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Primer Headaches And Over The Counter Use Of Painkillers In Pregnancy

Yıl 2014, Cilt: 5 Sayı: 18, 26 - 33, 03.03.2015
https://doi.org/10.17944/mkutfd.67514

Öz

Aim: The aim of this study is to demonstrate the characteristics of primary headaches during pregnancy, and the frequency of over the counter drug use by pregnant woman due to headache. Material and Methods: Third hundred and fifty women in the first three months of postpartum period were interviewed by a neurologist related to the headaches they have experienced during pregnancy, and their headache characteristics and their preferences in terms of prescription or over the counter drug use were examined. Results: Forty four of the 350 mothers were excluded from the study for various reasons. One hundred and twenty nine (42.2%) of the study participants expressed that they had not experienced any headaches. One hundred and seventy seven (57.8%) of them complained from primary headaches during their pregnancy. Forty four (24.8%) of headache sufferers sought medical advice from a medical doctor. While 83 (46.6%) of whom used drugs, only 36 (43.4%) of them consulted a physician to do so. Conclusion: The results of this study suggest that headaches experienced during pregnancy should be taken seriously, since it leads to uncontrolled drug use

Kaynakça

  • - Black RA, Hill DA. Over-the-counter medications in pregnancy. Am Fam Physician.
  • ; 15: 2517-24.
  • - Tillett J, Kostich LM, VandeVusse L. Use of over-the-counter medications during
  • pregnancy. J Perinat Neonatal Nurs. 2003;17: 3-18.
  • - Melhado E, Maciel JA Jr, Guerreiro CA. Headaches during pregnancy in women with a
  • prior history of menstrual headaches. Arq Neuropsiquiatr. 2005 ;63: 934-40.
  • - Granella F, Sances G, Pucci E, et al. Migraine with aura and reproductive life events: a
  • case control study. Cephalalgia. 2000;20: 701–7.
  • - Von Wald T, Walling AD. Headache during pregnancy. Obstet Gynecol Surv. 2002; 57:
  • -85.
  • - Maggioni F, Alessi C, Maggino T, Zanchin G. Headache during pregnancy. Cephalalgia.
  • ; 17: 765- 69.
  • - Peter J Goadsby, Jay Goldberg,Stephen D Silberstein. Migraine in pregnancy. BMJ; 2008:
  • -
  • - Pahim LS, Menezes AM, Lima R. Prevalence and factors associated to migraine in adult
  • population, Southern Brazil. Rev Saude Publica. 2006; 40: 692- 98.
  • - Sarchielli P, Tognoloni M, Russo S, et al. Variations in the platelet arginine/nitric oxide
  • pathway during the ovarian cycle in females affected by menstrual migraine. Cephalalgia.
  • ; 16: 468-75.
  • - Sachdeva P, Patel BG, Patel BK. Drug use in pregnancy; a point to ponder! Indian J
  • Pharm Sci. 2009; 71: 1-7.
  • - Uhl K, Kennedy DL, Kweder SL. Information on medication use in pregnancy. Am Fam
  • Physician. 2003; 15: 2476-78.
  • - Olesen C, Steffensen FH, Nielsen GL, de Jong-van den Berg L, Olsen J, Sørensen HT.
  • Drug use in first pregnancy and lactation: a population-based survey among Danish
  • women. The EUROMAP group. Eur J Clin Pharmacol. 1999; 55: 139-44.
  • - Olesen C, Thrane N, Henriksen TB, Ehrenstein V, Olsen J. Associations between socioeconomic
  • factors and the use of prescription medication during pregnancy: a populationbased
  • study among 19,874 Danish women. Eur J Clin Pharmacol. 2006; 62: 547-53.
  • - Göbel H, Petersen-Braun M, Soyka D. The epidemiology of headache in Germany: a
  • nationwide survey of a representative sample on the basis of the headache classification of
  • the International Headache Society. Cephalalgia. 1994; 142: 97-106.
  • - Launer LJ, Terwindt GM, Ferrari MD. The prevalence and characteristics of migraine in a
  • population-based cohort: the GEM study. Neurology. 1999; 53: 537- 42.
  • - Menon R, Bushnell CD. Headache and pregnancy. Neurologist. 2008; 14: 108-19.
  • - Pau K, Hess D, Kohama S, et al. Oestrogen upregulates noradrenaline release in the
  • mediobasal hypothalamus and tyrosine hydroxylase gene expression in the brainstem of
  • ovariectomized rhesus macaques. J Neuroendocrinol. 2000; 12: 899 –909.
  • - Smith S, Waterhouse B, Woodward D. Sex steroids effects on extrahypothalamic CNS I.
  • Estrogen augments neuronal responsiveness to iontophoretically applied glutamate in the
  • cerebellum. Brain Res.1987; 422: 40 –51.
  • - Woolley C, McEwen B. Estradiol mediates fluctuation in hippocampal synapse density
  • during the estrous cycle in the adult rat. J Neurosci. 1992; 12: 2549 –54.
  • - Brandes JL. The influence of estrogen on migraine: a systematic review. JAMA. 2006; 19:
  • - 30.
  • - Karlı N, Baykan B, Ertaş M, Zarifoğlu M, Siva A, Saip S, Ozkaya G, et al. Impact of sex
  • hormonal changes on tension-type headache and migraine: a cross-sectional populationbased
  • survey in 2,600 women. J Headache Pain. 2012 Oct;13(7):557-65.
  • - MacGregor EA. Migraine in pregnancy and lactation. Neurol Sci. 2014; 35: 61-4.
  • - Chen T-C, Leviton A. Headache recurrence in pregnant women with migraine. Headache.
  • ; 34: 107–10.
  • - Granella F, Sances G, Pucci E, et al. Migraine with aura and reproductive life events: a
  • case control study. Cephalalgia. 2000; 20: 701–7.
  • - Cupini LM, Matteis M, Troisi E, Calabresi P, Bernardi G, Silvestrini M Sex-hormonerelated
  • events in migrainous females. A clinical comparative study between migraine with
  • aura and migraine without aura. Cephalalgia 1995; 15: 140–4.
  • - Marcus DA. Focus on primary care diagnosis and management of headache in women.
  • Obstet Gynecol. Surv 1999; 54: 395–402.
  • - Digre KB. Headaches during pregnancy. Clin Obstet Gynecol. 2013; 56: 317-29.

