Ligamentum Flavumu İnvaze Eden ve Ani Gelişen Quadriparezi ile Başvuran Primer Servikal Osteosarkom: Olgu Sunumu

Yıl 2017, Cilt: 5 Sayı: 3, 127 - 130, 27.12.2017

Numan Karaaslan Tezcan Çalışkan Abdullah Talha Şimşek

Öz

Primer servikal spinal osteosarkomlar oldukça nadir görülen patolojiler olup,
nadir olarak ligamentum flavum invazyonu yapmaktadırlar. Servikal bölgenin kompleks
anatomik yapısı nedeni ile tümöral dokunun cerrahi rezeksiyon derecesi
sınırlıdır. Bu sebeple kötü prognoza sahip tümörlerdir. Bu makalede; 63
yaşında, ani gelişen quadriparezi ile başvuran, ligamentum flavum invazyonu
yapmış primer servikal spinal osteosarkom olgusu sunulmuştur. Hastaya subtotal
kitle eksizyonu ve neoadjuvan kemoterapi uygulanmış olup, takiplerinde hastanın
şikayetleri kısmen gerilemiştir. 

Anahtar Kelimeler

Adjüvan Kemoterapi, Subtotal rezeksiyon, Onkoloji

Kaynakça

• 1- Barwick KW, Huvos AG, Smith J. Primary osteogenic sarcoma of the vertebral column. A clinicopathologic correlation of ten patients. Cancer 46:559 –604, 1980.
• 2- Campanacci M, Osteosarcoma Cervellati G. A review of 345 cases. J Orthop Traumatol 1:5 –22, 1975.
• 3- Dreghorn CR, Newman RJ, Hardy GJ, et al. Primary tumors of the axial skeleton. Experience of the Leeds Regional Bone Tumor Registry. Spine 15:137 –40, 1990.
• 4- Feng D, Yang X, Liu T, Xiao J, Wu Z, Huang Q, Ma J, Huang W, Zheng W, Cui Z, Xu H, Teng Y. Osteosarcoma of spine : surgical treatmnet and outcomes. World Jour Surg Onco. 11:89, 2013.
• 5- Gandolfi A, Bordi C. Primary Osteosarcoma of the cervical spine causing neurological sumptoms. Surg Neurol 21:441 – 4,1984.
• 6- Green R, Saifuddin A, Cannon S, et al. Pictorial review: Imaging of primary osteosarcoma of the spine. Clin Radiol 51:325 – 9, 1996.
• 7- llaslan H, Sundaram M, Unni KK, et al. Primary vertebral osteosarcoma: imaging findings. Radiology 230:697 –702, 2004.
• 8- Ozaki T, Flege S, Liljenqvist U, Hillmann A, Delling G, Salzer-Kuntschik M, Jürgens H, Kotz R, Winkelmann W, Bielack SS: Osteosarcoma of the spine: experience of the Cooperative Osteosarcoma Study Group. Cancer 94(4):1069–1077, 2002.
• 9- Sansur CA, Pouratian N, Dumont AS, et al. Part II: Spinal-cord neoplasms: primary tumors of the bony spine and adjacent soft tissues. Lancet Oncol 8:137 – 47, 2007.
• 10- Schoenfeld AJ, Hornicek FJ, Pedlow FX. Osteosarcoma of the spine: experience in 26 patients treated at the Massachusetts General Hospital. Spine J 10:708–14, 2010.
• 11- Shives TC, Dahlin DC, Sim FH, Pritchard DJ, Earle JD: Osteosarcoma of the spine. J Bone Joint Surg Am 68(5):660–668, 1986.
• 12- Stephen N Ponnampalam, Wilkinson YJ Tan, Nayyer Naveed Wazir, John George. Unusual cause of neuropathy: extensive dural spread of primary cervical osteosarcom. Acta Radiologica Short Reports. 1:6, 2012.