Öz
Çocuklarda akut tonsillofarenjitin en yaygın bakteriyel etkeni A grubu beta hemolitik streptokoktur. Eritrojenik ekzotoksinler üreten A grubu beta hemolitik streptokok suşları kızıl olarak bilinen tipik bir döküntülü hastalık oluşturur. Komplikasyonları iyi tanımlanmıştır. Hepatit nadir bir komplikasyonudur. Burada, 7 yaşında kızıl olan ve karaciğer enzimleri yükselmiş bir kız hasta sunulmuştur. Hepatite yol açan virüsler gösterilememiştir. Boğaz kültüründe A grubu beta hemolitik streptokok üremiştir. A grubu beta hemolitik streptokok enfeksiyonlarında hepatit gelişebileceği göz ardı edilmemelidir.
Anahtar Kelimeler
Kaynakça
- Steer AC, Danchin MH, Carapetis JR. Group A streptococcal infections in children. J Paediatr Child Health 2007;43:203-13.
- Wong SSY, Yuen KY. Streptococcus pyogenes and re-emergence of scarlet fever as a public health problem. Emerging Microbes & Infections 2012;1:e2;doi:10.1038/emi.2012.9 Published online 11 July 2012
- Gutiérrez Junquera C, Escudero Canto MC, Ruiz Cano R, Cuartero del Pozo I, Gil Pons E. Cholestatic hepatitis as initial manifestation of scarlet fever. An Pediatr (Barc) 2003;59:193–4.
- Gómez-Carrasco JA, Lassaletta A, Ruano D. Acute hepatitis may form part of scarlet fever. An Pediatr (Barc) 2004;60:382–3.
- Gidaris D, Zafeiriou D, Mavridis P, Gombakis N. Scarlet fever and hepatitis: A case report. Hippokratia 2008;12:186–7.
- Girisch M, Heininger U. Scarlet fever associated with hepatitis-A report of two cases. Infection 2000; 28:251–3.
- Elishkewitz K, Shapiro R, Amir J, Nussinovitch M. Hepatitis in scarlet fever. Isr Med Assoc J 2004;6:569-70.
- Norrby-Teglund A, Chatellier S, Low DE, McGeer A, Green K, Kotb M. Host variations in cytokine responses to superantigens determine the severity of invasive group A streptococcal infection. Eur J Immunol 2000;30:3247-55.
- Brody H, Smith LW. The visceral pathology in scarlet fever and the related Streptococcus infections. Amer J Path 1936;12:373- 394.5.
- Stevens DL. Streptococcal toxic-shock syndrome: Spectrum of disease, pathogenesis, and new concepts in treatment. Emerg Infect Dis 1995;1:69-78.
- Mcmahon HE, Mallry FB. Streptococcus hepatitis. Am J Pathol 1931;7:299-325.
- Kocak N, Ozsoylu S, Ertugrul M, Ozdol G. Liver damage in scarlet fever. Descriptions of two affected children. Clin Pediatr (Phila) 1976;15:462-4.
- Robbens E, De Man M, Schurgers M, Boelaert J, Lameire N. Systemic complications of streptococcal scarlet fever: Two case reports and a review of the literature. Acta Clin Belg 1986;41: 311-8.
- Jansen TL, Janssen M, de Jong AJ, Jeurissen ME. Post strep- tococcal reactive arthritis: A clinical and serological description, revealing its distinction from acute rheumatic fever. J Intern Med 1999;245:261-7.
- Demers B, Simor AE, Vellend H, Schlievert PM, Byrne S, Jamieson F, et al. Severe invasive group A streptococcal infections in Ontario, Canada: 1987-1991. Clin Infect Dis 1993;16:792-800.
Öz
The most common cause of tonsillopharyngitis is group A beta hemolytic streptococcal infection in children. Group A beta hemolytic streptococcus strains that produce erythrogenic exotoxins cause a typical exanthematous disease called scarlet fever. Complications are well described. Hepatitis is a rare complication. We present a 7-year old girl with scarlet fever and elevated liver transaminases in this report. Viruses that lead to hepatitis were not demonstrated. Group A beta hemolytic streptococcus was isolated from the throat culture of the patient. Hepatitis should not be overlooked in patients with group A beta hemolytic streptococcal infections
Anahtar Kelimeler
Kaynakça
- Steer AC, Danchin MH, Carapetis JR. Group A streptococcal infections in children. J Paediatr Child Health 2007;43:203-13.
- Wong SSY, Yuen KY. Streptococcus pyogenes and re-emergence of scarlet fever as a public health problem. Emerging Microbes & Infections 2012;1:e2;doi:10.1038/emi.2012.9 Published online 11 July 2012
- Gutiérrez Junquera C, Escudero Canto MC, Ruiz Cano R, Cuartero del Pozo I, Gil Pons E. Cholestatic hepatitis as initial manifestation of scarlet fever. An Pediatr (Barc) 2003;59:193–4.
- Gómez-Carrasco JA, Lassaletta A, Ruano D. Acute hepatitis may form part of scarlet fever. An Pediatr (Barc) 2004;60:382–3.
- Gidaris D, Zafeiriou D, Mavridis P, Gombakis N. Scarlet fever and hepatitis: A case report. Hippokratia 2008;12:186–7.
- Girisch M, Heininger U. Scarlet fever associated with hepatitis-A report of two cases. Infection 2000; 28:251–3.
- Elishkewitz K, Shapiro R, Amir J, Nussinovitch M. Hepatitis in scarlet fever. Isr Med Assoc J 2004;6:569-70.
- Norrby-Teglund A, Chatellier S, Low DE, McGeer A, Green K, Kotb M. Host variations in cytokine responses to superantigens determine the severity of invasive group A streptococcal infection. Eur J Immunol 2000;30:3247-55.
- Brody H, Smith LW. The visceral pathology in scarlet fever and the related Streptococcus infections. Amer J Path 1936;12:373- 394.5.
- Stevens DL. Streptococcal toxic-shock syndrome: Spectrum of disease, pathogenesis, and new concepts in treatment. Emerg Infect Dis 1995;1:69-78.
- Mcmahon HE, Mallry FB. Streptococcus hepatitis. Am J Pathol 1931;7:299-325.
- Kocak N, Ozsoylu S, Ertugrul M, Ozdol G. Liver damage in scarlet fever. Descriptions of two affected children. Clin Pediatr (Phila) 1976;15:462-4.
- Robbens E, De Man M, Schurgers M, Boelaert J, Lameire N. Systemic complications of streptococcal scarlet fever: Two case reports and a review of the literature. Acta Clin Belg 1986;41: 311-8.
- Jansen TL, Janssen M, de Jong AJ, Jeurissen ME. Post strep- tococcal reactive arthritis: A clinical and serological description, revealing its distinction from acute rheumatic fever. J Intern Med 1999;245:261-7.
- Demers B, Simor AE, Vellend H, Schlievert PM, Byrne S, Jamieson F, et al. Severe invasive group A streptococcal infections in Ontario, Canada: 1987-1991. Clin Infect Dis 1993;16:792-800.
Ayrıntılar
| Diğer ID | JA66YN47YP |
|---|---|
| Bölüm | Case Report |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Haziran 2015 |
| Gönderilme Tarihi | 1 Haziran 2015 |
| Yayımlandığı Sayı | Yıl 2015 Cilt: 9 Sayı: 2 |