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Besinler ve Beslenme Çalışmalarında Drosophila

Yıl 2016, Cilt: 19 Sayı: 3, 236 - 243, 29.10.2016

Öz

Bu çalışma, beslenme yoluyla vücuda alınan birçok besinin model organizma olarak kullanılan Drosophila melanogaster üzerinde meydana getirdiği değişikliklerin açıklanması amacıyla hazırlanmış bir derlemedir. Birçok bitkinin doğal kullanımları dışında, alternatif  tıpta ilaç ve antioksidan madde olarak da kullanıldığı bilinmektedir. Kullanım miktarına bağlı olarak antimikrobiyal etki, biyolojik parametreler üzerinde değişme ve oksidan-antioksidan özelliklere sahiptirler. Çeşitli kimyasallar, gıda katkıları, baharatlar, bitkiler ve yağları D. melanogaster üzerinde morfolojik, fizyolojik, biyokimyasal tepkilere neden olmaktadır. Yapay besine eklenen bitkisel ürünlerin güvenli tüketim miktarlarının model organizmalarda denenerek belirlenmesi, insan gibi besin zinciri yoluyla etkilenebilecek canlılar için önem arz etmekte ve daha ayrıntılı çalışmaların yapılma gereğini ortaya çıkarmaktadır.

Anahtar Kelimeler: Beslenme, Drosophila, Bitkisel ürünler.

 

Drosophila In Food And Nutrition Studies

 

ABSTRACT: This is a review study aimed to describe the changes on a model organism, Drosophila melanogaster by taking varies nutrition into the body. Many plants, with the exception of being used naturally,  are known to be used in alternative medicine as a drug or antioxidant sustance. Depending on the amount of usage; these substances could have an effect of antimicrobial activity, changes on the biological parameters and oxidant- antioxidant effects. It is observed that various chemicals, food additives, spices or flavorings herbs and oils used in traditional or local dishes cause morphological, physiological, biochemical responses on D. melanogaster. Determination of safe consumption amount of herbal products added to artificial food is important to human beings affected through the food chain and presents more detailed and required study.

Key words: Nutrition, Drosophila, Herbal products.

Kaynakça

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Yıl 2016, Cilt: 19 Sayı: 3, 236 - 243, 29.10.2016

