TY - JOUR T1 - Antioxidant activity of polyphenol compounds extracted from Nypa fruticans Wurmb. (Nipa palm) fruit husk with different ethanol concentration TT - Antioxidant activity of polyphenol compounds extracted from Nypa fruticans Wurmb. (Nipa palm) fruit husk with different ethanol concentration AU - Sudirman, Sabri AU - Wardana, Aprilia Kusuma AU - Herpandı, Herpandi AU - Widiastuti, Indah AU - Sarı, Dwi Inda AU - Janna, Miftahul PY - 2024 DA - June DO - 10.21448/ijsm.1360736 JF - International Journal of Secondary Metabolite JO - Int. J. Sec. Metabolite PB - İzzet KARA WT - DergiPark SN - 2148-6905 SP - 355 EP - 363 VL - 11 IS - 2 LA - en AB - Oxidative stress is a condition characterized by a higher content of free radicals than the potential antioxidants in the body. Exogenous antioxidants are needed to resolve this condition. The Nypa fruticans (Nipa palm) fruit husk is a source of polyphenol potential and can be used as a natural antioxidant agent. Therefore, this study aimed to determine the effect of ethanol concentration on polyphenol and tannin contents and their antioxidant activities. The polyphenol substances were extracted using several ethanol concentrations, whereas the antioxidant activity was determined using the 2,2-diphenyl-1-picrylhydrazyl method. The results show that the ethanol concentration has no effect on the yield of extraction. However, it affects the total polyphenol and tannin contents with high levels in the 50% and 70% ethanol concentrations. Fifty percent ethanol exhibits more effective antioxidant activity when compared to other ethanol concentrations. Therefore, a 50% ethanol concentration is a suitable solvent to extract polyphenol and tannin substances from nipa palm fruit husk and can be used as an alternative natural antioxidant. KW - Antioxidant KW - Nipa palm KW - Nypa fruticans KW - Polyphenol KW - Tannin N2 - Oxidative stress is a condition characterized by a higher content of free radicals than the potential antioxidants in the body. Exogenous antioxidants are needed to resolve this condition. The Nypa fruticans (Nipa palm) fruit husk is a source of polyphenol potential and can be used as a natural antioxidant agent. Therefore, this study aimed to determine the effect of ethanol concentration on polyphenol and tannin contents and their antioxidant activities. The polyphenol substances were extracted using several ethanol concentrations, whereas the antioxidant activity was determined using the 2,2-diphenyl-1-picrylhydrazyl method. The results show that the ethanol concentration has no effect on the yield of extraction. However, it affects the total polyphenol and tannin contents with high levels in the 50% and 70% ethanol concentrations. 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