TY - JOUR T1 - Dıabetic Foot: Wound Healing, Amputation Decision, and Innovative Developments AU - Kapukaya, Rana AU - Bozkurt, Mehmet PY - 2024 DA - March Y2 - 2024 DO - 10.36516/jocass.1404365 JF - Journal of Cukurova Anesthesia and Surgical Sciences JO - J Cukurova Anesth Surg PB - Merthan TUNAY WT - DergiPark SN - 2667-498X SP - 23 EP - 26 VL - 7 IS - 1 LA - en AB - Aim: To review the effects of diabetes-related diseases on the healing process and amputation decision in diabetic foot ulcers (DFU), negative pressure wound therapy (NPWT) results, and current treatment approaches.Materials and Methods: The study was planned as retrospective and cross-sectional. Data of patients who were admitted to our clinic due to DFU and were treated were examined. A total of 38 patients were included in the study. The results of patients (n=19) who underwent periodic debridement and classic dressing were compared with the results of patients (n=19) who underwent NPWT. Healing in patients was achieved by amputation (n=8), repair with partial thickness grafts or flaps (n=10), and secondary epithelialization development (n=10). The effect of diabetes-related peripheral arterial disease (PAD), cardiovascular disease (CVD), chronic kidney disease (CKD), diabetic retinopathy (DRP), and previous amputation history (AH) on recovery time was examined. The predictive importance of diabetes-related diseases for amputation was investigated.Results: It was determined that diabetes-related diseases caused a delay in wound healing. [PAD (p KW - diabetic foot ulcer KW - wound healing KW - amputation KW - diabetes-related diseases CR - 1.Chen L, Sun S, Gao Y, Ran X. Global mortality of diabetic foot ulcer: a sys-tematic review and meta-analysis of observational studies. Diabetes Obes Metab. 20 August 2022 [Epub ahead of print]. https://doi.org/10.1111/dom.14840 CR - 2.Armstrong DG, Swerdlow MA, Armstrong AA, Conte MS, Padula WV, Bus SA. 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Advanced Biomaterials and Topical Medi-cations for Treating Diabetic Foot Ulcers: A Systematic Review and Net-work Meta-Analysis.Advances in Wound Care. http://doi.org/10.1089/wound.2023.0024 CR - 15.Topuz S, Ciger A, Isler A, Alkan M. Effects of negative pressure wound therapy on graft success in patients with diabetic foot ulcers: A retrospec-tive study. Ann Med Res. 2023;30(8):846–50. CR - 16.Quacinella MA, Yong TM, Obremskey WT, Stinner DJ. Negative pressure wound therapy: Where are we in 2022? OTA Int. 2023;11:e247. CR - 17.Kapukaya, R, Ciloglu, O. Treatment of chronic wounds with polyure-thane sponges impregnated with boric acid particles: A randomised con-trolled trial. Int Wound J. 2020; 17: 1159–1165. https://doi.org/10.1111/iwj.13463 UR - https://doi.org/10.36516/jocass.1404365 L1 - https://dergipark.org.tr/en/download/article-file/3597281 ER -