TY - JOUR T1 - Evaluation of Acute Drug Intoxications and Drug Use in the Intensive Care Unit: A Retrospective, Single-Center Analysis TT - Yoğun Bakım Ünitesinde Takip Edilen Akut İlaç İntoksikasyonları ve Uyuşturucu Madde Kullanımlarının Değerlendirilmesi: Retrospektif, Tek Merkez Analizi AU - Arslan, Kadir AU - Şahin, Ayça Sultan PY - 2023 DA - April Y2 - 2023 DO - 10.36516/jocass.1216712 JF - Journal of Cukurova Anesthesia and Surgical Sciences JO - J Cukurova Anesth Surg PB - Merthan TUNAY WT - DergiPark SN - 2667-498X SP - 75 EP - 83 VL - 6 IS - 1 LA - en AB - Aim: Drug intoxications and drug uses are public health problems and an important reason for patient admission to emergency departments and intensive care units (ICU).This study aims to evaluate the demographic and clinical data of acute drug intoxications and drug use.Methods: Patients followed up in the ICU for acute drug intoxications and drug use between January 2014 and January 2020 were evaluated retrospectively.Results: A total of 194 patients were included in the study, including 168 drug intoxication and 26 drug use. While 59.5% of drug intoxications were female, the mean age was 27.8±8.3 years, 92.3% of drug use was male, and the mean age was 26.5±3.8 years. While the mean duration of stay in the ICU was 2.3±1.2 days for drug intoxications, it was 2.8±1.9 days for drug use. The highest rate of drug intoxication was between the ages of 17-30, and 98.8% of them were suicidal. Most of the intoxications (61.9%) occurred with multiple drugs, most commonly with analgesics (40.4%) and antidepressants (34.5%). The mortality rate of drug intoxication was 0.6%, and the mortality rate of drug users was 11.5%. While male gender and mechanical ventilation (Mv) requirement were significantly higher in drug use, Glasgow coma scale (GCS) scores at discharge and hospitalization were significantly lower (p KW - Drug use KW - intensive care unit KW - intoxication KW - suicide N2 - Amaç: İlaç intoksikasyonları ve uyuşturucu madde kullanımları, acil servisler ve Yoğun bakım ünitelerine (YBÜ) hasta kabulünün önemli bir sebebi olmakla birlikte bir halk sağlığı problemidir. Bu çalışmanın amacı, akut ilaç intoksikasyonları ve uyuşturucu madde kullanımlarının demografik ve klinik verilerinin değerlendirilmesidir.Yöntemler: Ocak 2014 ile Ocak 2020 tarihleri arasında YBÜ’de akut ilaç intoksikasyonları ve uyuşturucu kullanımı nedeniyle takip edilen hastalar retrospektif olarak değerlendirildi. Bulgular: 168 ilaç intoksikasyonu ve 26 uyuşturucu madde kullanımı olmak üzere 192 hasta çalışmaya dahil edildi. İlaç intoksikasyonlarının %59.5’i kadın ve yaş ortalaması 27.8±8.3 yıl iken uyuşturucu madde kullanımlarının %92.3’ü erkek ve yaş ortalaması 26.5±3.8 yıl idi. Ortalama YBÜ’de kalma süresi ilaç intoksikasyonlarında 2.3±1.2 gün iken, uyuşturucu madde kullanımlarında 2.8±1.9 gün idi. İlaç intoksikasyonları en fazla oranda 17-30 yaş aralığındaydı ve %98.8’i intihar amaçlıydı. İntoksikasyonların büyük kısmı (%61.9) çoklu ilaçlarla en sık da analjezik (%40.4) ve antidepresanlarla (%34.5) meydana geldi. İlaç intoksikasyonlarının mortalite oranı %0.6 ve uyuşturucu madde kullananların mortalitesi %11.5 idi. Uyuşturucu madde kullanımlarında erkek cinsiyet ve Mv gereksinimi anlamlı olarak yüksek iken, taburculuk ve yatış sırasındaki Glaskow koma skalası (GKS) skorları anlamlı olarak düşük idi (p CR - 1) Dart RC, Bronstein AC, Spyker DA, et al. Poisoning in the United States: 2012 emergency medicine report of the National Poison Data System. 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