TY - JOUR T1 - Maternal Aneminin Perinatal Sonuçlara Etkisinin Değerlendirilmesi TT - Evaluation of the Effect of Maternal Anemia on Perinatal Outcomes AU - Adak, İbrahim Halil AU - Barut, Mert Ulaş AU - Sak, Sibel PY - 2024 DA - April Y2 - 2024 DO - 10.35440/hutfd.1393767 JF - Harran Üniversitesi Tıp Fakültesi Dergisi PB - Harran University WT - DergiPark SN - 1304-9623 SP - 73 EP - 77 VL - 21 IS - 1 LA - tr AB - Amaç: Çalışmamızın amacı Harran Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum kliniğinde son 1 yılda yatan ve doğum yapan gebelerde Maternal Aneminin Perinatal Sonuçlara etkisinin değerlendirilmesidir.Gereç ve Yöntemler: Çalışmaya 1 Ocak 2021 – 31 Aralık 2021 arasında Harran Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum kliniğine yatan ve doğum yapan gebeler dahil edildi. Bu gebelerin bilgileri retrospektif olarak değerlendirildi. Çalışma grubu, doğum için başvuru esnasında hemog¬lobin düzeyi ile 3. trimesterda bakılmış hemoglobin düzeyi <11 g/dl olan gebelerden oluşturuldu. Kontrol grubu ise aynı tarih aralığında doğum yapan, doğumda ve 3. trimesterda hemoglobin düzeyi 11 g/dl ve üzerinde olan ve sistemik hastalığı olmayan gebeler tarafından oluşturuldu. Hastalar randomize seçildi. Gruplar obstetrik ve perinatal sonuçlar açısından karşılaştırıldı. Bulgular: Bu araştırmaya 50 gebe çalışma grubu olarak ve 50 gebe de kontrol grubu olmak üzere toplam 100 gebe dahil edildi. Gruplar arasında düşük doğum ağırlığı, normal doğum ağırlığı, intrauterin gelişme kısıtlılığı oranları, bebeklerin 1. ve 5. dakika apgar skorları, yenidoğan servisine yatış oranları açısından istatistiksel olarak anlamlı bir farklılık saptanmadı (p>0,05). Anemik grupta preterm doğum, oranı istatistiksel olarak kontrol grubuyla anlamlı derecede yüksek bulundu. (%34 vs %14, p=0,020), Sonuç: Çalışmamızda elde edilen verilere göre gebelerde Anemik grupta preterm doğum, oranı istatistiksel olarak kontrol grubundan anlamlı yüksek bulundu. KW - Gebelik KW - anemi KW - perinatal sonuçlar N2 - Background: To evaluate the effect of Maternal Anemia on Perinatal Outcomes in pregnant women who were hospitalized and delivered in Harran University Faculty of Medicine Gynecology and Ob-stetrics clinic in the last 1 year.Materials and Methods: The current study included pregnant women who were hospitalized and delivered in Harran University Faculty of Medicine, Department of Obstetrics and Gynecology be-tween January 1, 2021 and December 31, 2021. The information of these pregnant women was analyzed retrospectively. In the study group, the hemog¬lobin value of the patients at the time of admission for delivery and the hemog¬lobin value in the 3rd trimester was determined to be lower than 11 g/dl. The control group consisted of pregnant women who gave birth between the same dates, had a hemoglobin value of 11 g/dl or higher at delivery and in the 3rd trimester and had no systemic disease. Patients were randomly selected. The groups were compared in terms of obstetric and perinatal outcomes.Results: A total of 100 pregnant women were included in this study with 50 pregnant women as the study group and 50 pregnant women as the control group. There was no difference between the groups in the rates of intrauterine growth retardation, normal and low birth weight babies, Apgar scores at 1 minute and 5 minutes, and hospitalization in the neonatal ward (p>0.05). The preterm delivery rate was higher in the anemia group compared to the control group (34% vs 14%, p=0.020).Conclusions: According to the data obtained in this study, the preterm delivery rate of the anemic group was statistically significantly higher than the control group.Key Words: Anemia Pregnancy, perinatal outcomes, New-born CR - 1. WHO recommendations on antenatal care for a positive pregnancy experience. WorldHealth Organization; Luxembo-urg, 2016. 