@article{article_1193464, title={Norepinephrine infusion in brain dead organ donor: A retrospective study on its effects on graft function after renal transplant}, journal={Yeni Üroloji Dergisi}, volume={18}, pages={135–144}, year={2023}, DOI={10.33719/yud.2023;18-2-1193464}, author={Korkmaz, Hamide Ayben and Apaydın, Yilmaz and Ceylan, İlkay}, keywords={brain dead, organ donors, vasoactive drugs, graft survival}, abstract={Objective: To investigate the effect of vasoactive drugs use in brain-dead organ donors in renal recipient graft function.
Material and Methods: Clinical data from 30 brain-dead organ donors, and 30 recipients in our center were
analyzed retrospectively between July 2017 and November 2021.
Results: Norepinephrine infusion was used in all 30 cadaveric donors, where 11 donors had inotropic combinations. Norepinephrine was infused at a median dose of 0.2mcg/kg/min. There was no relationship between duration and doses of norepinephrine in donors and graft rejection, graft loss, and dialysis requirement in renal recipients.
Conclusion: Intravenous norepinephrine infusion below 0.2mcg/kg/min had no effect on graft
function in the renal recipient, where fluid restitution was sufficient in the cadaveric donor.}, number={2}, publisher={Ali İhsan TAŞÇI}