TY - JOUR T1 - Comparison of liver biomarkers with N/L ratio, CRP, d-dimer in Covid 19 pneumonia and its effect on mortality AU - Ercan Haydar, F.gullu AU - Otal, Yavuz AU - Avcıoğlu, Gamze PY - 2022 DA - August Y2 - 2022 JF - Deneysel ve Klinik Tıp Dergisi JO - J. Exp. Clin. Med. PB - Ondokuz Mayıs University WT - DergiPark SN - 1309-4483 SP - 693 EP - 698 VL - 39 IS - 3 LA - en AB - Abstract:Background: Coronavirus Disease-2019 (Covid-19) is the cause of a pandemic that has high mortality and global effects. The liver damage in Covid-19 cases in mechanical ventilation was investigated in this study.Materials and Methods: A total of 60 patients (the Study Group) who were diagnosed with Covid-19 pneumonia, and 65 individuals (the Control Group) were included prospectively in the study. The cases were divided into 3 groups as those who were intubated (severe), those who were not intubated (mild), and the healthy Control Group. The lung tomography results of those who were diagnosed with Covid-19 were examined in the study. The cases with positive RT-PCR (Real Time Polymerized Chain Reaction) test results were recorded from the system. The liver tests of the patients were compared with those of the Control Group. The two groups with and without intubation were also compared. The results were evaluated and analyzed statistically.Results: When all the data were evaluated, it was found that LDH, GGT, AST, and aPTT levels were significantly higher in the mild and severe patient group compared to the Control Group, and the T. Protein and albumin levels were low (p KW - Covid-19 KW - Liver Function KW - mortality KW - Invasive Mechanical Ventilation KW - d-dimer CR - Referans1 Hundt MA, Deng Y, Ciarleglio MM, Nathanson MH, Lim JK. Abnormal Liver Tests in COVID-19: A Retrospective Observational Cohort Study of 1,827 Patients in a Major U.S. Hospital Network. Hepatology, 2020. 72(4): p. 1169-1176. UR - https://dergipark.org.tr/en/pub/omujecm/issue//1059345 L1 - https://dergipark.org.tr/en/download/article-file/2198136 ER -