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The prevalence of celiac disease in healthy school children in Van City, east of Turkey: a screening study using a rapid test

Yıl 2016, Cilt: 3 Sayı: 3, 130 - 3, 15.03.2016

Öz

Objective:  Celiac disease is seen by increasing rates in the whole world. It may have a silent course besides having classical symptoms. It may result in serious complications if the diagnosis is delayed such as anemia, fatigue, vitamin K deficiency, excessive bruising and bleeding. The aim of this study is to detect celiac patients who have not been diagnosed yet in healthy school children.

Materials and Methods:  Present study performed was in 1003 school children who are between 5-18 years old in Van city, east of Turkey. Celiac disease was investigated via rapid celiac testing (BiocardTM stick test).

Results:  Percentages of the cases, 51.2% were female and 48.8% male.  Test was positive in two (0.2%) patients. Ten (1%) patients had immunoglobulin A deficiency. In addition to these patients, one patient had been diagnosed as celiac disease beforehand.

Conclusion:  The prevalence of celiac disease in Van city, east of Turkey in our study, shows a lower prevalence than in study which performed in our country previously

 

Kaynakça

  • Husby S, Koletzko S, Korponay-Szabó IR, et al; ESPGHAN Working Group on Coeliac Disease Diagnosis; ESPGHAN Gastroenterology Committee; European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr 2012;54(1):136-160.
  • Guandalini S, Assiri A. Celiac disease: a review. JAMA Pediatr 2014;168(3):272-278.
  • Green PH, Cellier C. Celiac disease. N Engl J Med 2007;25;357(17):1731-1743.
  • Flass T, Hoffenberg E. Celiac disease. In: Sondheimer JM, Hurtado CW (eds). The NASPGHAN fellows concise review of Pediaric Gastroenterology, Hepatology and Nutrition. CCGMP, New York 2011:89-92.
  • -
  • Dalgic B, Sari S, Basturk B, Ensari A, Egritas O, Bukulmez A, Baris Z; Turkish Celiac Study Group. Prevalence of celiac disease in healthy Turkish school children. Am J Gastroenterol 2011;106(8):1512-1517.
  • Giersiepen K, Lelgemann M, Stuhldreher N, Ronfani L, Husby S, Koletzko S, Korponay-Szabó IR; ESPGHAN Working Group on Coeliac Disease Diagnosis. Accuracy of diagnostic antibody tests for coeliac disease in children: summary of an evidence report. J Pediatr Gastroenterol Nutr. 2012;54(2):229-41.
  • Mooney PD, Wong SH, Johnston AJ, Kurien M, Avgerinos A, Sanders DS. Increased Detection of Celiac Disease With Measurement of Deamidated Gliadin Peptide Antibody Before Endoscopy. Clin Gastroenterol Hepatol. 2015 Jul;13(7):1278-1284.
  • Singh P, Wadhwa N, Chaturvedi MK, Bhatia V, Saini S, Tandon N, Makharia GK, Maki M, Not T, Phillips A, Bhatnagar S. Validation of point-of-care testing for coeliac disease in children in a tertiary hospital in north India. Arch Dis Child. 2014 Nov;99(11):1004-8.
  • Mooney PD, Kurien M, Evans KE, Chalkiadakis I, Hale MF, Kannan MZ, Courtice V, Johnston AJ, Irvine AJ, Hadjivassiliou M, Sanders DS. Point-of-care testing for celiac disease has a low sensitivity in endoscopy. Gastrointest Endosc. 2014 Sep;80(3):456-62.
  • Korponay-Szabó IR, Szabados K, Pusztai J, Uhrin K, Ludmány E, Nemes E, Kaukinen K, Kapitány A, Koskinen L, Sipka S, Imre A, Mäki M. Population screening for coeliac disease in primary care by district nurses using a rapid antibody test: diagnostic accuracy and feasibility study. BMJ. 2007 Dec 15;335(7632):1244-7.
  • Pichler J, Zilbauer M, Torrente F, Heuschkel R, Phillips A, Salvestrini C. Feasibility of a finger prick-based self-testing kit in first- and second-degree relatives of children with coeliac disease. World J Gastroenterol. 2011 Apr 14;17(14):1840-3.
  • Doğan Y, Yildirmaz S, Ozercan IH. Prevalence of celiac disease among first-degree relatives of patients with celiac disease. J Pediatr Gastroenterol Nutr. 2012 Aug;55(2):205-8.
  • Popp A, Jinga M, Jurcut C, Balaban V, Bardas C, Laurila K, Vasilescu F, Ene A, Anca I, Mäki M. Fingertip rapid point-of-care test in adult case-finding in coeliac disease. BMC Gastroenterol. 2013 Jul 12;13:115.
  • Oliveira A, Trindade E, Tavares M, Lima R, Terra M, Dias JA. Celiac disease in first degree relatives of celiac children. Arq Gastroenterol. 2012 Jul-Sep;49(3):204-7.
  • Korkut E, Bektas M, Oztas E, Kurt M, Cetinkaya H, Ozden A. The prevalence of celiac disease in patients fulfilling Rome III criteria for irritable bowel syndrome. Eur J Intern Med. 2010 Oct;21(5):389-92.
  • Kansu A, Kuloğlu Z, Demir A, Yaman A; Turkish Celiac Study Group. Yield of coeliac screening in abdominal pain-associated functional gastrointestinal system disorders. J Paediatr Child Health. 2015 Nov;51(11):1066-70.
  • Alarida K, Harown J, Ahmaida A, Marinelli L, Venturini C, Kodermaz G, Tozzoli R, Mandolesi A, Bearzi I, Catassi C. Coeliac disease in Libyan children: a screening study based on the rapid determination of anti-transglutaminase antibodies. Dig Liver Dis. 2011 Sep;43(9):688-91.
  • -
  • Karakoyun M, Deviren R, Öztürk O, Genç RE, Aydoğdu S. Celiac Disease Screening on Students of the Department of Nutrition and Dietetics and Medical School at Ege University. J Pediatr Res 2015; 2: 66-9.

