TY  - JOUR
T1  - Monitoring of oxidative stress and TNF-α status during the healing process in hair goats with metritis
AU  - Eşki, Funda
AU  - Kurt, Serdal
AU  - Mis, Leyla
PY  - 2022
DA  - March
DO  - 10.47748/tjvr.1069768
JF  - Turkish Journal of Veterinary Research
JO  - TJVR
PB  - Ebubekir CEYLAN
WT  - DergiPark
SN  - 2602-3695
SP  - 15
EP  - 18
VL  - 6
IS  - 1
LA  - en
AB  - Objective: This study aimed to monitor oxidative stress parameters including total antioxidant status (TAS) and total oxidant status (TOS), and tumor necrosis factor-alpha (TNF-α) level during the healing process in hair goats with metritis. Materials and Methods: This study was carried out on a total of 25 hair goats with metritis (n=10; Group 1) and healthy (n=15; Group 2). The beginning of the study was accepted as day 0. In both Group 1 and Group 2, blood samples were collected on days 0 (first measurement day), 14 (second measurement day) and 28 (third measurement day) of the study for TAS, TOS and TNF-α analyzes. In addition, oksidatif stress index (OSI) was calculated using TAS and TOS values.Results: It was found that TAS level decreased in Group 1 compared to Group 2 at the first measurement day (p
KW  - Hair goat
KW  - metritis
KW  - oksidative stress
KW  - TNF-α.
CR  - Cecchini S, Piccione G, Saoca C, Giangrosso G, Caputo AR, Fazio F. Redox status, lipid peroxidation and protein oxidation levels in small ruminants. J Anim Feed Sci. 2018; 27(1): 81-85.
CR  - Celi P. The role of oxidative stress in small ruminants' health and production. Rev Bras de Zootec. 2010; 39: 348-363.
CR  - Doumtsop CLM, Kouamo J, Njintang NY, Tangwa BV, Amatama LMM, Zangue CT. Prevalence, Etiology and Risk Factors Associated With Chronic Metritis in Small Ruminants in Adamawa Region (Cameroon). J Infertil Reprod Biol. 2021; 9(4): 147-154.
CR  - Huang Y, Wen J, Kong Y, et al. Oxidative status in dairy goats: periparturient variation and changes in subclinical hyperketonemia and hypocalcemia. BMC Vet Res. 2021; 17: 238.
CR  - Kulsum U, Juli MSB, Zohara BF, Islam MN, Akther M. Incidence of reproductive disorders of goat in Dinajpur district of Bangladesh. Asian J Med Biol Res. 2020; 6(2): 212-221.
CR  - Kurt S, Salar S, Salar MÖ. Antibiogram and pathogen isolation from vaginal discharge in dairy cows with metritis. Vet Hekim Der Derg. 2019; 90(2): 66-70.
CR  - Kurt S, Eşki F, Mis L, Demir PA. Evaluation of Oxidative Stress, Immune System and Mineral Concentrations in Milk and Serum of Cows with Clinical and Subclinical Mastitis Naturally Infected by Staphylococcus aureus. Kafkas Univ Vet Fak Derg. 2021; 27 (6): 755-762.
CR  - Kushibiki S. Tumor necrosis factor‐α‐induced inflammatory responses in cattle. Anim Sci J. 2011; 82(4): 504-511.
CR  - Lykkesfeldt J, Svendsen O. Oxidants and antioxidants in disease: oxidative stress in farm animals. Vet J. 2007; 173(3): 502-511.
CR  - Majeed AF. Obstetrical problems and their management in Iraqi goats. Small Rumin Res. 1994; 14(1): 73-78.
CR  - Mikulková K, Kadek R, Filípe J, Illek J. Evaluation of oxidant/antioxidant status, metabolic profile and milk production in cows with metritis. Ir Vet J. 2020; 73: 1-11.
CR  - Sayeed MA, Khatun MS, Bari MS, Dash AK, Haldar PK, Sarker BK. Prevalence of gynecological disorders of goat and pattern of drug used at Chuadanga, Bangladesh. Agric Sci Digest. 2020; 40(4): 424-429.
CR  - Sheldon IM, Lewis GS, LeBlanc S, Gilbert RO. Defining postpartum uterine disease in cattle. Theriogenology, 2006; 65(8): 1516-1530.
CR  - Sordillo LM, Aitken SL. Impact of oxidative stress on the health and immune function of dairy cattle. Vet Immunol Immunopathol. 2009; 128(1-3): 104-109.
CR  - Skarzynski DJ, Piotrowska KK, Bah MM, Korzekwa A, Woclawek‐Potocka I, Sawai K, et al. Effects of Exogenous Tumour Necrosis Factor‐α on the Secretory Function of the Bovine Reproductive Tract Depend on Tumour Necrosis Factor‐α Concentrations. Reprod Domest Anim. 2009; 44(3): 371-379.
CR  - Williams EJ, Sibley K, Miller AN, et al. The effect of Escherichia coli lipopolysaccharide and tumour necrosis factor alpha on ovarian function. Am J Reprod Immunol. 2008; 60(5): 462-473.
UR  - https://doi.org/10.47748/tjvr.1069768
L1  - https://dergipark.org.tr/en/download/article-file/2239034
ER  -