TY - JOUR T1 - Bladder Crystal Formation shown as false positive cause in F-18 Fluorodeoxyglucose (FDG) Positron Emission Tomography/Computed Tomography (PET/CT) AU - Koç, Zehra Pınar PY - 2022 DA - April JF - Molecular Oncologic Imaging PB - Mersin University WT - DergiPark SN - 2791-965X SP - 9 EP - 11 VL - 2 IS - 1 LA - en AB - Introduction: There are some false positivity reasons for the bladder in FDG PET/CT. This case report demonstrates one of these causes which were not reported before. Case and outcomes: A male patient sixty-five years of age with known diagnosis of metastatic colon carcinoma receiving chemotherapy treatment referred for follow up FDG PET/CT which showed partial metabolic response and suspicious calcified lesion in the bladder wall with significant FDG accumulation. Cystoscopy and pathology results demonstrated crystal formation and adjacent inflammation as an explanation. Discussion: The FDG accumulations due to foreign materials have been reported in elsewhere in the body before in the literature. This accumulation in this case may represent foreign body reaction. Conclusion: This case report showed an interesting false positive lesion demonstrated firstly in the literature as far as we know. The follow up results confirmed that the FDG accumulation in the bladder was a false positive. KW - Crystal KW - False Positive KW - FDG PET/CT CR - 1. Boudabbous S., Arditi D., Paulin E., Koessler T., Rougemont A.L., Montet X. Ossifying metaplasia of urothelial metastases: original case with review of the literature. BMC Med Imaging. 2015 ;15:30 CR - 2. Cormio L., Sanguedolce F., Massenio P., Di Fino G., Selvaggio O., Bufo P., et al. Osseous metaplasia within a urothelial bladder cancer nodal metastasis: a case report. Anal Quant Cytopathol Histpathol. 2014;36:117–9 CR - 3. Gladdy R.A., Qin L.X., Moraco N., Edgar M.A., Antonescu C.R., Alektiar K.M., et al. Do radiation-associated soft tissue sarcomas have the same prognosis as sporadic soft tissue sarcomas? J Clin Oncol. 2010;28:2064–9 CR - 4. Mantzarides M., Papathanassiou D., Bonardel G., et al. High-grade lymphoma of the bladder visualized on PET. Clin Nucl Med. 2005; 30:478-80 CR - 5. Treglia G., Bongiovanni M., Giovanella L. A rare case of small cell neuroendocrine carcinoma of the urinary bladder incidentally detected by F-18 FDG PET/CT. Endocrine. 2014; 45:156-157 CR - 6. Lin Y., Lu Y.Y., Wang H.Y., Tsai S.C., Lin W.Y. Accidental finding of bladder cancer in 99mTc methylene diphosphonate whole-body bone scan. Clin Nucl Med. 2013;38:643-5 CR - 7. Parekh A., Hagan I., Capaldi L., Lyburn I. Incidental Papillary Bladder Carcinoma on 18F-Fluoromethylcholine PET/CT Undertaken to Evaluate Prostate Malignancy. Clin Nucl Med. 2017 .;42:721-722 CR - 8. Osman M.M., Altinyay M.E., Abdelmalik A.G., Brickman T.M., Varvares M.A., Nguyen N.C. FDG PET/CT incidental diagnosis of a synchronous bladder cancer as a fourth malignancy in a patient with head and neck cancer. Clin Nucl Med. 2011;36:496-7 CR - 9. De Jong I.J., Pruim J., Elsinga P.H., et al. Visualisation of bladder cancer using (11)C-choline PET: first clinical experience. Eur J Nucl Med Mol Imaging. 2002;29:1283–1288 CR - 10. Tahara T., Ichiya Y., Kuwabara Y., et al. High [18F]-fluorodeoxyglucose uptake in abdominal abscesses: a PET study. J Comput Assist Tomogr. 1989;13: 829–831 UR - https://dergipark.org.tr/en/pub/moi/issue//1257056 L1 - https://dergipark.org.tr/en/download/article-file/2977022 ER -