TY  - JOUR
T1  - Erken evreli glottik kanserlerde cerrahi tedavi seçimi ve onkolojik sonuçlar
TT  - An evaluation of surgical techniques and oncologic results in early glottic cancers
AU  - Gürbüz, M. Kezban
AU  - Özüdoğru, Erkan
AU  - Çaklı, Hamdi
AU  - Cingi, Emre
AU  - Keçik, Cem
AU  - Cingi, Cemal
PY  - 2003
DA  - October
JF  - The Turkish Journal of Ear Nose and Throat
JO  - Tr-ENT
PB  - Istanbul University
WT  - DergiPark
SN  - 2602-4837
SP  - 194
EP  - 198
VL  - 10
IS  - 5
LA  - tr
AB  - A m a ç : Erken evreli glottik kanser tanısı ile cerrahi teda- vi uygulanan olgularda seçilen cerrahi yöntem ve sağka- lım oranları değerlendirildi. Hastalar ve Yöntemler: Çalıflmaya erken evreli glottik kanseri nedeniyle cerrahi tedavi gören 29 hasta  alındı. Ön komis- sür tutulumu, sub- veya supraglottik yayılım derecesi ve kord mobilitesi gibi faktörler göz önüne alınarak uygula- nan cerrahi yöntemler ve sağkalım oranları belirlendi. Tü- mörlerin TNM sınıflandırması American Joint Committee on Cancer  AJCC  1992 ölçütlerine göre yapıldı.  Bulgular: Tümör evreleri iki olguda  %7  TisN0, 20 ol- guda  %69  T1N0, yedi olguda  %24  T2N0bulundu. Dokuz olguda  %31  larengofissür+kordektomi, 18 ol- guda  %62  frontolateral larenjektomi, iki olguda  %7  vertikal hemilarenjektomi yapıldı. On olgunun ameliyat sonrası histopatolojik incelemelerinde cerrahi sınır po- zitifliği belirlendi. Bunların dördü radyoterapi sonrasın- da, diğer dördü rutin kontrollerinde sorunsuz olarak iz- lendi; diğer iki olguda ise nüks nedeniyle total larenjek- tomi yapıldı. Yalnızca üç olgu hastalık dıflı nedenlerle kaybedildi. İki yıllık sağkalım oranı %88.8, befl yıllık sağkalım oranı %80 bulundu. Sonuç: Erken evreli glottik kanserli hastalarda, ön komissür tutulumu, subglottise, supraglottise ve ventri- küle yayılım derecesi uygulanacak cerrahi yöntemin seçiminde büyük önem taflımaktadır
KW  - Karsinom
KW  - yassı epitel hücreli/sınıflandırma
KW  - glottis/cerrahi
KW  - larenjeal neoplazmlar/sınıflandırma/cerrahi
KW  - larenjektomi/yöntem
KW  - neoplazm nüksü
KW  - lokal
KW  - neoplazm evrelemesi
KW  - sağkalım oranı
N2  - Objectives: We evaluated the surgical techniques employed and survival rates in patients who were treat- ed for early glottic cancer.Patients and Methods: The study included 29 patients  28 males, 1 female; mean age 59 years; range 47 to 73 years  who unden/vent surgery for early glottic cancer. Surgical techniques were employed in view of factors such as involvement of the anterior commissure, the extent of sub- or supraglottic invasion, and cord mobility. Two- and five- year survival rates were calculated. TNM classification was made according to the 1992 AJCC staging system.Ffesults: Preoperative tumor stages were TjsN0  n=2, 7% , T ^ g  n=20, 69% , and T2N0  n=7, 24% . Surgical tech- niques included laryngofissure and cordectomy  n=9,31% , frontolateral laryngectomy  n=18, 62% , and vertical hemi- laryngectomy  n=2, 7% . Positive surgical margins were reported postoperatively in 10 patients, eight of whom remained tumor-free with  n=4  or vvithout  n=4  radiation therapy during the follow-up period, while two patients unden/vent total laryngectomy because of local recurrences.Three patients died due to causes other than the primary disease. Two- and five-year survival rates were 88.8% and 80%, respectively.Conclusion: İnvolvement of the anterior commissure, and the extent of invasion to the subglottis, supraglottis, and the laryngeal ventricle seem to play a majör role in selecting the most appropriate surgical technique in early glottic cancer
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UR  - https://dergipark.org.tr/en/pub/trent/issue//1045707
L1  - https://dergipark.org.tr/en/download/article-file/2155427
ER  -