TY  - JOUR
T1  - Relationship between COVID-19 and antimicrobial resistance
AU  - Müderris, Tuba
AU  - Kaya, Selcuk
AU  - Bayındır Bilman, Fulya
AU  - Ozmen, Erkan
AU  - Peker, Bilal Olcay
AU  - Aksoy Gökmen, Ayşegül
AU  - Gül Yurtsever, Süreyya
PY  - 2023
DA  - September
DO  - 10.5472/marumj.1367895
JF  - Marmara Medical Journal
JO  - Marmara Med J
PB  - Marmara University
WT  - DergiPark
SN  - 1019-1941
SP  - 312
EP  - 318
VL  - 36
IS  - 3
LA  - en
AB  - Objective: Bacterial and fungal infections, antimicrobial resistance (AMR) results of bacterial agents, and the effect of the pandemicon AMR were evaluated in hospitalized COVID-19 patients. In addition, the detected AMR rates were compared with the AMR ratesof the pre-pandemic period.Patients and Methods: The isolates grown in respiratory and blood samples of adult patients hospitalized with the diagnosis ofCOVID-19 between March 2020 and December 2020 were evaluated retrospectively. The same data in hospitalized patients before thepandemic, between March and December 2019, were evaluated retrospectively.Results: A total of 724 samples were included in the study. The superinfection rate was found to be 15.3%. The most frequently isolatedmicroorganisms are; Acinetobacter baumannii (34.4%), Staphylococcus aureus (10.8%), Klebsiella pneumoniae (9.7%) and Pseudomonasaeruginosa (7.3%). The lowest resistance rates in Klebsiella pneumoniae isolates were found for aminoglycosides, in Acinetobacterbaumannii isolates were found for trimethoprim-sulfamethoxazole, in Pseudomonas aeruginosa isolates were found for amikacin.When pre-pandemic and pandemic AMR rates were compared; a significant increase in amikacin resistance was detected only inKlebsiella pneumoniae isolates during the pandemic period (P:0.049).Conclusion: The data we have presented may help clinicians in the selection of antimicrobials for empirical therapy by revealing theeffect of the pandemic on AMR.
KW  - Antimicrobial resistance
KW  - Bacterial infection
KW  - COVID-19
KW  - Fungal infection
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UR  - https://doi.org/10.5472/marumj.1367895
L1  - https://dergipark.org.tr/en/download/article-file/3443327
ER  -