Öz

Kaynakça

  • Adams, M.D., Celniker, S.E., Holt, R.A., Evans, C.A., Gocayne, J.D., Amanatides, PG. 2000. The Genome Sequence of Drosophila melanogaster. Science, 287(5461): 2185-2195.
  • Adler, M.I., Bonduriansky, R. 2014. Why Do The Well-Fed Appear To Die Young?: A New Evolutionary Hypothesis For The Effect Of Dietary Restriction On Lifespan. Bioessays, 36: 439-450.
  • Altun Çolak, D. 2013. Dioksinlerin Toksik Etkilerinin Drosophila Kanat Benek Testi Ve Biyokimyasal Yöntemlerle Belirlenmesi ve Bu Etkilerin Farklı Antioksidanlar İle Giderilmesi Üzerine Araştırmalar. AÜ.Fen Bil. Ens., Biyoloji ABD, Doktora Tezi, 171 s.
  • Andersen, L.H., Kristensen, T.N., Loeschcke, V., Toft, S., Mayntz, D. 2010. Protein And Carbohydrate Composition Of Larval Food Affects Tolerance To Thermal Stress And Desiccation in Adult Drosophila melanogaster. Journal of Insect Physiology, 56: 336-340.
  • Azırak, S. 2007. Thymol ve Carvacrol’un in Vivo Genotoksik Etkilerinin Araştırılması. ÇÜ.Fen Bil. Ens., Biyoloji ABD, Doktora Tezi, 142 s.
  • Bahadorani, S., Hilliker, A.J. 2008. Cocoa Confers Life Span Extension in Drosophila melanogaster. Nutrition Research, 28: 377-382.
  • Bass, T.M., Grandison, R.C., Wong,R., Martinez, P., Partridge, L., Piper, M.D.W. 2007. Optimization of Dietary Restriction Protocols in Drosophila. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 1071-108.
  • Benli, D. 2013. Bazı gıda koruyucularının Drosophila melanogaster’in Yaşama Yüzdesi Ve Ömür Uzunluğu Üzerine Etkisinin Araştırılması. CÜ. Fen Bil. Ens.,Yüksek Lisans Tezi, Biyoloji ABD, 101s.
  • Botsoglou, E., Govaris, A., Christaki, E., Botsoglou, N. 2010. Effect of Dietary Olive Leaves and/or α-tocopheroyl Acetate Supplementation on Microbial Growth and Lipid Oxidation of Turkey Breast Fillets During Refrigerated Storage. Food Chemistry, 121:17-22.
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  • Burger, J.S.M., Hwangbo, D.S., Corby-Harris, V., Promislow, D.E.L. 2007. The Functional Costs And Benefits Of Dietary Restriction in Drosophila. Aging Cell, 6: 63-71.
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  • Jafari, M.,Felgner, J.S., Bussel, I.I., Hutchili, T.,Khodayari, B.,Rose, M.R., Vince-Cruz, C.,Mueller, L.D. 2007. Rhodiola: A Promising Anti-Aging Chinese Herb. Rejuvenatıon Research, 10(4): 587-602.
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  • Krishna, M.S., Watson, V. 2013. The Effect Of Pyrogallol On The Pre-Adult Futures of Drosophila bipectinata. Drosophila Information Service, 96:157-164.
  • Lashmanova, E., Proshkinab, E., Zhikrivetskayaa, S., Shevchenko, O., Marusich, E., Leonov, S., Melerzanov, A., Zhavoronkov, A., Moskalev, A. 2015. Fucoxanthin İncreases Lifespan of Drosophila melanogaster and Caenorhabditis elegans. Pharmacological Research, 100: 228-241.
  • Lazutka, J.R., Mierauskien, J., Slapsyte, G., Dedonyte, V. 2001. Genotoxicity Of Dill (Anethum graveolens L.), Peppermint (Mentha piperita L.) and Pine (Pinus sylvestris L.) Essential Oils İn Human Lymphocytes and Drosophila melanogaster. Food and Chemical Toxicology, 39(5): 485-492.
  • Lee, K.P., Simpson, S.J., Wilson, K. 2008a. Dietary Protein-Quality İnfluences Melanization And Immune Function in An Insect. Functional Ecology, 22: 1052-1061.
  • Lee, K.P., Simpson, S.J., Clissold, F.J., Brooks, R., Ballard, J.W.O. 2008b. Lifespan and Reproduction in Drosophila: New Insights From Nutritional Geometry. Proceedings of the National Academy of Sciences, 105: 2498-2503.
  • Li, Y.M., Chan, H.Y.E., Yao, X.Q., Huang, Y., Chen, Z.Y. 2008. Green Tea Catechins And Broccoli Reduve Fat-İnduced Mortality in Drosophila melanogaster. Journal of Nutritional Biochemistry, 19: 376-383.
  • Mair, W., Piper, M.D.W., Partridge, L. 2005. Calories Do Not Explain Extension of Life Span by Dietary Restriction in Drosophila. PLoS biology, 3(7): 1305-1311.
  • Mihajilov-Krstev, T., Jovanović, B., Jović, J., Ilić, B., Miladinović, D., Matejić, J., Rajković, J., Đorđević, L., Cvetković, V., Zlatković, B. 2014. Antimicrobial, Antioxidative, and Insect Repellent Effects of Artemisia absinthium Essential Oil. Planta Med, 80: 1698-1705.
  • Min, K.J., Flatt, T., Kulaots, I., Tatar, M., 2007. Counting Calories in Drosophila Diet Restriction. Experimental Gerontology, 42: 247-251.
  • Partridge, L., Hoffman, A., Jones, S. 1987. Male Size And Mating Success in Drosophila melanogaster and Drosophila pseudoobscura Under Field Conditions. Animal Behaviour, 35: 468-476.
  • Pavlidou, V., Karpouhtesis, I., Franzios, G., Zambetaki, A., Scouras, Z., Mavragani-Tsipidou, P. 2004. Insecticidal and Genotoxic Effects Of Essential Oils Of Greek sage, Salvia fruticosa, and Mint, Mentha pulegium, on Drosophila melanogaster and Bactrocera oleae (Diptera: Tephritidae). Journal of Agricultural and Urban Entomology, 21(1): 39-49.
  • Peng, C., Zuo, Y.Y., Kin, M.K., Liang, Y.T., Ma, K.Y., Chan, H.Y.E., Huang, Y.,Yu, H.J., Chen, Z.Y., 2012. Blueberry Extract Prolongs Lifespan of Drosophila melanogaster. Experimental Gerontology, 47: 170-178.
  • Peric-Mataruga, V., Blagojevic, D., Spasic, M.B., Ivanovic, J., Jankovic-Hladni, M. 1997. Effect of The Host Plant On The Antioxidative Defence İn The Midgut of Lymantria dispar L. Caterpillars Of Different Population Origins. Journal of Insect Physiology, 43: 101-106.
  • Piper, M.D.W , Mair, W., Partridge, L. 2005a. Counting the Calories: The Role of Specific Nutrients in Extension of Life Span by Food Restriction. Journal of Gerontolog, 60A(5): 549-555.
