@article{article_1045868, title={Karyometric analysis of nasal polyps}, journal={The Turkish Journal of Ear Nose and Throat}, volume={16}, pages={251–254}, year={2006}, author={Yıldırım, Altan and Özdemir, Öztürk and Gül, Eylem and Yıldırım, Beyazıt and Elagöz, Şahende and Kunt, Tanfer}, keywords={Karyometry, nasal polyp}, abstract={Objectives: Nuclear characteristics of epithelial cells in nasal polyps were analyzed.Patients and Methods: The slides of 35 patients who undervvent surgery for nasal polyposis and 18 slides of normal mucosa were examined. The specimens were stained with hematoxylineosin. Tissue sections were analyzed by a CCD camera and the Karyotype Program of Human Cytogenetics Nomenclature System on a Macintosh Computer OS 9 . Fifty epithe­lial cells in each slide were randomly selected and transferred to the automated karyotyping system and photographed. The diameters of the nuclei were mea- sured and some peculiar nuclear features were exam- ined, including unsmooth appearance of the nuclear membrane, anaphase-bridge, and binucleation.Results: There were significant differences between nasal polyp and normal mucosa groups in terms of nuclear diameter, perimeter, and volüme, with ali variables being greater in the nasal polyp group p=0.001 . Unusual nuclear features differed significantly unsmooth nuclear membrane appearance, p <0.001; anaphase-bridge, p=0.041; binucleation, p=0.018 , as well.Conclusion: Epithelial cells of nasal polyps exhibit nuclear instability.}, number={6}, publisher={Istanbul University}