BibTex RIS Kaynak Göster

Çocuk Acil Servise Başvuran Nöroleptik Malign Sendromlu Bir Olgu Sunumu

Yıl 2015, Cilt: 6 Sayı: 1, 19 - 22, 01.01.2015

Öz

Giriş: Nöroleptik malign sendrom, antipsikotik ilaç kullanımına
bağlı gelişen nadir fakat hayatı tehdit eden bir klinik tablodur.
Yüksek ateş, kas rijiditesi ve bilinç kaybı ile acil servise başvuran
bir hastada dikkatli bir öykü alınmalı ve antipsikotik ilaç kullanım
öyküsü varsa nöroleptik malign sendrom öncelikle akla
getirilmelidir.
Olgu Sunumu: 14 yaşında erkek hasta, konuşamama, yutma
güçlüğü, kendinden geçme ve idrarını kaçırma şikayetleri ile
hastanemiz çocuk acil servisine başvurdu. Öyküde 100 mg etken
madde olan risperidon şişesini 10 günde bitirdiği öğrenildi.
Muayenesinde genel durumu orta, bilinç konfüydü. Laboratuvar
testleri normale yakındı. Hasta nöroleptik malign sendrom
tanısıyla yoğunbakım ünitesine çıkartıldı.
Sonuç: Nöroleptik malign sendrom, acil tanı konması ve hızlı
müdahale edilmesi gereken fatal seyirli bir durumdur. Yüksek
ateş, kas sertliği ve bilinç kaybıyla acil servise başvuran hastalarda
dikkatli bir anamnez alınmalı ve hastanın antipsikotik kullanım
öyküsü varsa mutlaka ön sıralarda akla getirilmesi gereken klinik
bir tablodur.

Kaynakça

  • Neuhut R, Lindenmayer JP, Silva R. Neuroleptic Malignant Syndrome in Children and Adolescents on Atypical Antipsychotic Medication: A Review. J Child Adolesc Psychopharmacol. 2009; 19 : 415-22. [CrossRef]
  • Rasimas JJ, Liebelt EL. Adverse Effects and Toxicity of the Atypical Antipsychotics: What is Important for the Pediatric Emergency Medicine Practitioner Clin Pediatr Emerg Med. 2012; 13: 300-10.
  • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Text Revision. Washington, DC, American Psychiatric Association, 2000.
  • Nierenberg D, Disch M, Manheimer E, Patterson J, Ross J, Sivestri G, et al. Facilitating prompt diagnosis and treatment of the neuroleptic malignant syndrome. Clin Pharmacol Ther 1991; 50: 580-6. [CrossRef]
  • Doğan N, Kürşad H, Erdem AF, Kızılkaya M. Nöroleptik Malin Sendromda Nadir Etyolojik Faktörler ve Klinik Seyir. AÜTD 2003; 35: 23-6.
  • Rasmussen KG. Risk factors for neuroleptic malignant syndrome. Am J Psychiatry 1998; 155: 1639-40. [CrossRef]
  • Steele D, Keltner NL, McGuiness TM. Are neuroleptic malignant syndrome and serotonin syndrome the same syndrome? Perspect Psychiatr Care 2011; 47: 58-62. [CrossRef]
  • Çakın Memik N, karakay I, Çoşkun A, Ağaoğlu B. Erken Ergenlikte Nöroleptik Malign Sendrom: Bir Olgu Sunumu. Çocuk ve Gençlik Ruh Sağlığı Dergisi 2006; 13: 124-9.
  • Star K, Lessa N, Almandil NB, Wilton L, Curran S, Edwards IR, et al. Rhabdomyolysis reported for children and adolescents treated with antipsychotic medicines: a case series analysis. J Child Adolesc Psychopharmacol. 2012; 22: 440-51. [CrossRef]
  • Rosebush PI, Stewart T, Mazurek MF. The treatment of neuroleptic malignnant syndrome. Are dantrolene and bromocriptine useful adjuncts to supportive care? Br J Psychiatry 1991; 159: 709-12. [CrossRef]
  • Sarısoy G, Kaçar ÖF, Pazvantoğlu O. Duloksetin-Siprofloksasin Birlikte Kullanımıyla İlişkili Serotonin Sendromu: Olgu Bildirimi. Klinik Psikofarmakoloji Bülteni 2012; 22: 79-82.
  • Şengül CB, Yalın Ş, Değirmencioğlu B, Şengül C. Risperion Kullanımına Bağlı Katatoni Gelişen Bir Ergen; Nöroleptik Malign Sendromla Ayırıcı Tanısı. Turk J Child Adolesc Ment Health. 2010; 17: 175-9.
  • Lee JW. Neuroleptic-induced catatonia: clinical presentation, response to benzodiazepines, and relationship to neuroleptic malignant syndrome. J Clin Psychopharmacol 2010; 30: 3-10. [CrossRef]

