@article{article_1368021, title={Monitoring tissue perfusion during extracorporeal circulation with laser speckle contrast imaging}, journal={Marmara Medical Journal}, volume={36}, pages={339–343}, year={2023}, DOI={10.5472/marumj.1368021}, url={https://izlik.org/JA79FP82RR}, author={Ulugol, Halim and Tosun, Melis and Aksu, Ugur and Erkek, Esin and Guclu, Pinar and Okten, Murat and Toraman, Fevzi}, keywords={Skin perfusion, Laser speckle contrast imaging, Extracorporeal circulation, Coronary artery bypass grafting, Extubation time}, abstract={Objective: The laser speckle contrast imaging (LSCI) system is a method to evaluate microcirculation. The primary aim of our study is to evaluate the relationship between LSCI and perfusion markers in coronary artery bypass grafting (CABG). Our second aim is to investigate the relationship between LSCI and extubation time in the intensive care unit. Patients and Methods: Fifteen patients aged 43-80 years who will undergo on-pump CABG were included in the prospective study. Mean arterial pressure (mmHg), heart rate (min-1), PO2 (mmHg), PCO2 (mmHg) and lactate (mmol/L) levels were measured preinduction, post-induction, 10th minute of the extracorporeal circulation, post-crossclamp, and post-operatively. At the same time points, LSCI values from the skin were measured and recorded. The intubation times of the patients were also recorded. Results: There was no significant change in systemic tissue perfusion markers (P>0.05). LSCI perfusion values decreased significantly from induction and remained low until the end of surgery (P <0.05). The perfusion value (98±11 PU) of the patients who were intubated for less than 8 hours was better than the perfusion value (52±4.8 PU) of the patients who were intubated for more than 8 hours (P <0.05). Conclusion: In our study, a significant change occurred in skin tissue perfusion before systemic perfusion parameters in CABG, and low perfusion was associated with prolonged intubation time.}, number={3}