The prevalence of celiac disease in healthy school children in Van City, east of Turkey: a screening study using a rapid test

Yıl 2016, Cilt: 3 Sayı: 3, 130 - 3, 15.03.2016

Öz

Kaynakça

  • Husby S, Koletzko S, Korponay-Szabó IR, et al; ESPGHAN Working Group on Coeliac Disease Diagnosis; ESPGHAN Gastroenterology Committee; European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr 2012;54(1):136-160.
  • Guandalini S, Assiri A. Celiac disease: a review. JAMA Pediatr 2014;168(3):272-278.
  • Green PH, Cellier C. Celiac disease. N Engl J Med 2007;25;357(17):1731-1743.
  • Flass T, Hoffenberg E. Celiac disease. In: Sondheimer JM, Hurtado CW (eds). The NASPGHAN fellows concise review of Pediaric Gastroenterology, Hepatology and Nutrition. CCGMP, New York 2011:89-92.
  • -
  • Dalgic B, Sari S, Basturk B, Ensari A, Egritas O, Bukulmez A, Baris Z; Turkish Celiac Study Group. Prevalence of celiac disease in healthy Turkish school children. Am J Gastroenterol 2011;106(8):1512-1517.
  • Giersiepen K, Lelgemann M, Stuhldreher N, Ronfani L, Husby S, Koletzko S, Korponay-Szabó IR; ESPGHAN Working Group on Coeliac Disease Diagnosis. Accuracy of diagnostic antibody tests for coeliac disease in children: summary of an evidence report. J Pediatr Gastroenterol Nutr. 2012;54(2):229-41.
  • Mooney PD, Wong SH, Johnston AJ, Kurien M, Avgerinos A, Sanders DS. Increased Detection of Celiac Disease With Measurement of Deamidated Gliadin Peptide Antibody Before Endoscopy. Clin Gastroenterol Hepatol. 2015 Jul;13(7):1278-1284.
  • Singh P, Wadhwa N, Chaturvedi MK, Bhatia V, Saini S, Tandon N, Makharia GK, Maki M, Not T, Phillips A, Bhatnagar S. Validation of point-of-care testing for coeliac disease in children in a tertiary hospital in north India. Arch Dis Child. 2014 Nov;99(11):1004-8.
  • Mooney PD, Kurien M, Evans KE, Chalkiadakis I, Hale MF, Kannan MZ, Courtice V, Johnston AJ, Irvine AJ, Hadjivassiliou M, Sanders DS. Point-of-care testing for celiac disease has a low sensitivity in endoscopy. Gastrointest Endosc. 2014 Sep;80(3):456-62.
  • Korponay-Szabó IR, Szabados K, Pusztai J, Uhrin K, Ludmány E, Nemes E, Kaukinen K, Kapitány A, Koskinen L, Sipka S, Imre A, Mäki M. Population screening for coeliac disease in primary care by district nurses using a rapid antibody test: diagnostic accuracy and feasibility study. BMJ. 2007 Dec 15;335(7632):1244-7.
  • Pichler J, Zilbauer M, Torrente F, Heuschkel R, Phillips A, Salvestrini C. Feasibility of a finger prick-based self-testing kit in first- and second-degree relatives of children with coeliac disease. World J Gastroenterol. 2011 Apr 14;17(14):1840-3.
  • Doğan Y, Yildirmaz S, Ozercan IH. Prevalence of celiac disease among first-degree relatives of patients with celiac disease. J Pediatr Gastroenterol Nutr. 2012 Aug;55(2):205-8.
  • Popp A, Jinga M, Jurcut C, Balaban V, Bardas C, Laurila K, Vasilescu F, Ene A, Anca I, Mäki M. Fingertip rapid point-of-care test in adult case-finding in coeliac disease. BMC Gastroenterol. 2013 Jul 12;13:115.
  • Oliveira A, Trindade E, Tavares M, Lima R, Terra M, Dias JA. Celiac disease in first degree relatives of celiac children. Arq Gastroenterol. 2012 Jul-Sep;49(3):204-7.
  • Korkut E, Bektas M, Oztas E, Kurt M, Cetinkaya H, Ozden A. The prevalence of celiac disease in patients fulfilling Rome III criteria for irritable bowel syndrome. Eur J Intern Med. 2010 Oct;21(5):389-92.
  • Kansu A, Kuloğlu Z, Demir A, Yaman A; Turkish Celiac Study Group. Yield of coeliac screening in abdominal pain-associated functional gastrointestinal system disorders. J Paediatr Child Health. 2015 Nov;51(11):1066-70.
  • Alarida K, Harown J, Ahmaida A, Marinelli L, Venturini C, Kodermaz G, Tozzoli R, Mandolesi A, Bearzi I, Catassi C. Coeliac disease in Libyan children: a screening study based on the rapid determination of anti-transglutaminase antibodies. Dig Liver Dis. 2011 Sep;43(9):688-91.
  • -
  • Karakoyun M, Deviren R, Öztürk O, Genç RE, Aydoğdu S. Celiac Disease Screening on Students of the Department of Nutrition and Dietetics and Medical School at Ege University. J Pediatr Res 2015; 2: 66-9.
Toplam 20 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Araştırma Makalesi
Yazarlar

