ST Yükselmesiz Akut Koroner Sendrom Hastalarında TIMI Risk Skoru ile Hemoglobin Değeri Arasındaki İlişkinin Değerlendirilmesi

Yıl 2016, Cilt: 19 Sayı: 1, 32 - 36, 04.04.2016

Çetin Geçmen Ekrem Güler Gamze Babur Güler Ali Elveran Hacı Murat Güneş Hicaz Zencirkıran Aguş Oğuz Karaca Nurşen Keleş Özlem Esen Ali Metin Esen

Öz

Giriş: ST yükselmesiz
akut koroner sendrom hastalarının geliş hemoglobin seviyesi ile TIMI risk skoru
arasındaki ilişki araştırıldı.

Hastalar ve Yöntem: ST yükselmesiz
akut koroner sendromlu 286 hasta çalışmaya dahil edildi. Tüm hastaların geliş
anında hemoglobin ve biyokimyasal parametreleri çalışıldı. Hastalar TIMI risk
skoruna göre düşük, orta ve yüksek risk olarak 3 gruba ayrıldı.

Bulgular: Geliş
hemoglobin seviyesi (g/dL) düşük, orta ve yüksek TIMI risk grubunda sırasıyla
(13.5 ± 1.9, 12.5 ± 1.9, 11.3 ± 1.9, p< 0.001) olarak saptandı. Hemoglobin
seviyesi ve TIMI risk skoru arasında orta düzeyde negatif korelasyon bulundu
(r: -0.408, p< 0.001). Tek değişkenli regresyon analizinde TIMI risk skoru
artışı ile geliş hemoglobin seviyelerinin önemli derecede düşük olduğu saptandı
(Estimate; -0.406, p< 0.001, %95 GA[-0.521-(-0.290)].

Sonuç: ST yükselmesiz
akut koroner sendrom ile hastaneye yatırılan hastaların risk skoru attıkça
geliş hemoglobin seviyelerinin bağlantılı olarak düşük olduğu tespit edildi.
Basit ve yaygın bir test olarak kullanılan hemoglobin seviyesi, ST yükselmesiz
akut koroner sendrom hastalarının geliş anındaki risk durumunu belirlemede
kullanılabilir.

Anahtar Kelimeler

Miyokart infarktüsü, hemoglobinler, akut koroner sendrom

Evaluation of the Relationship Between Hemoglobin Levels and Thrombolysis in Myocardial Infarction Risk Score in Patients with Non-ST Elevation Acute Coronary Syndrome

Öz

Introduction: The relationship between
hemoglobin (Hb) levels at admission and the thrombolysis in myocardial
infarction (TIMI) risk score in patients with non-ST elevation acute coronary
syndrome (NSTE-ACS) was investigated.

Patients and Methods: In total, 286 NSTE-ACS
patients were included in the study. Hb levels and biochemical parameters were
measured at admission. The patients were grouped into the following three
groups according to the TIMI risk score: low-intermediate-, and high-risk
groups.

Results: Hb levels (in g/dL) at
admission in low-, intermediate-, and high-risk groups were 13.5 ± 1.9, 12.5 ±
1.9, and 11.3 ± 1.9, respectively (p < 0.001). We found a negative moderate
correlation between Hb levels and TIMI risk scores (r= -0.408, p < 0.001).
In univariate regression analysis, it was found that with the increase in the
TIMI risk score, Hb levels at admission were significantly reduced (estimate= -0.406;
p< 0.001; 95% confidence interval; -0.521 to -0.290).

Conclusion:
We found that as the TIMI risk score of patients admitted to
hospital presenting with NSTE-ACS increased, their Hb levels at admission
correspondingly decreased. Thus, the simple and commonly measured Hb level can
be a useful parameter in stratifying the risks of patients presenting with
NSTE-ACS during admission.

Anahtar Kelimeler

Myocardial infarction, hemoglobins, acute coronary syndrome

Kaynakça

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