  • Piper, M.D.W., Skorupa, D., Partridge, L. 2005b. Diet, Metabolism And Lifespan in Drosophila. Journal of Experimental Gerontolog, 40: 857-862.
  • Podder, S., Roy, S. 2014. Exposure-dependent Variation İn Cryolite İnduced Lethality in The Nontarget Insect, Drosophila melanogaster. Interdisciplinary Toxicology, 7(1): 17-22.
  • Reed, L.K., Williams, S., Springston, M., Brown, J., Freeman, K., DesRoches, C.E., Sokolowski, M.B., Gibson, G. 2010. Genotype-by-Diet Interactions Drive Metabolic Phenotype Variation in Drosophila melanogaster. Genetics, 185: 1009-1019.
  • Rharrabe, K., Amri, H., Bouayad, N., Sayah, F. 2008. Effects of Azadirachtin On Post-Embryonic Development, Energy Reserves And Α-Amylase Activity of Plodia interpunctella Hübner (Lepidoptera: Pyralidae). Journal of Stored Products Research, 44: 290-294.
  • Ridley, E.V. 2011. The impact of chlortetracycline on Drosophila melanogaster and Aedes aegypti. Universty of York, Department of Biology, Ph. D. Tesis, 281p.
  • Rion, S., Kawecki, T.J. 2007. Evolutionary Biology Of Starvation Resistance: What We Have Learned From Drosophila. Journal of Evolutionary Biology, 20: 1655-1664.
  • Sang, J.H. 1956. The Quantitative Nutritional Requirements of Drosophila melanogaster. Journal of Experimental Biology, 45-72.
  • Sarıkaya, R., Çakır, Ş., Solak, K. 2006. Gıdalardaki Koruyucu Maddelerin Drosophila melanogaster’de (mwh x flr) Ömür Uzunluğuna Etkisi. Kastamonu Eğitim Dergisi, 14(1): 173-184.
  • Sato, H., Genet, C, Strehle, A. 2007. Anti-Hyperglycemic Activity of a TGR5 Agonist Isolated from Olea europaea. Biochemical and Biophysical Research Communications, 362(4): 793-798.
  • Sentinella, A.T., Crean, A.J , Bonduriansky, R. 2013. Dietary Protein Mediates A Trade-Off Between Larval Survival And The Development Of Male Secondary Sexual Traits. Functional Ecology, 27: 1134-144.
  • Sisodia, S., Singh, B.N. 2012. Experimental Evidence for Nutrition Regulated Stress Resistance in Drosophila ananassae. Plos One, 7(10): 1-9.
  • Smith, E.M., Hoi, J.T., Eissenberg, J.C., Shoemaker, J.D., Neckameyer, W.S. 2007. Feeding Drosophila A Biotin-Deficient Diet For Multiple Generations Increases Stress Resistance And Lifespan And Alters Gene Expression And Histone Biotinylation Patterns. Journal of Nutrition, 137: 2006-2012.
  • Sofija, P.L.,Trajković, J., Savić, T. 2013. Mating Frequency of Drosophila melanogaster Strains Reared On Carrot And Banana Diets. Drosophila Information Service, 96: 4-6.
  • Sohal, R.S., Weindruch, R. 1996. Oxidative Stress, Caloric Restriction, And Aging. Science, 273: 59-63.
  • Sun, X., Seeberger, J., Alberico, T., Wang, C., Wheeler, C.T., Schauss, A.G., Zou, S. 2010. Açai Palm Fruit (Euterpe oleracea Mart.) Pulp Improves Survival Of Flies On A High Fat Diet. Experimental Gerontology, 45: 243-251.
  • Tettweiler, G., Miron, M., Jenkins, M., Sonenberg, N., Lasko1, P.F. 2005. Starvation and Oxidative Stress Resistance in Drosophila Are Mediated Through The Eıf4e-Binding Protein, d4E-BP. Genes and Development, 19: 1840-1843.
  • Turna, F. 2012. Resveratrol’ün Drosophila melanogaster’de Antigenotoksik Etkilerinin Araştırılması. AÜ. Fen Bil. Ens., Biyoloji ABD, Yüksek Lisans Tezi, 81 s.
  • Unckless, R.L., Rottschaefer, S.M., Lazzaro, B.P. 2015. The Complex Contributions of Genetics and Nutrition to immunity in Drosophila melanogaster. PLOS Genetics, 1-26.
  • Uysal, H., Altun, D., Aslan, A. 2009. Drosophila melanogaster’de Lobaria pulmonaria (L.) Hoffm. Likeninin Ömür Uzunluğu Üzerine Etkisi. Tübav Bilim Dergisi, 2(3): 271-276.
  • Uzunlar, N., Yavuzyiğit, B.B., İzgü, D. 2014. Ahlatın Gücü: ahlat (Pyrus elaeagrifolia) Meyve Ekstresinin Antigenotoksik Etkilerinin Drosophila melanogaster Üzerinde Kanat Smart Analizi İle Araştırılması. tedprints.tedankara.k12.tr/445/1/Nilsu_Bilge.pdf. (Erişim tarihi: 1.06.2015).
  • Ünver, S., Uysal, H. 2014. Neonikotinoid İnsektisitlere Bağlı Olarak Drosophila melanogaster’in AChE Aktivitesinde Meydana Gelen Değişikliklerin Bitkisel Ekstraktlar ile Giderilmesi Üzerine Araştırmalar. Cumhuriyet Üniversitesi Fen Fakültesi Fen Bilimleri Dergisi, 35(4): 107-116.
  • Wang, L., Clark, A.G. 1995. Physiological Genetics Of The Response To A High Sucrose Diet By Drosophila melanogaster. Biochemical Genetics, 33: 149-165.
  • Wang, M.H., Lazebny,O., Harshman, L.G., Nuzhdin, S.V. 2004. Environment Dependent Survival of Drosophila melanogaster: A Quantitative Genetic Analysis. Aging, 133-140.
  • Wenzel, U. 2006. Nutrition, Sirtuins And Aging. Genetics and Nutrition, 1: 85-93.
  • Wheeler, M.R. 1981. The Drosophilidae: A Taxonomic Overview. (The Genetics and Biology of Drosophila; J. N. Academic Press INC. Ltd.,London, Ed. Ashburner,M., Carsen, H.L., Thompson, J.) 3a: 1-84.
  • Wong, A.C.N., Dobson, A.J., Douglas, A.E. 2014. Gut Microbiota Dictates The Metabolic Response Of Drosophila to Diet. Journal of Experimental Biology, 217: 1894-1901.
  • Woodruff, R.C., Mason, J.M., Valencia, R., Zimmering, S. 1985. Chemical Mutagenesis Testing in Drosophila. V. Results of 53 Coded Compounds Tested For the National Toxicology Program. Environmental Mutagenesis, 7: 677-702.
  • Yıldız, M., 2013. Timol ve Karvakrolün Drosophila melanogaster Asetilkolinesteraz Enzimi Üzerine Etkilerinin Araştırılması. AÜ. Fen Bil. Ens., Moleküler Biyoloji ve Genetik ABD, Yüksek Lisans Tezi, 68 s.
  • Zhang, Z., Han, S., Wang, H., Wang, T. 2014. Lutein Extends The Lifespan Of Drosophila melanogaster. Archives of Gerontology and Geriatrics, 58: 153-159.
Toplam 92 adet kaynakça vardır.

