Year 2017, Volume 13, Issue 4, Pages 943 - 947 2017-12-29

Characterization and in vitro Evolution of Antibacterial Efficacy of Novel Hesperidin Microemulsion

Çinel Köksal Karayıldırım [1]

185 582

Natural products used in the traditional systems of medicine exhibit a various and promising resource in human health. However, these products are often characterized for their chemical composition as well as mechanisms of action. Considering the bacterial infections play an important role in human diseases, it is necessary to develop new antibacterial herbal products. The aim of this study was to isolation and structural identification of hesperidin from Citrus sinensis L. and to formulate hesperidin loaded to water-in-oil (w/o) microemulsion as an inovative formulation for bactericidal treatment. This present study indicates that hesperidin microemulsion has antibacterial activity against various types of bacteria according to MIC method. All strains were showed logaritmic reduction. These findings indicated that the microemulsion as a drug carrier, especially hesperidin formulation, may be used as an effective antibacterial therapy.

Citrus sinensis, Hesperidin, Antibacterial activity, Microemulsion, MIC
  • [1] Shakeri A., Amirhossein Sahebkar A., Behjat J., Melissa officinalis L. – A review of its traditional uses, phytochemistry and pharmacology, Journal of Ethnopharmacology, 2016, 188, 204-228.
  • [2] World Health Organization, WHO, Traditional Medicine Strategy Document 2003. Geneva, Switzerland.
  • [3] Newman D.J. and Cragg G.M. Natural products as sources of new drugs over the last 25 years, Journal of Natural Products, 2007, 70, 3, 461-477.
  • [4] Moteetee A. and Kose L.S., Medicinal plants used in Lesotho for treatment of reproductive and post reproductive problems, Journal of Ethnopharmacology, 2016, 194, 827-849.
  • [5] Omwenga E.O., Hensel A., Shitandi A., Goycoolea F.M. Ethnobotanical survey of traditionally used medicinal plants for infections of skin, gastrointestinal tract, urinary tract and the oral cavity in Borabu sub-county, Nyamira county, Kenya, Journal of Ethnopharmacology, 2015, 24, 508-514.
  • [6] Muhammad A.A., Amir H.K., Muhammad A., Izatullah I. Traditional uses of medicinal plants reported by the indigenous communities and local herbal practitioners of Bajaur Agency, Federally Administrated Tribal Areas, Pakistan, Journal of Ethnopharmacology, 2017, 198, 268-281.
  • [7] İnce İ., Kayalar H., Elgin G., Köksal Ç., Yavaşoğlu K.N.Ü. Antioxidant, Anti-inflammatory Activities and Acute Toxicity of the Polyherbal Formulation: Romix®, Pharmaceutical Biology, 2012, 50, 720-726.
  • [8] Mahmoudi S., Khali M., Benkhaled A., Benamirouche K., Baiti I. Phenolic and flavonoid contents, antioxidant and antimicrobial activities of leaf extracts from ten Algerian Ficus carica L. Varieties, Asian Pacific Journal of Tropical Biomedicine, 2016, 6, 239-245.
  • [9] Halfon B. Natural Products, Boğaziçi University Printhouse Lecture notes, 2005, (ISBN: 975.518.251.9). Turkey.
  • [10] Robards, K. and Antolovich, M. Analytical Chemistry of Fruit Bioflavonoids A Review, Analyst, 1997, 122, 11R-34R.
Subjects Engineering
Journal Section Articles
Authors

Author: Çinel Köksal Karayıldırım (Primary Author)

Dates

Publication Date: December 29, 2017

Bibtex @research article { cbayarfbe370370, journal = {Celal Bayar University Journal of Science}, issn = {1305-130X}, eissn = {1305-1385}, address = {Celal Bayar University}, year = {2017}, volume = {13}, pages = {943 - 947}, doi = {10.18466/cbayarfbe.370370}, title = {Characterization and in vitro Evolution of Antibacterial Efficacy of Novel Hesperidin Microemulsion}, key = {cite}, author = {Köksal Karayıldırım, Çinel} }
APA Köksal Karayıldırım, Ç . (2017). Characterization and in vitro Evolution of Antibacterial Efficacy of Novel Hesperidin Microemulsion. Celal Bayar University Journal of Science, 13 (4), 943-947. DOI: 10.18466/cbayarfbe.370370
MLA Köksal Karayıldırım, Ç . "Characterization and in vitro Evolution of Antibacterial Efficacy of Novel Hesperidin Microemulsion". Celal Bayar University Journal of Science 13 (2017): 943-947 <http://dergipark.org.tr/cbayarfbe/issue/33464/370370>
Chicago Köksal Karayıldırım, Ç . "Characterization and in vitro Evolution of Antibacterial Efficacy of Novel Hesperidin Microemulsion". Celal Bayar University Journal of Science 13 (2017): 943-947
RIS TY - JOUR T1 - Characterization and in vitro Evolution of Antibacterial Efficacy of Novel Hesperidin Microemulsion AU - Çinel Köksal Karayıldırım Y1 - 2017 PY - 2017 N1 - doi: 10.18466/cbayarfbe.370370 DO - 10.18466/cbayarfbe.370370 T2 - Celal Bayar University Journal of Science JF - Journal JO - JOR SP - 943 EP - 947 VL - 13 IS - 4 SN - 1305-130X-1305-1385 M3 - doi: 10.18466/cbayarfbe.370370 UR - https://doi.org/10.18466/cbayarfbe.370370 Y2 - 2017 ER -
EndNote %0 Celal Bayar University Journal of Science Characterization and in vitro Evolution of Antibacterial Efficacy of Novel Hesperidin Microemulsion %A Çinel Köksal Karayıldırım %T Characterization and in vitro Evolution of Antibacterial Efficacy of Novel Hesperidin Microemulsion %D 2017 %J Celal Bayar University Journal of Science %P 1305-130X-1305-1385 %V 13 %N 4 %R doi: 10.18466/cbayarfbe.370370 %U 10.18466/cbayarfbe.370370
ISNAD Köksal Karayıldırım, Çinel . "Characterization and in vitro Evolution of Antibacterial Efficacy of Novel Hesperidin Microemulsion". Celal Bayar University Journal of Science 13 / 4 (December 2017): 943-947. https://doi.org/10.18466/cbayarfbe.370370
AMA Köksal Karayıldırım Ç . Characterization and in vitro Evolution of Antibacterial Efficacy of Novel Hesperidin Microemulsion. Celal Bayar Univ J Sci. 2017; 13(4): 943-947.
Vancouver Köksal Karayıldırım Ç . Characterization and in vitro Evolution of Antibacterial Efficacy of Novel Hesperidin Microemulsion. Celal Bayar University Journal of Science. 2017; 13(4): 947-943.


Benefits of Hesperidin for Cutaneous Functions
Evidence-Based Complementary and Alternative Medicine
Mao-Qiang Man
https://doi.org/10.1155/2019/2676307