Year 2018, Volume 1, Issue 1, Pages 8 - 12 2018-07-28

THE EFFECTS OF THE SIDERITIS OZTURKII EXTRACT ON THE EXPRESSION LEVELS OF SOME APOPTOTIC GENES

Ela Nur ŞİMŞEK SEZER [1] , TUNA UYSAL [2]

66 202

Sideritis öztürkii (Lamiaceae) Aytac & Aksoy is an endemic species to Turkey and used as herbal tea and folk medicine in Central Anatolia.  The purpose of this study is to reveal the apoptotic effects of different extracts derived from S. öztürkii on DLD-1 colorectal cancer cell line via Real Time PCR technique. By this aim, the expression levels of apoptotic genes for each extract were determined via Real Time PCR and then the expression levels were evaluated and compared respectively. Especially, leaf methanol extract was found to be more effective than leaf aqueous extract in terms of apoptosis induction. The results infer that the ironwort extracts have different effects on pro and anti-apoptotic gene expression levels. In conclusion, the leaf and flower extracts have apoptosis inducing activity in the different levels on DLD-1 cell line. 

DLD-1, endemic, Turkey
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Primary Language en
Subjects Science
Journal Section First Issue
Authors

Author: Ela Nur ŞİMŞEK SEZER (Primary Author)
Institution: SELÇUK ÜNİVERSİTESİ
Country: Turkey


Author: TUNA UYSAL
Institution: SELÇUK ÜNİVERSİTESİ
Country: Turkey


Bibtex @research article { cupmap427100, journal = {Current Perspectives on Medicinal and Aromatic Plants (CUPMAP)}, issn = {2619-9645}, eissn = {2667-5722}, address = {Nazım ŞEKEROĞLU}, year = {2018}, volume = {1}, pages = {8 - 12}, doi = {}, title = {THE EFFECTS OF THE SIDERITIS OZTURKII EXTRACT ON THE EXPRESSION LEVELS OF SOME APOPTOTIC GENES}, key = {cite}, author = {ŞİMŞEK SEZER, Ela Nur and UYSAL, TUNA} }
APA ŞİMŞEK SEZER, E , UYSAL, T . (2018). THE EFFECTS OF THE SIDERITIS OZTURKII EXTRACT ON THE EXPRESSION LEVELS OF SOME APOPTOTIC GENES. Current Perspectives on Medicinal and Aromatic Plants (CUPMAP), 1 (1), 8-12. Retrieved from http://dergipark.org.tr/cupmap/issue/38636/427100
MLA ŞİMŞEK SEZER, E , UYSAL, T . "THE EFFECTS OF THE SIDERITIS OZTURKII EXTRACT ON THE EXPRESSION LEVELS OF SOME APOPTOTIC GENES". Current Perspectives on Medicinal and Aromatic Plants (CUPMAP) 1 (2018): 8-12 <http://dergipark.org.tr/cupmap/issue/38636/427100>
Chicago ŞİMŞEK SEZER, E , UYSAL, T . "THE EFFECTS OF THE SIDERITIS OZTURKII EXTRACT ON THE EXPRESSION LEVELS OF SOME APOPTOTIC GENES". Current Perspectives on Medicinal and Aromatic Plants (CUPMAP) 1 (2018): 8-12
RIS TY - JOUR T1 - THE EFFECTS OF THE SIDERITIS OZTURKII EXTRACT ON THE EXPRESSION LEVELS OF SOME APOPTOTIC GENES AU - Ela Nur ŞİMŞEK SEZER , TUNA UYSAL Y1 - 2018 PY - 2018 N1 - DO - T2 - Current Perspectives on Medicinal and Aromatic Plants (CUPMAP) JF - Journal JO - JOR SP - 8 EP - 12 VL - 1 IS - 1 SN - 2619-9645-2667-5722 M3 - UR - Y2 - 2018 ER -
EndNote %0 Current Perspectives on Medicinal and Aromatic Plants (CUPMAP) THE EFFECTS OF THE SIDERITIS OZTURKII EXTRACT ON THE EXPRESSION LEVELS OF SOME APOPTOTIC GENES %A Ela Nur ŞİMŞEK SEZER , TUNA UYSAL %T THE EFFECTS OF THE SIDERITIS OZTURKII EXTRACT ON THE EXPRESSION LEVELS OF SOME APOPTOTIC GENES %D 2018 %J Current Perspectives on Medicinal and Aromatic Plants (CUPMAP) %P 2619-9645-2667-5722 %V 1 %N 1 %R %U
ISNAD ŞİMŞEK SEZER, Ela Nur , UYSAL, TUNA . "THE EFFECTS OF THE SIDERITIS OZTURKII EXTRACT ON THE EXPRESSION LEVELS OF SOME APOPTOTIC GENES". Current Perspectives on Medicinal and Aromatic Plants (CUPMAP) 1 / 1 (July 2018): 8-12.