11-13. CR - 2. Pavord S, Daru J, Prasannan N, et al. UK guidelines on the management of iron deficiency in pregnancy. Br J Haematol 2020; 188:819. CR - 3. American College of Obstetricians and Gynecologists' Com-mittee on Practice Bulletins—Obstetrics. Anemia in Preg-nancy: ACOG 2021; 138:55-64. CR - 4. Ruiz de Viñaspre-Hernández R, Gea-Caballero V, Juárez-Vela R, Iruzubieta-Barragán FJ. The definition, screening, and tre-atment of postpartum anemia: A systematic review of guide-lines. Birth 2021; 48:14-. CR - 5. McLean E, Cogswell M, Egli I, Wojdyla D, de Benoist B. Worldwide prevalence of anaemia, WHO Vitamin and Mine-ral Nutrition Information System, 1993-2005. Public Health Nutr. 2009; 12(4):444-454. CR - 6. Reveiz L, Gyte GM, Cuervo LG, Casasbuenas A. Treatments for iron-deficiency anaemia in pregnancy. Cochrane Database Syst Rev 2011; :CD003094. CR - 7. http://www.who.int/elena/titles/intermittent_iron_pregnancy_malaria/en/ (Accessed on February 08, 2018). CR - 8. World Health Organization. Preconception care to reduce maternal and childhood mortality and morbidity. WHO HQ; Geneva, 2013. CR - 9. Prevalence of anaemia in pregnant women: Estimates by WHO region. Global Health Observatory data repository. World Health Organization (WHO). Available at: https://apps.who.int/gho/data/view.main.ANAEMIAWOMENPWREG (Accessed on May 02, 2023). CR - 10. Sak ME, Özkul Ö, Evsen MS, Sak S, Evliyaoğlu O: Gebelik Anemisinin Perinatal Sonuçlara Etkisi. Dicle Tıp Dergisi 2009:36 (1):39-42. CR - 11. Rasmussen KM: Is There a Causal Relationship between Iron Deficiency or Iron-Deficiency Anemia and Weight at Birth, Length of Gestation and Perinatal Mortality? The Journal of Nutrition. 2001; 131(2): 590–603 CR - 12. Lone FW, Qureshi BN ,Emanuel F: Maternal anaemia and its impact on perinatal outcome: Tropical Medicine and Interna-tional Health. 2004; 9(4): 486–490. CR - 13. UJ Bakhtiar, Y Khan, R Nasar : Relationship between mater-nal hemoglobin and perinatal outcome. RMJ. 2007; 32(2): 102-104. CR - 14. Fleming AF: A Study of Anemia of Pregnancy in Ibadan, Wes-tern Nigeria with Special Reference to Folic Acid Deficieny. MD Thesis, University of Cambridge. 1991 Quoted by A. Hug-hes in ‘ Anemia of Pregnancy’ Maternal Health and Safe Mot-herhood, WHO,1991. CR - 15. Levy A, Fraser D, Katz M, Mazor M, Sheiner E. Maternal anemia during pregnancy is an independent risk factor for low birthweight and preterm delivery. Eur J Obstet Gynecol Rep-rod Biol 2005;122:182-186. CR - 16. Lao TT, Pun TC: Anemia in pregnancy-is the current definition meaning- ful? Eur J Obstet Gynecol Reprod Biol 1996;68:53-8 CR - 17. Working group on infant growth. An evaluation of infant growth; the issue and interpretation of anthropometry in in-fants. WHO Bull. 1995;73:165- 174. CR - 18. Diet, nutrition, and the prevention of chronic diseases. Report of a WHO Study Group. World Health Organ Tech Rep Ser. 1990;797:1-204. CR - 19. Steer P,Alam Ash M, Wadsworth J, Welch A. Relation between maternal hemoglobin concentration and birth we-ight in different ethnic groups. Br Med J 1995;310:489-491. CR - 20. Schwartz WJ, Thurnau GR. Iron deficieny anemia in preg-nancy. Clin Obs¬tet Gynecol 1995;38(3):443-454. CR - 21. Murphy JF, O Riordan J, Newcombe RG, Coles EC, Pearson JF. Relation of hemoglobin levels in first and second trimasters to outcome of pregnan¬cy. Lancet 1986;1(8488):992-995. CR - 22. Xiong X, Buekens P, Alexander S, Demianczuk N, Wollast E. Anemia during pregnancy and birth outcome: A meta-analysis. Am J Perina¬tol. 2000;17(3):137-146. CR - 23. Malhotra M, Sharma JB, Batra S, SharmaS, Murthy NS, Arora R. Maternal and perinatal outcome in varying degrees of anemia. Int J Gynaecol Obs¬tet 2002;79:93-100. CR - 24. Uçkan K, Çeleğen İ, Uçkan T. Gebelik Anemisinin Perinatal Sonuçlara Etkisinin Değerlendirilmesi. Kafkas Journal of Medi-cal Sciences. 2020;10:131–135. UR - https://doi.org/10.35440/hutfd.1393767 L1 - https://dergipark.org.tr/en/download/article-file/3550028 ER -