@article{article_1084080, title={The Clinical Correlations of Fatigue in Patients with Sarcoidosis}, journal={Konuralp Medical Journal}, volume={14}, pages={497–502}, year={2022}, DOI={10.18521/ktd.1084080}, author={Yıldız Gülhan, Pınar and Güleç Balbay, Ege and Erçelik, Merve and Annakkaya, Ali and Arbak, Peri and Özdemir Kumbasar, Özlem}, keywords={Fatigue Assessment Scale (FAS), fatique, health quality, sarcoidosis}, abstract={Objective: Fatigue is considered a frequent and characteristic feature of sarcoidosis. This study was designed to determine the prevalence of fatigue in patients with sarcoidosis and to determine its potential clinical correlations in relation to symptom severity. Methods: A total of 56 sarcoidosis patients were included. Data on patient demographics, anthropometrics, disease characteristics, pulmonary function tests, 6-min walking distance (6MWD), blood biochemistry and hemogram findings were retrieved from hospital records. Psychometric instruments involved the fatigue assessment scale (FAS), Beck Depression Inventory (BDI) and Short Form-36 (SF-36) for health-related QOL (HRQOL). Results: Mean±SD patient age was 50.9±11.9 years. Of 56 patients, 44 were females and 12 were males. When compared to FAS score <22 and FAS score ≥22-34 subgroups, FAS score ≥35 (severe fatigue) subgroup was associated with significantly higher patient age and significantly lower SF-36 physical health scores. Total FAS scores were correlated positively with age (r=0.349, p=0.008) and BDI scores (r=0.515, p <0.001), while negatively with MIP (r=-0.321, p=0.019) and SF-36 physical health (r=-0.402, p=0.003) and mental health (r=-0.351, p=0.009) scores. BDI score (OR 1.146, 95% CI: 1.020 to 1.288, p=0.021) was determined to be the single independent predictor of the increased likelihood of a patient with sarcoidosis having FAS score ≥22. Conclusions: Our findings emphasize that deterioration in respiratory functions may contribute to the development of fatigue among sarcoidosis patients, and besides the fatigue, depressive symptoms and anxiety should also be an integral part of the multidisciplinary management of sarcoidosis patients.}, number={3}, publisher={Duzce University}