BibTex RIS Kaynak Göster

Vesicular stomatitis virus (VSV) as a paradigm for predicting antiviral activity against Ebola virus (EBOV)

Yıl 2015, Cilt: 19 Sayı: 2, 141 - 152, 06.04.2015

Öz

There are at present no antivirals available which have been
formally licensed for clinical use for the treatment of Ebola
virus (EBOV) infections in humans. The most advanced to be
approved for this purpose is favipiravir (T-705), a viral RNA
polymerase inhibitor. Under consideration are BCX4430, also
a viral RNA polymerase inhibitor, and 3-deazaneplanocin A
and various other S-adenosylhomocysteine (SAH) hydrolase
inhibitors. A number of compounds which have been approved
for other purposes seem to interact with the cell entry of
EBOV. Some compounds like pyrazofurin have been found to
be exquisitely potent inhibitors of vesicular stomatitis virus
(VSV). VSV belongs to the rhabdoviridae, a family closely
related to the family of the filoviridae to which EBOV and
Marburg virus belong. VSV, unlike EBOV and Marburg virus
which require biosafety level 4, can be handled in conventional
safety conditions.
Key words: Ebola virus (EBOV); vesicular stomatitis virus
(VSV); rhabdoviridae; filoviridae; favipiravir; BCX4430;
pyrazofurin; SAH hydrolase

Kaynakça

  • Isaacs A, Lindenmann J. Virus interference. I. Interferon. Proc Royal Soc London 1957;147: 258-67.
  • Pattyn S, Jacob W, van der Groen G, Piot P, Courteille G. Isolation of Marburg-like virus from a case of haemorrhagic fever in Zaire. Lancet 1977;309: 573-4.
  • De Clercq E, De Somer P. Protective effect of interferon and polyacrylic acid in newborn mice infected with a lethal dose of vesicular stomatitis virus. Life Sci 1968;7: 925-33.
  • Haagmans BL, Kuiken T, Martina BE, Fouchier RA, Rimmelzwaan GF, van Amerongen G, van Riel D, de Jong T, Itamura S, Chan KH, Tashiro M, Osterhaus AD. Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques. Nat Med 2004;10: 290-3.
  • Smith LM, Hensley LE, Geisbert TW, Johnson J, Stossel A, Honko A, Yen JY, Geisbert J, Paragas J, Fritz E, Olinger G, Young HA, Rubins KH, Karp CL. Interferon-β therapy prolongs survival in rhesus macaque models of Ebola and Marburg hemorrhagic fever. J Infect Dis 2013;208: 310-8.
  • Baba M, Snoeck R, Pauwels R, De Clercq E. Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus. Antimicrob Agents Chemother 1988;32: 1742-5.
  • Ito M, Baba M, Hirabayashi K, Matsumoto T, Suzuki M, Suzuki S, Shigeta S, De Clercq E. In vitro activity of mannan sulfate, a novel sulfated polysaccharide, against human immunodeficiency virus type 1 and other enveloped viruses. Eur J Clin Microbiol 1989;8: 171-3.
  • Baba M, Nakajima M, Schols D, Pauwels R, Balzarini J, De Clercq E. Pentosan polysulfate, a sulfated oligosaccharide, is a potent and selective anti-HIV agent in vitro. Antiviral Res 1988;9: 335-43.
  • Ueno R, Kuno S. Dextran sulphate, a potent anti-HIV agent in vitro having synergism with zidovudine. Lancet 1987;i: 1379.
  • Ito M, Baba M, Sato A, Pauwels R, De Clercq E, Shigeta S. Inhibitory effect of dextran sulfate and heparin on the replication of human immunodeficiency virus (HIV) in vitro. Antiviral Res 1987;7: 361-7.
  • Baba M, Pauwels R, Balzarini J, Arnout J, Desmyter J, De Clercq E. Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro. Proc Natl Acad Sci USA 1988;85: 6132-6.
  • Mitsuya H, Looney DJ, Kuno S, Ueno R, Wong-Staal F, Broder S. Dextran sulfate suppression of viruses in the HIV family: inhibition of virion binding to CD4+ cells. Science 1988;240: 646-9.
  • Witvrouw M, Desmyter J, De Clercq E. Antiviral portrait series: 4. Polysulfates as inhibitors of HIV and other enveloped viruses. Antivir Chem Chemother 1994;5: 345-59.
  • Witvrouw M, Este JA, Mateu MQ, Reymen D, Andrei G, Snoeck R, Ikeda S, Pauwels R, Bianchini NV, Desmyter J, De Clercq E. Activity of a sulfated polysaccharide extracted from the red seaweed Aghardhiella tenera against human immunodeficiency virus and other enveloped viruses. Antivir Chem Chemother 1994;5: 297-303.
  • Witvrouw M, De Clercq E. Sulfated polysaccharides extracted from sea algae as potential antiviral drugs. Gen Pharmacol 1997;29: 497-511.