GEBELİKTE İZLENEN PRİMER BAŞ AĞRILARI VE BU NEDENLE REÇETE DIŞI İLAÇ KULLANIMI

Yıl 2014, Cilt: 5 Sayı: 18, 26 - 33, 03.03.2015
https://doi.org/10.17944/mkutfd.67514

Öz

Amaç: Çalışmamızın amacı gebelik döneminde
görülen primer baş ağrılarının özelliklerini ve baş
ağrısı nedeniyle reçete dışı ilaç kullanım sıklığını
göstermektir.
Gereç ve Yöntemler: Gebelik sonrası ilk üç aydaki
350 kadının gebelik dönemindeki baş ağrıları yüz
yüze görüşmelerde nöroloji hekimi tarafından
sorgulanarak, baş ağrısı özellikleri, reçeteli ve
reçete dışı ilaç kullanımı incelendi.
Bulgular: Üç yüz elli gebenin 44’ü çeşitli
sebeplerle çalışma dışı tutuldu. Çalışmaya alınan
bireylerden 129 tanesi (%42,2’si) gebeliği boyunca
hiç baş ağrısı yaşamamıştı. Yüz yetmiş yedi
annenin (%57,8) hamilelikte primer baş ağrısına
ilişkin yakınmaları olmuştu. Primer baş ağrısından
şikayet edenlerin 44’ü (%24,8) doktora
başvurmuştu. Baş ağrısı olanların 83’ü (%46,6) ağrı
kesici ilaç kullanmış; ancak ilaç kullananların
sadece 36’sı (%43,4) doktora başvurmuştu
Sonuç: Çalışmamızdan elde edilen veriler gebelik
döneminde yaşanan baş ağrılarının kontrolsüz ilaç
kullanımına neden olması açısından da dikkate
alınması gerektiğini göstermektedir.

