TY  - JOUR
T1  - Isolated neuro-Behçet’s disease in a child, from headache to diagnosis: A case report
TT  - Isolated neuro-Behçet’s disease in a child, from headache to diagnosis: A case report
AU  - İpek, Rojan
AU  - Ten, Barıs
AU  - Kömür, Mustafa
AU  - Okuyaz, Cetin
PY  - 2022
DA  - June
DO  - 10.5798/dicletip.1129520
JF  - Dicle Medical Journal
JO  - diclemedj
PB  - Dicle University
WT  - DergiPark
SN  - 1300-2945
SP  - 381
EP  - 384
VL  - 49
IS  - 2
LA  - en
AB  - Behçet's disease (BD) is an immuno-inflammatory multi-systemic disease characterized by ophthalmological and skin involvement, also oral and genital ulcers. Its etiology and pathogenesis are not clearly known. Neuro-Behçet's disease can occur as an isolated form or a rare complication of BD. Besides, diagnosis of neuro-Behçet's disease is difficult. Since Neuro-Behçet can result in morbidity and mortality, early diagnosis and treatment are important. The most important genetic factor in the pathogenesis of BD is Human Leucocyte Antigen (HLA-B 51) allele positivity. A 9-year-old girl was brought to our outpatient clinic for 6 months with a migraine-like headache. The headache of the patient has a partial response to analgesics and rarely awakes from sleep at night accompanied by vomiting. The patient was diagnosed with an isolated neuro-Behçet's disease by HLA-B 51 allele positivity and brain magnetic resonance imaging (MRI) findings. In the current study, the roles of HLA-B 51 allele positivity and brain MRI findings were discussed in the diagnosis of neuro-Behçet's disease.
KW  - HLA-B51 positivity
KW  - Isolated neuro-Behçet
KW  - Migrain like headache; MRI.
CR  - 1.Behçet H. Uber residivierende, aphtosedurcheinVirus verursachte Geschwure am Mund, am Augeund an den Genitalien. DermWschr. 1937; 105:1152-57.
CR  - 2. Saip S, Akman DG, Siva A. Neuro-Behçet syndrome. HandbClin Neurol. 2014; 121: 1703-23.
CR  - 3.Knapp P. Beitragzur symptomatologie undtherapie der rezidivieren den hypopyoniritis undder begleiten denaphtozenschleimhauterkrankungen. Schweiz MedWochenschr. 1941; 71: 1288-90.
CR  - 4.Davatchi F. Diagnosis/classification criteria forBehçet’s disease. Patholog Res Int. 2012; 2012:607921.
UR  - https://doi.org/10.5798/dicletip.1129520
L1  - https://dergipark.org.tr/en/download/article-file/2481315
ER  -