TY  - JOUR
T1  - A Case of Acute Lymphoblastic Leukemia Complicated with Sinonasal Mucormycosis Infection
AU  - Hacımustafaoğlu, Asuman Şebnem
AU  - Orhan, Bedrettin
AU  - Ersal, Tuba
AU  - Ozkocaman, Vildan
AU  - Özkalemkaş, Fahir
PY  - 2024
DA  - January
Y2  - 2023
DO  - 10.46310/tjim.1316471
JF  - Turkish Journal of Internal Medicine
JO  - Turk J Int Med
PB  - Nizameddin KOCA
WT  - DergiPark
SN  - 2687-4245
SP  - 64
EP  - 68
VL  - 6
IS  - 1
LA  - en
AB  - Acute lymphoblastic leukemia (ALL) is an aggressive hematologic malignancy of lymphoid progenitor cells. During treatment of ALL, the patients may be complicated by fatal infections such as sinonasal mucormycosis. In patients with immunocompromised conditions like haematologic malignancies, mucormycosis can be deadly. Once mucormycosis has been detected, it is critical to act quickly to begin treatment. Amphotericin B, posaconazole, or isavuconazole are the medications of choice. Effective treatment requires a long-term course of therapy. Switching to other effective medications should be considered when the preferred treatment is not working. The factors contributing to mucormycosis must also be treated, such as the underlying conditions (haematologic malignancies). Herein, we aimed to discuss a clinically stable ALL patient complicated with extensive sinonasal mucormycosis. She improved with amphotericin B (5 mg/kg/day) and oral posaconazol (300 mg/day) treatment.
KW  - acute lymphoblastic leukemia
KW  - mucormycosis
KW  - sinonasal mucormycosis
KW  - Amphoteracin B
KW  - posaconazol
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UR  - https://doi.org/10.46310/tjim.1316471
L1  - https://dergipark.org.tr/en/download/article-file/3217911
ER  -