Ayrıntılar

Bölüm Makaleler
Yazarlar

Eda Güneş

Yayımlanma Tarihi 29 Ekim 2016
Yayımlandığı Sayı Yıl 2016 Cilt: 19 Sayı: 3

Kaynak Göster

APA Güneş, E. (2016). Besinler ve Beslenme Çalışmalarında Drosophila. KSÜ Doğa Bilimleri Dergisi, 19(3), 236-243.
AMA Güneş E. Besinler ve Beslenme Çalışmalarında Drosophila. KSÜ Doğa Bilimleri Dergisi. Ekim 2016;19(3):236-243.
Chicago Güneş, Eda. “Besinler Ve Beslenme Çalışmalarında Drosophila”. KSÜ Doğa Bilimleri Dergisi 19, sy. 3 (Ekim 2016): 236-43.
EndNote Güneş E (01 Ekim 2016) Besinler ve Beslenme Çalışmalarında Drosophila. KSÜ Doğa Bilimleri Dergisi 19 3 236–243.
IEEE E. Güneş, “Besinler ve Beslenme Çalışmalarında Drosophila”, KSÜ Doğa Bilimleri Dergisi, c. 19, sy. 3, ss. 236–243, 2016.
ISNAD Güneş, Eda. “Besinler Ve Beslenme Çalışmalarında Drosophila”. KSÜ Doğa Bilimleri Dergisi 19/3 (Ekim 2016), 236-243.
JAMA Güneş E. Besinler ve Beslenme Çalışmalarında Drosophila. KSÜ Doğa Bilimleri Dergisi. 2016;19:236–243.
MLA Güneş, Eda. “Besinler Ve Beslenme Çalışmalarında Drosophila”. KSÜ Doğa Bilimleri Dergisi, c. 19, sy. 3, 2016, ss. 236-43.
Vancouver Güneş E. Besinler ve Beslenme Çalışmalarında Drosophila. KSÜ Doğa Bilimleri Dergisi. 2016;19(3):236-43.