@article{article_1063607, title={Could Hemogram Parameters Predict Extensive Pulmonary Involvement in SARS CoV-2 Infection?}, journal={Value in Health Sciences}, volume={12}, pages={453–459}, year={2022}, DOI={10.33631/sabd.1063607}, author={Coşgun, Zeliha and Kalfaoğlu, Melike Elif and Dağıstan, Emine and Özsarı, Emine and Aktas, Gulali}, keywords={Mean platelet volume, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, pulmonary involvement, SARS Cov-2}, abstract={Aim: Since the start of the pandemic, the novel coronavirus infection SARS CoV-2 has caused huge morbidity and mortality, as well as a significant economic cost. We aimed to compare clinical and laboratory findings of the SARS CoV-2 patients with mild pulmonary involvement to those in subjects with advanced pulmonary involvement. Material and Methods: In this study, the relationship between hemogram indices and pulmonary involvement in patients hospitalized for SARS CoV-2 infection at Bolu Abant Izzet Baysal University Hospital was investigated. We analyzed the thorax CT images of the subjects with SARS CoV-2 in present retrospective study. Radiological pattern of disease-related in the lungs, percentage of lung involvement, hemogram parameters, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), aspartate and alanine transaminases (AST and ALT), lactate dehydrogenase (LDH), D-dimer, ferritin, total bilirubin, albumin, creatinine kinase, serum creatinine in patients with advanced and mild pulmonary involvement were compared. Results: Advanced pulmonary involvement (greater than 50%) was positively and significantly correlated with ESR, (r=0.32, p <0.001), CRP (r=0.37, p <0.001), LDH (r=0.46, p <0.001), D-dimer (r=0.19, p <0.001), ferritin (r=0.37, p <0.001), mean platelet volume (MPV) (r=0.13, p <0.001), the neutrophil to lymphocyte ratio (NLR) (r=0.33, p <0.001) and platelet to lymphocyte ratio (PLR) (r=0.27, p <0.001). Conclusion: We suggest that MPV, PLR and NLR could be early predictors of advanced pulmonary involvement in SARS CoV-2 patients. Physicians should aware of this complication in the setting of elevated MPV, PLR or NLR levels.}, number={3}, publisher={Duzce University}, organization={No}