Nesrin Ceylan

Kaan Demiroren Bu kişi benim

Yayımlanma Tarihi 15 Mart 2016
Yayımlandığı Sayı Yıl 2016 Cilt: 3 Sayı: 3

Kaynak Göster

APA Ceylan, N., & Demiroren, K. (2016). The prevalence of celiac disease in healthy school children in Van City, east of Turkey: a screening study using a rapid test. Medical Science and Discovery, 3(3), 130-3. https://doi.org/10.17546/msd.53695
AMA Ceylan N, Demiroren K. The prevalence of celiac disease in healthy school children in Van City, east of Turkey: a screening study using a rapid test. Med Sci Discov. Mart 2016;3(3):130-3. doi:10.17546/msd.53695
Chicago Ceylan, Nesrin, ve Kaan Demiroren. “The Prevalence of Celiac Disease in Healthy School Children in Van City, East of Turkey: A Screening Study Using a Rapid Test”. Medical Science and Discovery 3, sy. 3 (Mart 2016): 130-3. https://doi.org/10.17546/msd.53695.
EndNote Ceylan N, Demiroren K (01 Mart 2016) The prevalence of celiac disease in healthy school children in Van City, east of Turkey: a screening study using a rapid test. Medical Science and Discovery 3 3 130–3.
IEEE N. Ceylan ve K. Demiroren, “The prevalence of celiac disease in healthy school children in Van City, east of Turkey: a screening study using a rapid test”, Med Sci Discov, c. 3, sy. 3, ss. 130–3, 2016, doi: 10.17546/msd.53695.
ISNAD Ceylan, Nesrin - Demiroren, Kaan. “The Prevalence of Celiac Disease in Healthy School Children in Van City, East of Turkey: A Screening Study Using a Rapid Test”. Medical Science and Discovery 3/3 (Mart 2016), 130-3. https://doi.org/10.17546/msd.53695.
JAMA Ceylan N, Demiroren K. The prevalence of celiac disease in healthy school children in Van City, east of Turkey: a screening study using a rapid test. Med Sci Discov. 2016;3:130–3.
MLA Ceylan, Nesrin ve Kaan Demiroren. “The Prevalence of Celiac Disease in Healthy School Children in Van City, East of Turkey: A Screening Study Using a Rapid Test”. Medical Science and Discovery, c. 3, sy. 3, 2016, ss. 130-3, doi:10.17546/msd.53695.
Vancouver Ceylan N, Demiroren K. The prevalence of celiac disease in healthy school children in Van City, east of Turkey: a screening study using a rapid test. Med Sci Discov. 2016;3(3):130-3.