TY - JOUR T1 - Development and validation of an HPLC method for determination of quercetin AU - Demirtürk, Esra AU - Onan, Deniz AU - Çevikelli, Tilbe AU - Güven, Umay Merve PY - 2022 DA - December Y2 - 2022 DO - 10.37662/jpt.2022.1000275 JF - Journal of Pharmaceutical Technology JO - J Pharm Technol PB - Mustafa Sinan KAYNAK WT - DergiPark SN - 2717-7904 SP - 1 EP - 6 VL - 3 IS - 1 LA - en AB - AbstractThis study validated a high performance liquid chromatography (HPLC) method for the determination of quercetin (QE) in microemulsion (ME) based gel formulations. The analyses were performed on a C18 column (150x4.6 mm, 5 m particle size) at room temperature with UV detection at 254 nm. The mobile phase was composed of methanol:water (65:35, v/v, 2% acetic acid) mixture, and flow rate was set to 1 mL/min. The method was validated according to the international guidelines with respect to linearity range, stability, limit of quantitation and detection, precision and accuracy. 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(2003); 18, 113-120. https://doi.org/10.1016/S0928-0987(02)00251-8 UR - https://doi.org/10.37662/jpt.2022.1000275 L1 - https://dergipark.org.tr/en/download/article-file/1992712 ER -