TY - JOUR T1 - Clinical characteristics of patients with ectopic pregnancies treated with repeated doses of methotrexate. TT - Metotreksat ile tedavi edilen ektopik gebeliklerde tekrarlayan doz kullanılan hastaların klinik özellikleri. AU - Kurtay, Sabri AU - Doğan Yangır, Gamze AU - Gözüküçük, Murat AU - Ustun, Yusuf PY - 2024 DA - August DO - 10.20492/aeahtd.1371505 JF - Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi PB - Sağlık Bakanlığı Ankara Eğitim ve Araştırma Hastanesi WT - DergiPark SN - 1304-6187 SP - 49 EP - 52 VL - 57 IS - 2 LA - en AB - ABSTRACTAim: Dose regimens of methotrexate used in the medical treatment of ectopic pregnancy vary. In this study, factors determining single-dose and repeated-dose methotrexate regimens were investigated.Material and methods: Patients diagnosed with ectopic pregnancy and treated with methotrexate in a tertiary care center were retrospectively analyzed. Medical characteristics, ultrasonography findings, and laboratory values of patients treated with single-dose methotrexate (n=128) and patients treated with additional doses (n=30) were compared. p KW - Beta-human chorionic gonadotropin KW - Ectopic pregnancy KW - Methotrexate N2 - Amaç: Ektopik gebeliğin medikal tedavisinde kullanılan metotreksatın uygulama rejimleri farklılık göstermektedir. Bu çalışmada tek doz ve tekrarlayan doz metotreksat rejimlerini belirleyen faktörler araştırılmıştır.Gereç ve Yöntem: 3. basamak bir merkezdeki ektopik gebelik tanısı almış ve metotreksat ile tedavi edilmiş hastalar retrospektif olarak incelendi. Tek doz metotreksat ile tedavisi sağlanmış (n=128) ve ek doz uygulanmış (n=30) hastalara ait tıbbi özellikler, ultrasonografi bulguları ve laboratuvar değerleri karşılaştırıldı. p CR - 1. Bouyer J, Coste J, Fernandez H, Pouly JL, Job-Spira N. Sites of ectopic pregnancy: a 10 year population-based study of 1800 cases. 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Day 4 and day 0 neutrophil-to-lymphocyte ratios as predictors of treatment failure with single-dose methotrexate for ectopic pregnancies. Int J Gynaecol Obstet. 2024;165(1):131-137. doi: 10.1002/ijgo.15248 UR - https://doi.org/10.20492/aeahtd.1371505 L1 - https://dergipark.org.tr/en/download/article-file/3455440 ER -