ORIGINAL RESEARCH

Yıl 2015, Cilt: 19 Sayı: 2, 141 - 152, 06.04.2015

Öz

-

Kaynakça

  • Isaacs A, Lindenmann J. Virus interference. I. Interferon. Proc Royal Soc London 1957;147: 258-67.
  • Pattyn S, Jacob W, van der Groen G, Piot P, Courteille G. Isolation of Marburg-like virus from a case of haemorrhagic fever in Zaire. Lancet 1977;309: 573-4.
  • De Clercq E, De Somer P. Protective effect of interferon and polyacrylic acid in newborn mice infected with a lethal dose of vesicular stomatitis virus. Life Sci 1968;7: 925-33.
  • Haagmans BL, Kuiken T, Martina BE, Fouchier RA, Rimmelzwaan GF, van Amerongen G, van Riel D, de Jong T, Itamura S, Chan KH, Tashiro M, Osterhaus AD. Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques. Nat Med 2004;10: 290-3.
  • Smith LM, Hensley LE, Geisbert TW, Johnson J, Stossel A, Honko A, Yen JY, Geisbert J, Paragas J, Fritz E, Olinger G, Young HA, Rubins KH, Karp CL. Interferon-β therapy prolongs survival in rhesus macaque models of Ebola and Marburg hemorrhagic fever. J Infect Dis 2013;208: 310-8.
  • Baba M, Snoeck R, Pauwels R, De Clercq E. Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus. Antimicrob Agents Chemother 1988;32: 1742-5.
  • Ito M, Baba M, Hirabayashi K, Matsumoto T, Suzuki M, Suzuki S, Shigeta S, De Clercq E. In vitro activity of mannan sulfate, a novel sulfated polysaccharide, against human immunodeficiency virus type 1 and other enveloped viruses. Eur J Clin Microbiol 1989;8: 171-3.
  • Baba M, Nakajima M, Schols D, Pauwels R, Balzarini J, De Clercq E. Pentosan polysulfate, a sulfated oligosaccharide, is a potent and selective anti-HIV agent in vitro. Antiviral Res 1988;9: 335-43.
  • Ueno R, Kuno S. Dextran sulphate, a potent anti-HIV agent in vitro having synergism with zidovudine. Lancet 1987;i: 1379.
  • Ito M, Baba M, Sato A, Pauwels R, De Clercq E, Shigeta S. Inhibitory effect of dextran sulfate and heparin on the replication of human immunodeficiency virus (HIV) in vitro. Antiviral Res 1987;7: 361-7.
  • Baba M, Pauwels R, Balzarini J, Arnout J, Desmyter J, De Clercq E. Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro. Proc Natl Acad Sci USA 1988;85: 6132-6.
  • Mitsuya H, Looney DJ, Kuno S, Ueno R, Wong-Staal F, Broder S. Dextran sulfate suppression of viruses in the HIV family: inhibition of virion binding to CD4+ cells. Science 1988;240: 646-9.
  • Witvrouw M, Desmyter J, De Clercq E. Antiviral portrait series: 4. Polysulfates as inhibitors of HIV and other enveloped viruses. Antivir Chem Chemother 1994;5: 345-59.
  • Witvrouw M, Este JA, Mateu MQ, Reymen D, Andrei G, Snoeck R, Ikeda S, Pauwels R, Bianchini NV, Desmyter J, De Clercq E. Activity of a sulfated polysaccharide extracted from the red seaweed Aghardhiella tenera against human immunodeficiency virus and other enveloped viruses. Antivir Chem Chemother 1994;5: 297-303.
  • Witvrouw M, De Clercq E. Sulfated polysaccharides extracted from sea algae as potential antiviral drugs. Gen Pharmacol 1997;29: 497-511.
Toplam 15 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Makaleler
Yazarlar

Erik De Clercq Bu kişi benim

Yayımlanma Tarihi 6 Nisan 2015
Yayımlandığı Sayı Yıl 2015 Cilt: 19 Sayı: 2

Kaynak Göster

APA De Clercq, E. (2015). Vesicular stomatitis virus (VSV) as a paradigm for predicting antiviral activity against Ebola virus (EBOV). Marmara Pharmaceutical Journal, 19(2), 141-152. https://doi.org/10.12991/mpj.20151910461
AMA De Clercq E. Vesicular stomatitis virus (VSV) as a paradigm for predicting antiviral activity against Ebola virus (EBOV). mpj. Nisan 2015;19(2):141-152. doi:10.12991/mpj.20151910461
Chicago De Clercq, Erik. “Vesicular Stomatitis Virus (VSV) As a Paradigm for Predicting Antiviral Activity Against Ebola Virus (EBOV)”. Marmara Pharmaceutical Journal 19, sy. 2 (Nisan 2015): 141-52. https://doi.org/10.12991/mpj.20151910461.
EndNote De Clercq E (01 Nisan 2015) Vesicular stomatitis virus (VSV) as a paradigm for predicting antiviral activity against Ebola virus (EBOV). Marmara Pharmaceutical Journal 19 2 141–152.
IEEE E. De Clercq, “Vesicular stomatitis virus (VSV) as a paradigm for predicting antiviral activity against Ebola virus (EBOV)”, mpj, c. 19, sy. 2, ss. 141–152, 2015, doi: 10.12991/mpj.20151910461.
ISNAD De Clercq, Erik. “Vesicular Stomatitis Virus (VSV) As a Paradigm for Predicting Antiviral Activity Against Ebola Virus (EBOV)”. Marmara Pharmaceutical Journal 19/2 (Nisan 2015), 141-152. https://doi.org/10.12991/mpj.20151910461.
JAMA De Clercq E. Vesicular stomatitis virus (VSV) as a paradigm for predicting antiviral activity against Ebola virus (EBOV). mpj. 2015;19:141–152.
MLA De Clercq, Erik. “Vesicular Stomatitis Virus (VSV) As a Paradigm for Predicting Antiviral Activity Against Ebola Virus (EBOV)”. Marmara Pharmaceutical Journal, c. 19, sy. 2, 2015, ss. 141-52, doi:10.12991/mpj.20151910461.
Vancouver De Clercq E. Vesicular stomatitis virus (VSV) as a paradigm for predicting antiviral activity against Ebola virus (EBOV). mpj. 2015;19(2):141-52.