Year 2014, Volume 41, Issue 2, Pages 257 - 261 2014-06-01

Total antioxidant and oxidant status in obese children without insulin resistance
İnsülin direnci olmayan obez çocuklarda total antioksidan ve oksidanların durumu

Ayşegül Doğan Demir [1] , Ufuk Erenberk [2] , İlker Tolga Özgen [3] , Emin Özkaya [4] , Aysel Vahapoğlu Türkmen [5] , Mehmet Ruşen Dündaröz [6] , Özcan Erel [7]

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Objective: Oxidative stress in obese children may lead in adulthood serious conditions such as coronary heart diseases or type 2 diabetes mellitus. In childhood oxidative stress is associated with insulin resistance or extreme obesity. In this study, we aimed to evaluate oxidative stress status in moderately obese children without insulin resistance. Methods: A total of 38 obese children (21 male, 17 female) without insulin resistance, mean aged 9.4±3.8 years) and 51 normal weight children (25 male, 26 female) as the control group, mean aged 9.3±3.9 years) were enrolled to the study. Total oxidative status (TOS), total antioxidant capacity (TAC) were measured and oxidative stress index (OSI) was calculated. Results: The results reveal that obese children had lower TAC than normal weight children (2,27±0,28 vs. 2.76±0.35 mmol Trolox Eq./L; p
Amaç: Obez çocuklardaki oksidatif stres, erişkin dönemde koroner kalp hastalıkları veya tip 2 diyabet gibi ciddi durumlara öncülük edebilir. Çocukluktaki oksidatif stres insülin direnci veya ileri derece obezite ile ilişkilidir. Biz bu çalışmada, insulin direnci olmayan orta düzeyde obez çocuklarda oksidatif stres durumunu değerlendirmeyi amaçladık. Yöntemler: İnsülin direnci olmayan 38 obez çocuk (21 erkek,17 kız, ortalama yaş 9,4±3,8 yıl) ve kontrol grubu olarak 51 normal ağırlıklı çocuk (25 erkek, 26 kız, ortalama yaş 9,3±3,9 yıl) çalışmaya alındı. Total oksidatif durum (TOD), total antioksidan kapasite (TAK) ölçüldü ve oksidatif stres indeksi (OSİ) hesaplandı. Bulgular: Sonuçlar obez çocukların normal ağırlıklı çocuklardan daha düşük TAK\'a sahip olduğunu ortaya koydu (2,27±0,28 ve 2,76±0,35 mmol Trolox Eq./L; p
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Primary Language tr
Journal Section Research Articles
Authors

Author: Ayşegül Doğan Demir

Author: Ufuk Erenberk

Author: İlker Tolga Özgen

Author: Emin Özkaya

Author: Aysel Vahapoğlu Türkmen

Author: Mehmet Ruşen Dündaröz

Author: Özcan Erel

Dates

Publication Date: June 1, 2014

Bibtex @ { dicletip63819, journal = {Dicle Tıp Dergisi}, issn = {1300-2945}, eissn = {1308-9889}, address = {Dicle University}, year = {2014}, volume = {41}, pages = {257 - 261}, doi = {10.5798/diclemedj.0921.2014.02.0412}, title = {İnsülin direnci olmayan obez çocuklarda total antioksidan ve oksidanların durumu}, key = {cite}, author = {Demir, Ayşegül Doğan and Erenberk, Ufuk and Özgen, İlker Tolga and Özkaya, Emin and Türkmen, Aysel Vahapoğlu and Dündaröz, Mehmet Ruşen and Erel, Özcan} }
APA Demir, A , Erenberk, U , Özgen, İ , Özkaya, E , Türkmen, A , Dündaröz, M , Erel, Ö . (2014). İnsülin direnci olmayan obez çocuklarda total antioksidan ve oksidanların durumu. Dicle Tıp Dergisi, 41 (2), 257-261. DOI: 10.5798/diclemedj.0921.2014.02.0412
MLA Demir, A , Erenberk, U , Özgen, İ , Özkaya, E , Türkmen, A , Dündaröz, M , Erel, Ö . "İnsülin direnci olmayan obez çocuklarda total antioksidan ve oksidanların durumu". Dicle Tıp Dergisi 41 (2014): 257-261 <http://dergipark.org.tr/dicletip/issue/4686/63819>
Chicago Demir, A , Erenberk, U , Özgen, İ , Özkaya, E , Türkmen, A , Dündaröz, M , Erel, Ö . "İnsülin direnci olmayan obez çocuklarda total antioksidan ve oksidanların durumu". Dicle Tıp Dergisi 41 (2014): 257-261
RIS TY - JOUR T1 - İnsülin direnci olmayan obez çocuklarda total antioksidan ve oksidanların durumu AU - Ayşegül Doğan Demir , Ufuk Erenberk , İlker Tolga Özgen , Emin Özkaya , Aysel Vahapoğlu Türkmen , Mehmet Ruşen Dündaröz , Özcan Erel Y1 - 2014 PY - 2014 N1 - doi: 10.5798/diclemedj.0921.2014.02.0412 DO - 10.5798/diclemedj.0921.2014.02.0412 T2 - Dicle Tıp Dergisi JF - Journal JO - JOR SP - 257 EP - 261 VL - 41 IS - 2 SN - 1300-2945-1308-9889 M3 - doi: 10.5798/diclemedj.0921.2014.02.0412 UR - https://doi.org/10.5798/diclemedj.0921.2014.02.0412 Y2 - 2019 ER -
EndNote %0 Dicle Medical Journal İnsülin direnci olmayan obez çocuklarda total antioksidan ve oksidanların durumu %A Ayşegül Doğan Demir , Ufuk Erenberk , İlker Tolga Özgen , Emin Özkaya , Aysel Vahapoğlu Türkmen , Mehmet Ruşen Dündaröz , Özcan Erel %T İnsülin direnci olmayan obez çocuklarda total antioksidan ve oksidanların durumu %D 2014 %J Dicle Tıp Dergisi %P 1300-2945-1308-9889 %V 41 %N 2 %R doi: 10.5798/diclemedj.0921.2014.02.0412 %U 10.5798/diclemedj.0921.2014.02.0412
ISNAD Demir, Ayşegül Doğan , Erenberk, Ufuk , Özgen, İlker Tolga , Özkaya, Emin , Türkmen, Aysel Vahapoğlu , Dündaröz, Mehmet Ruşen , Erel, Özcan . "İnsülin direnci olmayan obez çocuklarda total antioksidan ve oksidanların durumu". Dicle Tıp Dergisi 41 / 2 (June 2014): 257-261. https://doi.org/10.5798/diclemedj.0921.2014.02.0412
AMA Demir A , Erenberk U , Özgen İ , Özkaya E , Türkmen A , Dündaröz M , Erel Ö . İnsülin direnci olmayan obez çocuklarda total antioksidan ve oksidanların durumu. Dicle Tıp Dergisi. 2014; 41(2): 257-261.
Vancouver Demir A , Erenberk U , Özgen İ , Özkaya E , Türkmen A , Dündaröz M , Erel Ö . İnsülin direnci olmayan obez çocuklarda total antioksidan ve oksidanların durumu. Dicle Tıp Dergisi. 2014; 41(2): 261-257.