Öz
Therapeutic drug monitoring specializes in the measurement of drug concentrations in biological fluids and may serve as a practical aid to clarify various conditions of unexpect response to chronic drug treatment. Briefly, its main purpose is to optimize and/or individualize dosage regimens to maintain efficient and safe drug therapy. This is acieved by maintaining serum/plasma drug concentrations within a target range (therapeutic range, therapeutic window), which is defined as the range of plasma drug concentrations that produce therapeutic effects with minimal risk of adverse responses/side or toxic effects. In this review, indications, practical applications as well as the clinical value and cost-effectiveness of therapeutic drug monitoring is discussed
Öz
Therapeutic drug monitoring specializes in the measurement of drug concentrations in biological fluids and may serve as a practical aid to clarify various conditions of unexpect response to chronic drug treatment. Briefly, its main purpose is to optimize and/or individualize dosage regimens to maintain efficient and safe drug therapy. This is acieved by maintaining serum/plasma drug concentrations within a target range (therapeutic range, therapeutic window), which is defined as the range of plasma drug concentrations that produce therapeutic effects with minimal risk of adverse responses/side or toxic effects. In this review, indications, practical applications as well as the clinical value and cost-effectiveness of therapeutic drug monitoring is discussed.
Anahtar Kelimeler
Terapötik ilaç izlemi terapötik aralık terapötik pencere klinik farmakoloji klinik eczacılık
Ayrıntılar
| Diğer ID | JA73RT22NJ |
|---|---|
| Bölüm | Araştırma Makalesi |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Mayıs 2017 |
| Yayımlandığı Sayı | Yıl 2017 Cilt: 1 Sayı: 1 |