TY - JOUR T1 - SCUBE-1 as a novel predictor of thromboembolic event AU - Akça, Hatice Şeyma PY - 2023 DA - March Y2 - 2023 JF - Deneysel ve Klinik Tıp Dergisi JO - J. Exp. Clin. Med. PB - Ondokuz Mayıs University WT - DergiPark SN - 1309-4483 SP - 197 EP - 198 VL - 40 IS - 1 LA - en AB - SCUBE-1 is a newly identified, secreted cell surface protein that is determined during early embryogenesis. This protein consists of cascading EGF-like repeats following the N-terminal signal peptide sequence, a spacer region, cysteine-rich repeat motifs, and a CUB domain at the C-terminus. These molecules are stored in alpha granules in inactivated platelets, translocated to the platelet surface after activation by thrombin, secreted as small soluble fragments, and incorporated into the thrombus. KW - SCUBE-1 KW - thromboembolic events KW - myocardial infarction UR - https://dergipark.org.tr/en/pub/omujecm/issue//1216065 L1 - https://dergipark.org.tr/en/download/article-file/2818953 ER -