TY - JOUR T1 - The effect of scaling and root planing on salivary cortisol levels in patients with moderate chronic periodontitis AU - Halalkhor, Sohrab AU - Abootalebzadeh, Mozhgan AU - Fereidooni, Majid AU - Qujeq, Durdi AU - Khosravi, Mahmood AU - Neamati, Nahid AU - Gholinia, Hemmat PY - 2024 DA - May Y2 - 2024 JF - Deneysel ve Klinik Tıp Dergisi JO - J. Exp. Clin. Med. PB - Ondokuz Mayıs University WT - DergiPark SN - 1309-4483 SP - 253 EP - 258 VL - 41 IS - 2 LA - en AB - Periodontitis is known as one of the most prevalent inflammatory oral diseases. Glucocorticoid hormones such as cortisol, produced by the hypothalamus–pituitary–adrenal axis can influence all processes and tissues in human body homeostasis. Typically, the glucocorticoids have been regarded as anti-inflammatory substances and have pro-inflammatory effect in the body. The aim of this study was to evaluate the effect of non-surgical periodontal treatment (NPT) on cortisol levels in patients with moderate chronic periodontitis (MCP). Saliva samples were collected from 42 participants with MCP before and two months after scaling and root planing (SRP). Salivary cortisol levels (SCLs) were measured by electrochemiluminescence immunoassay method. The relationship between clinical periodontal parameters such as gingival index (GI) and probing pocket depth (PPD) with cortisol levels was assessed and analyzed by statistical analysis. was statistically analyzed The SCLs were significantly lower after treatment than before treatment (p=0.02). The GI and PPD showed significant differences (p KW - Glucocorticoid KW - Cortisol KW - Scaling and root planing KW - Chronic periodontitis KW - Saliva CR - Botelho J, Machado V, Mascarenhas P, Rua J, Alves R, Cavacas MA, et al. 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