Kaynakça

  • - Black RA, Hill DA. Over-the-counter medications in pregnancy. Am Fam Physician.
  • ; 15: 2517-24.
  • - Tillett J, Kostich LM, VandeVusse L. Use of over-the-counter medications during
  • pregnancy. J Perinat Neonatal Nurs. 2003;17: 3-18.
  • - Melhado E, Maciel JA Jr, Guerreiro CA. Headaches during pregnancy in women with a
  • prior history of menstrual headaches. Arq Neuropsiquiatr. 2005 ;63: 934-40.
  • - Granella F, Sances G, Pucci E, et al. Migraine with aura and reproductive life events: a
  • case control study. Cephalalgia. 2000;20: 701–7.
  • - Von Wald T, Walling AD. Headache during pregnancy. Obstet Gynecol Surv. 2002; 57:
  • -85.
  • - Maggioni F, Alessi C, Maggino T, Zanchin G. Headache during pregnancy. Cephalalgia.
  • ; 17: 765- 69.
  • - Peter J Goadsby, Jay Goldberg,Stephen D Silberstein. Migraine in pregnancy. BMJ; 2008:
  • -
  • - Pahim LS, Menezes AM, Lima R. Prevalence and factors associated to migraine in adult
  • population, Southern Brazil. Rev Saude Publica. 2006; 40: 692- 98.
  • - Sarchielli P, Tognoloni M, Russo S, et al. Variations in the platelet arginine/nitric oxide
  • pathway during the ovarian cycle in females affected by menstrual migraine. Cephalalgia.
  • ; 16: 468-75.
  • - Sachdeva P, Patel BG, Patel BK. Drug use in pregnancy; a point to ponder! Indian J
  • Pharm Sci. 2009; 71: 1-7.
  • - Uhl K, Kennedy DL, Kweder SL. Information on medication use in pregnancy. Am Fam
  • Physician. 2003; 15: 2476-78.
  • - Olesen C, Steffensen FH, Nielsen GL, de Jong-van den Berg L, Olsen J, Sørensen HT.
  • Drug use in first pregnancy and lactation: a population-based survey among Danish
  • women. The EUROMAP group. Eur J Clin Pharmacol. 1999; 55: 139-44.
  • - Olesen C, Thrane N, Henriksen TB, Ehrenstein V, Olsen J. Associations between socioeconomic
  • factors and the use of prescription medication during pregnancy: a populationbased
  • study among 19,874 Danish women. Eur J Clin Pharmacol. 2006; 62: 547-53.
  • - Göbel H, Petersen-Braun M, Soyka D. The epidemiology of headache in Germany: a
  • nationwide survey of a representative sample on the basis of the headache classification of
  • the International Headache Society. Cephalalgia. 1994; 142: 97-106.
  • - Launer LJ, Terwindt GM, Ferrari MD. The prevalence and characteristics of migraine in a
  • population-based cohort: the GEM study. Neurology. 1999; 53: 537- 42.
  • - Menon R, Bushnell CD. Headache and pregnancy. Neurologist. 2008; 14: 108-19.
  • - Pau K, Hess D, Kohama S, et al. Oestrogen upregulates noradrenaline release in the
  • mediobasal hypothalamus and tyrosine hydroxylase gene expression in the brainstem of
  • ovariectomized rhesus macaques. J Neuroendocrinol. 2000; 12: 899 –909.
  • - Smith S, Waterhouse B, Woodward D. Sex steroids effects on extrahypothalamic CNS I.
  • Estrogen augments neuronal responsiveness to iontophoretically applied glutamate in the
  • cerebellum. Brain Res.1987; 422: 40 –51.
  • - Woolley C, McEwen B. Estradiol mediates fluctuation in hippocampal synapse density
  • during the estrous cycle in the adult rat. J Neurosci. 1992; 12: 2549 –54.
  • - Brandes JL. The influence of estrogen on migraine: a systematic review. JAMA. 2006; 19:
  • - 30.
  • - Karlı N, Baykan B, Ertaş M, Zarifoğlu M, Siva A, Saip S, Ozkaya G, et al. Impact of sex
  • hormonal changes on tension-type headache and migraine: a cross-sectional populationbased
  • survey in 2,600 women. J Headache Pain. 2012 Oct;13(7):557-65.
  • - MacGregor EA. Migraine in pregnancy and lactation. Neurol Sci. 2014; 35: 61-4.
  • - Chen T-C, Leviton A. Headache recurrence in pregnant women with migraine. Headache.
  • ; 34: 107–10.
  • - Granella F, Sances G, Pucci E, et al. Migraine with aura and reproductive life events: a
  • case control study. Cephalalgia. 2000; 20: 701–7.
  • - Cupini LM, Matteis M, Troisi E, Calabresi P, Bernardi G, Silvestrini M Sex-hormonerelated
  • events in migrainous females. A clinical comparative study between migraine with
  • aura and migraine without aura. Cephalalgia 1995; 15: 140–4.
  • - Marcus DA. Focus on primary care diagnosis and management of headache in women.
  • Obstet Gynecol. Surv 1999; 54: 395–402.
  • - Digre KB. Headaches during pregnancy. Clin Obstet Gynecol. 2013; 56: 317-29.
Toplam 59 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi
Bölüm Original Articles
Yazarlar

Hava Dede

Meral Uzel Bu kişi benim

İsmet Melek Bu kişi benim

Esra Okuyucu Bu kişi benim

Yayımlanma Tarihi 3 Mart 2015
Gönderilme Tarihi 2 Mart 2015
Yayımlandığı Sayı Yıl 2014 Cilt: 5 Sayı: 18

Kaynak Göster

Vancouver Dede H, Uzel M, Melek İ, Okuyucu E. GEBELİKTE İZLENEN PRİMER BAŞ AĞRILARI VE BU NEDENLE REÇETE DIŞI İLAÇ KULLANIMI. mkutfd. 2015;5(18):26-33.