A Neuroleptic Malignant Syndrome Case Presented to the Pediatric Emergency Service

Yıl 2015, Cilt: 6 Sayı: 1, 19 - 22, 01.01.2015

Öz

Introduction: Neuroleptic malignant syndrome (NMS) is a rare but life-threatening condition induced by antipsychotic drug usage. The history of a patient presented with high fever, muscle rigidity, and loss of consciousness to the emergency service should be carefully analyzed.Case Report: A 14-year-old boy with mutism, dysphagia, loss of consciousness, and urine incontinence was presented to our emergency service. Analysis of the patient’s history revealed that he was administered risperidone (100 mg) for10 days. The boy looked sick and confused on examination. The laboratory findings were nearly normal. The patient was diagnosed with NMS and was transfered to the pediatric intensive care unit.Conclusion: NMS is a fatal clinical contidition and should be diagosed immediately. The patient’s history should be carefully analyzed. NMS should be immediately diagnosed if there is a history of antipsycotic drug usage

Kaynakça

  • Neuhut R, Lindenmayer JP, Silva R. Neuroleptic Malignant Syndrome in Children and Adolescents on Atypical Antipsychotic Medication: A Review. J Child Adolesc Psychopharmacol. 2009; 19 : 415-22. [CrossRef]
  • Rasimas JJ, Liebelt EL. Adverse Effects and Toxicity of the Atypical Antipsychotics: What is Important for the Pediatric Emergency Medicine Practitioner Clin Pediatr Emerg Med. 2012; 13: 300-10.
  • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Text Revision. Washington, DC, American Psychiatric Association, 2000.
  • Nierenberg D, Disch M, Manheimer E, Patterson J, Ross J, Sivestri G, et al. Facilitating prompt diagnosis and treatment of the neuroleptic malignant syndrome. Clin Pharmacol Ther 1991; 50: 580-6. [CrossRef]
  • Doğan N, Kürşad H, Erdem AF, Kızılkaya M. Nöroleptik Malin Sendromda Nadir Etyolojik Faktörler ve Klinik Seyir. AÜTD 2003; 35: 23-6.
  • Rasmussen KG. Risk factors for neuroleptic malignant syndrome. Am J Psychiatry 1998; 155: 1639-40. [CrossRef]
  • Steele D, Keltner NL, McGuiness TM. Are neuroleptic malignant syndrome and serotonin syndrome the same syndrome? Perspect Psychiatr Care 2011; 47: 58-62. [CrossRef]
  • Çakın Memik N, karakay I, Çoşkun A, Ağaoğlu B. Erken Ergenlikte Nöroleptik Malign Sendrom: Bir Olgu Sunumu. Çocuk ve Gençlik Ruh Sağlığı Dergisi 2006; 13: 124-9.
  • Star K, Lessa N, Almandil NB, Wilton L, Curran S, Edwards IR, et al. Rhabdomyolysis reported for children and adolescents treated with antipsychotic medicines: a case series analysis. J Child Adolesc Psychopharmacol. 2012; 22: 440-51. [CrossRef]
  • Rosebush PI, Stewart T, Mazurek MF. The treatment of neuroleptic malignnant syndrome. Are dantrolene and bromocriptine useful adjuncts to supportive care? Br J Psychiatry 1991; 159: 709-12. [CrossRef]
  • Sarısoy G, Kaçar ÖF, Pazvantoğlu O. Duloksetin-Siprofloksasin Birlikte Kullanımıyla İlişkili Serotonin Sendromu: Olgu Bildirimi. Klinik Psikofarmakoloji Bülteni 2012; 22: 79-82.
  • Şengül CB, Yalın Ş, Değirmencioğlu B, Şengül C. Risperion Kullanımına Bağlı Katatoni Gelişen Bir Ergen; Nöroleptik Malign Sendromla Ayırıcı Tanısı. Turk J Child Adolesc Ment Health. 2010; 17: 175-9.
  • Lee JW. Neuroleptic-induced catatonia: clinical presentation, response to benzodiazepines, and relationship to neuroleptic malignant syndrome. J Clin Psychopharmacol 2010; 30: 3-10. [CrossRef]
Toplam 13 adet kaynakça vardır.

