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Current review of biodegradation and detoxification strategies for zearalenone contaminated food and feed

Yıl 2024, Cilt: 11 Sayı: 1, 157 - 168, 05.02.2024
https://doi.org/10.21448/ijsm.1271127

Öz

Mycotoxins are toxic metabolites produced by fungi that may cause serious health problems in humans and animals. Zearalenone is an estrogenic mycotoxin produced by Fusarium species that leads to huge economic losses in the food industry and livestock husbandry. Contamination of food and feed with zearalenone has reproductive problems, carcinogenicity, immunotoxicity, and other cytotoxic effects. At present, microorganisms and enzymes derived from microbial strains have been widely used for the degradation of zearalenone in food and feed. Researchers have developed biodegradation of zearalenone by the use of microbial and their enzyme derivatives, which offers harmless products and is environmentally friendly. Development of recombinant enzymes improves enzymatic detoxification of zearalenone to a non-toxic product without damaging the nutritional content. This review summarizes biodegradation and detoxification strategies of zearalenone using microorganisms and enzyme derivatives to nontoxic products.

Kaynakça

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  • Ahn, J.Y., Kim, J., Cheong, D.H., Hong, H., Jeong, J.Y., & Kim, B.G. (2022). An In Vitro Study on the Efficacy of Mycotoxin Sequestering Agents for Aflatoxin B1, Deoxynivalenol, and Zearalenone. Animals, 12(3), 333. https://doi.org/10.3390/ani12030333
  • Arroyo-Manzanares, N., Campillo, N., López-García, I., Hernández-Córdoba, M., & Viñas, P. (2021). High-Resolution mass spectrometry for the determination of mycotoxins in biological samples. A review. Microchemical Journal, 166, 106197. https://doi.org/10.1016/j.microc.2021.106197
  • Azam, M.S., Yu, D., Liu, N., & Wu, A. (2019). Degrading ochratoxin A and zearalenone mycotoxins using a multifunctional recombinant enzyme. Toxins, 11(5), 301. https://doi.org/10.3390/toxins11050301
  • Bergman, A., Wenning, L., Siewers, V., & Nielsen, J. (2018). Investigation of putative regulatory acetylation sites in Fas2p of Saccharomyces cerevisiae. bioRxiv, 430918. https://doi.org/10.1101/430918
  • Bi, K, Zhang, W., Xiao, Z., & Zhang. D. (2018). Characterization, expression and application of a zearalenone degrading enzyme from Neurospora crassa. AMB Express, 8, 194. https://doi.org/10.1186/s13568-018-0723-z
  • Bin, Y.S., Zheng, H.C., Xu, J.Y., Zhao, X.Y., Shu, W.J., Li, X.M., Song, H., & Ma, Y.H. (2021). New biotransformation mode of zearalenone identifed in Bacillus subtilis Y816 revealing a novel ZEN conjugate. Journal of Agricultural and Food Chemistry, 69(26), 7409–7419. https://doi.org/10.1021/acs.jafc.1c01817
  • Bouajila, A., Lamine, M., Hamdi, Z., Ghorbel, A., & Gangashetty, P. (2022). A Nutritional Survey of Local Barley Populations Based on the Mineral Bioavailability, Fatty Acid Profile, and Geographic Distribution of Fusarium Species and the Mycotoxin Zearalenone (ZEN). Agronomy, 12(4), 916. https://doi.org/10.3390/agronomy12040916
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  • Chen, S., Pan, L., Liu, S., Pan, L., Li, X., & Wang, B. (2021). Recombinant expression and surface display of a zearalenone lactonohydrolase from Trichoderma aggressivum in Escherichia coli. Protein Expression and Purification, 187, 105933. https://doi.org/10.1016/j.pep.2021.105933
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Current review of biodegradation and detoxification strategies for zearalenone contaminated food and feed

Yıl 2024, Cilt: 11 Sayı: 1, 157 - 168, 05.02.2024
https://doi.org/10.21448/ijsm.1271127

Öz

Mycotoxins are toxic metabolites produced by fungi that may cause serious health problems in humans and animals. Zearalenone is an estrogenic mycotoxin produced by Fusarium species that leads to huge economic losses in the food industry and livestock husbandry. Contamination of food and feed with zearalenone has reproductive problems, carcinogenicity, immunotoxicity, and other cytotoxic effects. At present, microorganisms and enzymes derived from microbial strains have been widely used for the degradation of zearalenone in food and feed. Researchers have developed biodegradation of zearalenone by the use of microbial and their enzyme derivatives, which offers harmless products and is environmentally friendly. Development of recombinant enzymes improves enzymatic detoxification of zearalenone to a non-toxic product without damaging the nutritional content. This review summarizes biodegradation and detoxification strategies of zearalenone using microorganisms and enzyme derivatives to nontoxic products.

Kaynakça

  • Adunphatcharaphon, S., Petchkongkaew, A., & Visessanguan, W. (2021). In vitro mechanism assessment of zearalenone removal by plant-derived Lactobacillus plantarum BCC 47723. Toxins, 13, 286. https://doi.org/10.3390/toxins13040286
  • Ahn, J.Y., Kim, J., Cheong, D.H., Hong, H., Jeong, J.Y., & Kim, B.G. (2022). An In Vitro Study on the Efficacy of Mycotoxin Sequestering Agents for Aflatoxin B1, Deoxynivalenol, and Zearalenone. Animals, 12(3), 333. https://doi.org/10.3390/ani12030333
  • Arroyo-Manzanares, N., Campillo, N., López-García, I., Hernández-Córdoba, M., & Viñas, P. (2021). High-Resolution mass spectrometry for the determination of mycotoxins in biological samples. A review. Microchemical Journal, 166, 106197. https://doi.org/10.1016/j.microc.2021.106197
  • Azam, M.S., Yu, D., Liu, N., & Wu, A. (2019). Degrading ochratoxin A and zearalenone mycotoxins using a multifunctional recombinant enzyme. Toxins, 11(5), 301. https://doi.org/10.3390/toxins11050301
  • Bergman, A., Wenning, L., Siewers, V., & Nielsen, J. (2018). Investigation of putative regulatory acetylation sites in Fas2p of Saccharomyces cerevisiae. bioRxiv, 430918. https://doi.org/10.1101/430918
  • Bi, K, Zhang, W., Xiao, Z., & Zhang. D. (2018). Characterization, expression and application of a zearalenone degrading enzyme from Neurospora crassa. AMB Express, 8, 194. https://doi.org/10.1186/s13568-018-0723-z
  • Bin, Y.S., Zheng, H.C., Xu, J.Y., Zhao, X.Y., Shu, W.J., Li, X.M., Song, H., & Ma, Y.H. (2021). New biotransformation mode of zearalenone identifed in Bacillus subtilis Y816 revealing a novel ZEN conjugate. Journal of Agricultural and Food Chemistry, 69(26), 7409–7419. https://doi.org/10.1021/acs.jafc.1c01817
  • Bouajila, A., Lamine, M., Hamdi, Z., Ghorbel, A., & Gangashetty, P. (2022). A Nutritional Survey of Local Barley Populations Based on the Mineral Bioavailability, Fatty Acid Profile, and Geographic Distribution of Fusarium Species and the Mycotoxin Zearalenone (ZEN). Agronomy, 12(4), 916. https://doi.org/10.3390/agronomy12040916
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  • Chen, S., Pan, L., Liu, S., Pan, L., Li, X., & Wang, B. (2021). Recombinant expression and surface display of a zearalenone lactonohydrolase from Trichoderma aggressivum in Escherichia coli. Protein Expression and Purification, 187, 105933. https://doi.org/10.1016/j.pep.2021.105933
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  • Ju, J., Tinyiro, S.E., Yao, W., Yu, H., Guo, Y., Qian, H., & Xie, Y. (2019). The ability of Bacillus subtilis and Bacillus natto to degrade zearalenone and its application in food. Journal of Food Processing and Preservation, 43(10), e14122. https://doi.org/10.1111/jfpp.14122
  • Juodeikiene, G., Bartkiene, E., Cernauskas, D., Cizeikiene, D., Zadeike, D., Lele, V., & Bartkevics, V. (2018). Antifungal activity of lactic acid bacteria and their application for Fusarium mycotoxin reduction in malting wheat grains. LWT, 89, 307–314. https://doi.org/10.1016/j.lwt.2017.10.061.
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  • Keller, L., Abrunhosa, L., Keller, K., Rosa, C.A., Cavaglieri, L., & Venâncio, A. (2015). Zearalenone and its derivatives α-zearalenol and β-zearalenol decontamination by Saccharomyces cerevisiae strains isolated from bovine forage. Toxins, 7(8), 3297-3308. https://doi.org/10.3390/toxins7083297
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  • Loi, M., Fanelli, F., Liuzzi, V.C., Logrieco, A.F., & Mulè, G. (2017). Mycotoxin biotransformation by native and commercial enzymes: Present and future perspectives. Toxins, 9(4), 111. https://doi.org/10.3390/toxins9040111
  • Luo, Y., Liu, X., Yuan, L., & Li, J. (2020). Complicated interactions between bio-adsorbents and mycotoxins during mycotoxin adsorption: Current research and future prospects. Trends in Food Science & Technology, 96, 127-134. https://doi.org/10.1016/j.tifs.2019.12.012
  • Møller, C.O. de A., Freire, L., Rosim, R.E., Margalho, L.P., Balthazar, C.F., Franco, L.T., Sant’Ana, A. de S., Corassin, C.H., Rattray, F.P., & Oliveira, C.A.F. de. (2021). Effect of Lactic Acid Bacteria Strains on the Growth and Aflatoxin Production Potential of Aspergillus parasiticus, and Their Ability to Bind Aflatoxin B1, Ochratoxin A, and Zearalenone in vitro. Frontiers in Microbiology, 12. https://doi.org/10.3389/fmicb.2021.655386
  • Nahle, S., El Khoury, A., Savvaidis, I., Chokr, A., Louka, N., & Atoui, A. (2022). Detoxification approaches of mycotoxins: by microorganisms, biofilms and enzymes. International Journal of Food Contamination, 9(1), 1-14. https://doi.org/10.1186/s40550-022-00089-2
  • Navale, V.D., & Vamkudoth, K. (2022). Toxicity and preventive approaches of Fusarium derived mycotoxins using lactic acid bacteria: state of the art. Biotechnology Letters, 1-16. https://doi.org/10.1007/s10529-022-03293-4
  • Pan, Y., Liu, C., Yang, J., & Tang, Y. (2022). Conversion of zearalenone to β-zearalenol and zearalenone-14, 16-diglucoside by Candida parapsilosis ATCC 7330. Food Control, 131, 108429. https://doi.org/10.1016/j.foodcont.2021.108429
  • Qin, X., Xin, Y., Su, X., Wang, X., Wang, Y., Zhang, J., Tu, T., Yao, B., Luo, H., & Huang, H. (2021). Efficient degradation of zearalenone by dyedecolorizing peroxidase from streptomyces thermocarboxydus combining catalytic properties of manganese peroxidase and laccase. Toxins (Basel) 13, 602. https://doi.org/10.3390/toxins13090602
  • Ragoubi, C., Quintieri, L., Greco, D., Mehrez, A., Maatouk, I., D’Ascanio, V., Landoulsi, A., & Avantaggiato, G. (2021). Mycotoxin removal by Lactobacillus spp. and their application in animal liquid feed. Toxins, 13(3), 185. https://doi.org/10.3390/toxins13030185
  • Rogowska, A., Pomastowski, P., Sagandykova, G., & Buszewski, B. (2019). Zearalenone and its metabolites: Effect on human health, metabolism and neutralisation methods. Toxicon, 162, 46-56. https://doi.org/10.1016/j.toxicon.2019.03.004
  • Ropejko, K., & Twarużek, M. (2021). Zearalenone and its metabolites—general overview, occurrence, and toxicity. Toxins, 13(1), 35. https://doi.org/10.3390/toxins13010035
  • Singh, K., & Kumari, A. (2022). Traditional Mycotoxins and Their Health Implications. Mycotoxins and Mycotoxicoses, 27-64. https://doi.org/10.1007/978-981-19-2370-8_3
  • Song, Y., Wang, Y., Guo, Y., Qiao, Y., Ma, Q., Ji, C., & Zhao, L. (2021). Degradation of zearalenone and aflatoxin B1 by Lac2 from Pleurotus pulmonarius in the presence of mediators. Toxicon, 201, 1-8. https://doi.org/10.1016/j.toxicon.2021.08.003
  • Średnicka, P., Juszczuk-Kubiak, E., Wójcicki, M., Akimowicz, M., & Roszko, M. (2021). Probiotics as a biological detoxification tool of food chemical contamination: A review. Food and Chemical Toxicology, 153, 112306. https://doi.org/10.1016/j.fct.2021.112306
  • Tang, Y., Liu, C., Yang, J., & Peng, X. (2022). A novel enzyme synthesized by Acinetobacter sp. SM04 is responsible for zearalenone biodegradation. Bioscience, Biotechnology, and Biochemistry, 86, 209–216. https://doi.org/10.1093/bbb/zbab204
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  • Vega, M.F., Dieguez, S.N., Riccio, B., Aranguren, S., Giordano, A., Denzoin, L., Soraci, A.L., Tapia, M.O., Ross, R., Apás, A., & González, S.N. (2017). Zearalenone adsorption capacity of lactic acid bacteria isolated from pigs. Brazilian Journal of Microbiology, 48, 715-723. https://doi.org/10.1016/j.bjm.2017.05.001
  • Wang, G., Yu, M., Dong, F., Shi, J., & Xu, J. (2017). Esterase activity inspired selection and characterization of zearalenone degrading bacteria Bacillus pumilus ES-21. Food Control, 77, 57-64. https://doi.org/10.1016/j.foodcont.2017.01.021
  • Wang, J., & Xie, Y. (2020). Review on microbial degradation of zearalenone and aflatoxins. Grain & Oil Science and Technology, 3(3), 117 125. http://dx.doi.org/10.1016/j.gaost.2020.05.002
  • Wang, J.Q., Yang, F., Yang, P.L., Liu, J., & Lv, Z.H. (2018). Microbial reduction of zearalenone by a new isolated Lysinibacillus sp. ZJ-2016-1. World Mycotoxin Journal, 11(4), 571-578. https://doi.org/10.3920/WMJ2017.2264
  • Wang, M., Yin, L., Hu, H., Selvaraj, J.N., Zhou, Y., & Zhang, G. (2018). Expression, functional analysis and mutation of a novel neutral zearalenone-degrading enzyme. International Journal of Biological Macromolecules, 118, 1284 1292. https://doi.org/10.1016/j.ijbiomac.2018.06.111
  • Wang, N., Wu, W., Pan, J., & Long, M. (2019). Detoxification strategies for zearalenone using microorganisms: A review. Microorganisms, 7(7), 208. https://doi.org/10.3390/microorganisms7070208
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  • Xiang, L., Wang, Q., Zhou, Y., Yin, L., Zhang, G., & Ma, Y. (2016). High-level expression of a ZEN-detoxifying gene by codon optimization and biobrick in Pichia pastoris. Microbiological Research, 193, 48–56. https://doi.org/10.1016/j.micres.2016.09.004
  • Xu, H., Wang, L., Sun, J., Wang, L., Guo, H., Ye, Y., & Sun, X. (2022). Microbial detoxification of mycotoxins in food and feed. Critical Reviews in Food Science and Nutrition, 62(18), 4951-4969. https://doi.org/10.1080/10408398.2021.1879730
  • Xu, J., Wang, H., Zhu, Z., Ji, F., Yin, X., Hong, Q., & Shi, J. (2016). Isolation and characterization of Bacillus amyloliquefaciens ZDS-1: Exploring the degradation of Zearalenone by Bacillus spp. Food Control, 68, 244 250. https://doi.org/10.1016/j.foodcont.2016.03.030
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  • Yang, S.B., Zheng, H.C., Xu, J.Y., Zhao, X.Y., Shu, W.J., Li, X.M., Song, H., & Ma, Y.H. (2021). New biotransformation mode of zearalenone identified in Bacillus subtilis Y816 revealing a novel ZEN conjugate. Journal of Agricultural and Food Chemistry, 69(26), 7409-7419. https://doi.org/10.1021/acs.jafc.1c01817
  • Yang, W.C., Hsu, T.C., Cheng, K.C., & Liu, J.R. (2017). Expression of the Clonostachys rosea lactonohydrolase gene by Lactobacillus reuteri to increase its zearalenone-removing ability. Microbial Cell Factories, 16(1), 1-11. https://doi.org/10.1186/s12934-017-0687-8
  • Yli-Mattila, T., Yörü, E., Abbas, A., & Teker, T. (2022). Overview on Major Mycotoxins Accumulated on Food and Feed. Fungal Biotechnology Prospects and Avenues, 310–343. https://doi.org/10.1201/9781003248316-16
  • Yu, Y., Wu, H., Tang, Y., & Qiu, L. (2012). Cloning, expression of a peroxiredoxin gene from Acinetobacter sp. SM04 and characterization of its recombinant protein for zearalenone detoxification. Microbiological Research, 167(3), 121 126. https://doi.org/10.1016/j.micres.2011.07.004
  • Zhou, J., Zhu, L., Chen, J., Wang, W., Zhang, R., Li, Y., Zhang, Q., & Wang, W. (2020). Degradation mechanism for Zearalenone ring-cleavage by Zearalenone hydrolase RmZHD: A QM/MM study. Science of the Total Environment, 709, 135897. https://doi.org/10.1016/J.SCITOTENV.2019.135897
  • Zhu, Y., Drouin, P., Lepp, D., Li, X.Z., Zhu, H., Castex, M., & Zhou, T. (2021). A Novel Microbial Zearalenone Transformation through Phosphorylation. Toxins, 13(5), 294. https://doi.org/10.3390/toxins13050294
Toplam 71 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Yapısal Biyoloji
Bölüm Makaleler
Yazarlar

Jiregna Garı 0000-0001-5363-1023

Yayımlanma Tarihi 5 Şubat 2024
Gönderilme Tarihi 26 Mart 2023
Yayımlandığı Sayı Yıl 2024 Cilt: 11 Sayı: 1

Kaynak Göster

APA Garı, J. (2024). Current review of biodegradation and detoxification strategies for zearalenone contaminated food and feed. International Journal of Secondary Metabolite, 11(1), 157-168. https://doi.org/10.21448/ijsm.1271127
International Journal of Secondary Metabolite
e-ISSN: 2148-6905