@article{article_1241429, title={Clinicopatological Examination of Waldeyer’s Ring Lymphomas: A Cross-Sectional Study in Turkey}, journal={Balıkesir Sağlık Bilimleri Dergisi}, volume={12}, pages={81–88}, year={2023}, DOI={10.53424/balikesirsbd.1241429}, author={Özdemir, Çiğdem and Eryeğen, Nilhan and Yavaşoğlu, Filiz and Ak, Mehmet Olgun and Kuzu, Selçuk and Duran, Mustafa and Belen Aydoğmuş, Burcu and Çetinkaya, Büşra and Bucak, Abdulkadir and Şenol, Yiğit}, keywords={Non-Hodgkin Lymphoma, Tonsil, Hodgkin Lymphoma, Nasopharynx}, abstract={Objective: Waldeyer’s ring (WR) is the second most common site of extranodal lymphomas. Its clinical course may resemble those of nodal lymphomas. We evaluated the histopathological and clinical findings, Epstein-Barr virus (EBV) presence, and overall survival of WR lymphomas diagnosed in our department. Materials and Methods: Retrospectively, 32 patients were included. The demographic and clinical data of the patients and lymphoma types, the presence of EBV [EBV early RNAs (EBER)] by chromogenic in-situ hybridization (CISH) method were examined. Kaplan-Meier analysis was used for the survival rate. A P value less than 0.05 was considered statistically significant. Results: 23 of 32 cases were male. The mean age was 57.97±16.15 years. The preliminary clinical diagnosis was carcinoma in 46.9% of the cases. Tonsil and nasopharynx had equal proportions as lymphoma origin. Only 3 (9.4%) cases are classic Hodgkin lymphoma (CHL). 16 cases (50.0%) were diffuse large B-cell lymphoma (DLBCL). EBER was detected only in tonsillar CHL cases. The survival of patients with nasopharyngeal lymphoma was shorter than those of tonsillar origin (p=0.037). Conclusion: DLBCL is the most common lymphoma type of this localization. EBER positivity has been detected only in CHL. Survival is lower in lymphomas originating from the nasopharynx}, number={1}, publisher={Balıkesir University}