The effects of copper- and levonorgestrel-intrauterine devices on cervical cytology

Yıl 2019, Cilt: 3 Sayı: 1, 31 - 39, 25.02.2019

Demet Kokanalı Serap Akbay Müzeyyen Gülnur Özakşit

https://doi.org/10.33716/bmedj.501014

Cited By: 1

Öz

Objective: To investigate whether there is any change in cervical
cytology before and after Copper- and Levonorgestrel-Intrauterine device (IUD)
insertion.

Material and Methods: Pap smear results before and after Copper- and
Levonorgestrel-IUD were evaluated retrospectively. All of the study specimens
consisted of conventional Pap smear samples.

Results: Among the women included in the study, 52 of them were inserted
copper- and 24  levonorgestrel-IUD. All
women had normal cytological examination results prior to IUD. There were no
cases of atypia or cancer in the two groups after IUD. Non-specific
inflammatory changes in 20 women (38.5%) and ASC-US in 6 women (11.5%) were
found in the copper-IUD group, whereas 10 (41.7%) and 3 (12.5%) women were
present in the levonorgestrel -UD group, respectively. There was no
statistically significant difference between the two groups in terms of Pap
smear results after IUD insertion.

Conclusion: Copper- and levonorgestrel-IUD do not cause neoplasia. But
they may lead to similar inflammatory changes on endometrial and cervical
cells.

Anahtar Kelimeler

copper, levonorgestrel, intrauterine device, smear

Bakırlı ve levonorgestrelli rahim içi araçların servikal sitolojiye etkileri

Öz

Amaç: Bakırlı ve levonorgestrelli Rahim içi araç (RİA) uygulanan
kadınlarda, RİA uygulaması öncesi ve sonrası servikal sitolojide herhangi bir
değişiklik olup olmadığını araştırmak

Gereç ve Yöntemler: Bakırlı ve levonorgestrelli RİA uygulanan
kadınların, RİA öncesi ve sonrası Pap smear sonuçları retrospektif olarak
incelenmiştir. Çalışma preparatlarının tamamı konvansiyonel Pap smear
örneklerinden oluşmuştur.

Bulgular: Çalışmaya dahil edilen kadınların 52 tanesine bakırlı, 24
tanesine levonorgestrelli RİA uygulanmıştır. Tüm kadınlar RİA öncesi normal
sitolojik inceleme sonucuna sahipti. RİA sonrası örneklerde, İki grupta da
atipi ya da kanser olgusuna rastlanmadı. Bakırlı RİA grubunda 20 kadında
(38.5%) non-spesifik inflamatuar değişiklik ve 6 kadında (11.5%) ASC-US
mevcutken,  levonorgestrelli RİA grubunda
bu sayılar sırasıyla 10 (41.7%) ve 3 (12.5%) idi. İki grup arasında RİA
uygulaması sonrası Pap smear sonuçları açısından istatistiksel olarak anlamlı
bir fark yoktu.

Sonuç: Bakırlı ve levonorgestrelli RİA kullanımı neoplazi gelişimine
neden olmaz. Fakat endometrial ve servikal hücreler üzerinde bir takım benzer
inflamatuar değişiklikler yapabilirler.

Anahtar Kelimeler

bakır, levonorgestrel, rahim içi araç, smear

Kaynakça

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