TY - JOUR T1 - Conservative management of cervical ectopic pregnancy: A case report and review of literature AU - Çağlayan, Emel AU - Üstün, Batuhan PY - 2024 DA - May Y2 - 2024 JF - Deneysel ve Klinik Tıp Dergisi JO - J. Exp. Clin. Med. PB - Ondokuz Mayıs University WT - DergiPark SN - 1309-4483 SP - 446 EP - 449 VL - 41 IS - 2 LA - en AB - Ectopic pregnancies, occurring in approximately 1-2% of cases, are typically found within the fallopian tube. Among these instances, cervical ectopic pregnancies constitute less than 1% of cases, with the majority observed within the endocervical canal. This study presents a case of cervical ectopic pregnancy following in vitro fertilization (IVF), treated with a single dose of methotrexate. A 23-year-old woman who has been married for 4 years with a history of infertility presents with complaints of abdominal pain for 2 days and vaginal spotting as bleeding, following her last menstrual period, at 5 weeks and 3 days of pregnancy. In her medical history, the patient mentions having low ovarian reserve (AMH 6.73 pmol/L), which led to in vitro fertilization (IVF) transfer 22 days ago. Due to the patient's young age and it being her first pregnancy, medical treatment with methotrexate (MTX) was decided. MTX was administered at a dose of 50 mg/m² (100 mg of intravenous MTX in 100 ml of 0.9% NaCl). Experiences in cervical ectopic pregnancies predominantly stem from case-based experiences. Thus, when planning treatment for cervical ectopic pregnancy, a conservative or minimally invasive approach may be more appropriate, tailored to the patient's characteristics whenever possible. KW - Cervical KW - ectopic KW - pregnancy KW - methothrexate KW - medical KW - treatment CR - Kraemer B, Abele H, Hahn M, Wallwiener D, Rajab TK, Hornung R. Cervical ectopic pregnancy on the portio: conservative case management and clinical review. Fertil Steril. 2008;90(5):2011.e1-4. doi:10.1016/j.fertnstert.2008.06.018 CR - Tanos V, ElAkhras S, Kaya B. Hysteroscopic management of cervical pregnancy: Case series and review of the literature. J Gynecol Obstet Hum Reprod. 2019;48(4):247-253. doi:10.1016/j.jogoh.2018.05.001 CR - Sheng S, Zhang H, Pan Z, Li T, Wang H, Shi M, Wang F. Treatment of heterotopic cervical pregnancy by ultrasound-guided hysteroscopy: a case report and literature review. Medicine (Baltimore). 2022;101(48):e32177. doi:10.1097/MD.0000000000032177 CR - Javedani Masroor M, Zarei A, Sheibani H. Conservative Management of Cervical Pregnancy with the Administration of Methotrexate and Potassium Chloride: A Case Report. Case Rep Obstet Gynecol. 2022:1352868. doi:10.1155/2022/1352868 CR - Coulter-Nile S, Balachandar K, Ward H. A diagnostic dilemma of an 18-week cervical ectopic pregnancy: A case report. Case Rep Womens Health. 2022;13:33:e00385. doi:10.1016/j.crwh.2022.e00385 CR - Fouda A, Enayat A, Ahmed WE. Conservative management of a viable cervical ectopic pregnancy with systemic and multiple local methotrexate injections: A case report. Eur J Contracept Health Care. 2022;27(3):265-268. doi:10.1080/13625187.2022.2026325 CR - Stabile G, Mangino FP, Romano F, Zinicola G, Ricci G. Ectopic Cervical Pregnancy: Treatment Route. Medicina (Kaunas). 2020;56(6):293. doi:10.3390/medicina56060293 CR - Guzowski G, Sieroszewski P. Invasive ultrasound in the management of cervical ectopic pregnancy. Eur J Obstet Gynecol Reprod Biol. 2014;172:7-9. doi:10.10.16/j.ejogrb.2013.10.016 CR - Mori KH, Tavares BV, Yela DA, Baccaro LFC, Juliato CRT. