@article{article_1047838, title={THE ETIOLOGICAL FACTORS OF THE LOWER EXTREMITY VENOUS INSUFFICIENCY IN PREGNANCY}, journal={Karya Journal of Health Science}, volume={3}, pages={150–153}, year={2022}, DOI={10.52831/kjhs.1047838}, author={İştar, Hande and Kasap, Burcu and Çullu, Neşat and Depboylu, Burak Can and Yazman, Serkan and İlhan, Gökhan and Arslan, Kadir and Tetik Saruhan, Mürüvvet Funda and Harmandar, Buğra}, keywords={Venous Insufficiency, Pregnancy, Thyroid Hormone}, abstract={Objective: Number of pregnancy has a positive correlation with the development of lower limb venous insufficiency. We purpose to reveal the relation between the venous insufficiency in pregnancy and concomittant gestational features. Method: A retrospective analysis was performed using data collected from the database of our institution between January 2016-January 2021. 35 patients were included. The informations about age, in vitro fertilisation usage, polycystic ovary syndrome (PCOS), free T4 (fT4) and TSH levels, gestational diabetes mellitus (DM), other features and reports of Doppler ultrasound (USG) were investigated. Quantitative variables were analysed using Kolmogorov-Smirnov test. The relation between qualitative variables were analysed using x2 test. Descriptive statistics of qualitative variables were considered as mean±standard deviation, median (25-75 percentile), minimum-maximum. Descriptive statistics of quantitative variables were considered as frequency (%). P <0.05 was considered as statistically significant. Results: At the time of complain about leg pain and edema in lower extremities, 60% of patients were primigravid, mean age was 28.91±6.94. Mean value of the week of pregnancy was 28.71±7.92 (12-38). Mean value of TSH and fT4 were 1.74±0.86 mIU (0.23–4.07) and 13.78±3.15 pmol/mL (5.06-7.61) respectively. Twelve patients (34.3%) had venous insufficiency in Doppler USG, 3 (25%) of them were in 2nd trimester, 9(75%) were in 3rd trimester. 41.6% had normal delivery and 58.3% had cesarian section previously. fT4/ TSH ratio was 9.98 in Doppler USG positive group and in 3rd trimester had TSH and fT4 level as 1.55±0.44 and 14.62±2.14 respectively. Conclusion: There wasn’t a close relation between symptoms and venous insufficiency in Doppler USG neither between venous insufficiency and number of pregnancy or previous method of delivery. Even though venous insufficiency increases in the 3rd trimester, venous insufficiency didn’t correlate with TSH and fT4 levels. The ratio of fT4/TSH was sligtly higher in patients with venous insufficiency.}, number={2}, publisher={Kılıçhan BAYAR}