amyloid tumour: a case report. Eur Arch Otorhinolaryngol. 2007;264(8):959-961.