TY  - JOUR
T1  - Dynamic thiol/disulphide homeostasis and ischemic modified albumin levels in idiopathic polyhydramnios
TT  - İdiyopatik polihidramniyoz olgularında dinamik tiyol/disülfit homeostazı ve iskemik modifiye albümin seviyeleri
AU  - Özgürlük, İzzet
AU  - Sahin, Dilek
PY  - 2023
DA  - September
Y2  - 2023
DO  - 10.16899/jcm.1346174
JF  - Journal of Contemporary Medicine
JO  - J Contemp Med
PB  - Rabia YILMAZ
WT  - DergiPark
SN  - 2667-7180
SP  - 845
EP  - 848
VL  - 13
IS  - 5
LA  - en
AB  - Objective: The aim of study was to determine whether idiopathic polyhydramnios is in relation with dynamic thiol-disulfide homeostasis and ischemia modified albumin levels or not. Materials and methods: In this prospective case- control study, a total of 126 participants were included. The patient group consisted of 56 patients who were diagnosed idiopathic polyhydramnios, and the control group consisted of 56 healthy normal pregnant. Native thiol (-SH), total thiol (-SH. -SS), dynamic disulfide (-SS), values from maternal serum were measured and compared between groups.Results: 112 patients aged between 18-35 years, consisting of 56 idiopathic polyhydramnios and 56 control groups were included in the study. Maternal serum native and total thiol values were significantly higher in study group compared to control group (382.2 ±78.5 mmol/L vs. 331.8 ±43.9 mmol/L, p
KW  - IMA
KW  - Thiol/disulphide homeostasis
KW  - polyhydramnios
N2  - Amaç: Bu çalışmanın amacı, idiyopatik polihidramniosun dinamik tiyol-disülfit homeostazı ve iskemi modifiye albümin düzeyleri ile ilişkisinin olup olmadığını belirlemektir.Gereç ve Yöntemler: Bu prospektif vaka kontrol çalışmasına toplam 126 katılımcı dahil edildi. Hasta grubunu idiyopatik polihidramnios tanısı alan 56 hasta ve kontrol grubunu 56 sağlıklı normal gebe oluşturdu. Native tiyol (-SH), total tiyol (-SH.-SS), dinamik disülfid (-SS), maternal serum değerleri ölçüldü ve gruplar arasında karşılaştırıldı.Bulgular: Çalışmaya 56 idiyopatik polihidramnios ve 56 kontrol grubu olmak üzere 18-35 yaş arası 112 hasta dahil edildi. Maternal serum nativ ve total tiyol değerleri çalışma grubunda kontrol grubuna göre anlamlı derecede yüksekti (382,2 ±78,5 mmol/L - 331,8 ±43,9 mmol/L, p
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UR  - https://doi.org/10.16899/jcm.1346174
L1  - https://dergipark.org.tr/en/download/article-file/3345943
ER  -