Ayrıntılar

Diğer ID JA56GB93KZ
Bölüm Case Report
Yazarlar

Onur Balcı Bu kişi benim

Mehmet Arda Kılınç Bu kişi benim

İlknur Ucuz Bu kişi benim

Ali Yıldırım Bu kişi benim

Mehmet Yusuf Sarı Bu kişi benim

Yayımlanma Tarihi 1 Ocak 2015
Gönderilme Tarihi 1 Ocak 2015
Yayımlandığı Sayı Yıl 2015 Cilt: 6 Sayı: 1

Kaynak Göster

APA Balcı, O., Kılınç, M. A., Ucuz, İ., Yıldırım, A., vd. (2015). A Neuroleptic Malignant Syndrome Case Presented to the Pediatric Emergency Service. Journal of Emergency Medicine Case Reports, 6(1), 19-22.
AMA Balcı O, Kılınç MA, Ucuz İ, Yıldırım A, Sarı MY. A Neuroleptic Malignant Syndrome Case Presented to the Pediatric Emergency Service. Journal of Emergency Medicine Case Reports. Ocak 2015;6(1):19-22.
Chicago Balcı, Onur, Mehmet Arda Kılınç, İlknur Ucuz, Ali Yıldırım, ve Mehmet Yusuf Sarı. “A Neuroleptic Malignant Syndrome Case Presented to the Pediatric Emergency Service”. Journal of Emergency Medicine Case Reports 6, sy. 1 (Ocak 2015): 19-22.
EndNote Balcı O, Kılınç MA, Ucuz İ, Yıldırım A, Sarı MY (01 Ocak 2015) A Neuroleptic Malignant Syndrome Case Presented to the Pediatric Emergency Service. Journal of Emergency Medicine Case Reports 6 1 19–22.
IEEE O. Balcı, M. A. Kılınç, İ. Ucuz, A. Yıldırım, ve M. Y. Sarı, “A Neuroleptic Malignant Syndrome Case Presented to the Pediatric Emergency Service”, Journal of Emergency Medicine Case Reports, c. 6, sy. 1, ss. 19–22, 2015.
ISNAD Balcı, Onur vd. “A Neuroleptic Malignant Syndrome Case Presented to the Pediatric Emergency Service”. Journal of Emergency Medicine Case Reports 6/1 (Ocak 2015), 19-22.
JAMA Balcı O, Kılınç MA, Ucuz İ, Yıldırım A, Sarı MY. A Neuroleptic Malignant Syndrome Case Presented to the Pediatric Emergency Service. Journal of Emergency Medicine Case Reports. 2015;6:19–22.
MLA Balcı, Onur vd. “A Neuroleptic Malignant Syndrome Case Presented to the Pediatric Emergency Service”. Journal of Emergency Medicine Case Reports, c. 6, sy. 1, 2015, ss. 19-22.
Vancouver Balcı O, Kılınç MA, Ucuz İ, Yıldırım A, Sarı MY. A Neuroleptic Malignant Syndrome Case Presented to the Pediatric Emergency Service. Journal of Emergency Medicine Case Reports. 2015;6(1):19-22.