TY  - JOUR
T1  - Aksiyel Spondiloartritte C-Reaktif Protein/Albumin Oranının Hastalık Aktivitesi ile İlişkisi
TT  - The Relationship Between C-Reaktif Protein/Albumin Ratio and Disease Activity in Axial Spondyloarthritis
AU  - Oruçoğlu, Nurdan
AU  - Önder, Mustafa Erkut
AU  - Omar, Fırat
PY  - 2024
DA  - February
Y2  - 2023
DO  - 10.52827/hititmedj.1346698
JF  - Hitit Medical Journal
JO  - Hitit Medical Journal
PB  - Hitit University
WT  - DergiPark
SN  - 2687-4717
SP  - 33
EP  - 41
VL  - 6
IS  - 1
LA  - tr
AB  - Amaç: C-reaktif protein/albümin oranı (CAO) yakın zamanda yeni bir inflamatuar biyobelirteç olarak tanımlanmış ve inflamasyonun belirlenmesinde birçok hastalıkta potansiyel rolü ortaya konulmuştur. Bu çalışma, aksiyel spondiloartritte (axSpA) hastalık aktivitesinin belirlenmesinde CAO’nun rolünü araştırmayı amaçlamaktadır. Gereç ve Yöntem: Bu çalışma retrospektif vaka-kontrol çalışmasıdır. Toplam 128 hasta ve 111 yaş-cinsiyet uyumlu sağlıklı kontrol çalışmaya dahil edilmiştir. Serum albumin, C-reaktif protein (CRP), eritrosit sedimantasyon hızı (ESH) kaydedildi. CAO, serum CRP/Albumin şeklinde hesaplanmıştır. Hastalık aktivitesini belirlemek için Bath Ankilozan Spondilit Hastalık Aktivite İndeksi (BASDAI) ve Ankilozan Spondilit Hastalık Aktivite Skoru-CRP (ASDAS-CRP) skorları kullanıldı. Hastalar ASDAS-CRP skoruna göre iki alt gruba ayrıldı: ≥1,3 aktif hastalık,
KW  - C-reaktif protein
KW  - Aksiyal Spondiloartrit
KW  - albumin
KW  - C-reaktif protein/albumin oranı inflamasyon
N2  - Objective: The C-reactive protein/albumin ratio (CAR) has recently emerged as a novel inflammatory biomarker, indicating its potential role in determining inflammation in various disorders. This study aims to investigate the role of CAO in determining disease activity in axial spondyloarthritis (axSpA).Materials and Methods: This study is a retrospective case-control study. A total of 128 patients with axSpA and 111 age-gender-matched healthy controls were included in the study. Serum albumin, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) were recorded. CAR was calculated as serum CRP/Albumin. The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Ankylosing Spondylitis Disease Activity Score-CRP (ASDAS-CRP) scores were used to determine disease activity. Patients were divided into two subgroups based on the ASDAS-CRP score: ≥1.3 was considered active disease, and
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UR  - https://doi.org/10.52827/hititmedj.1346698
L1  - https://dergipark.org.tr/en/download/article-file/3348114
ER  -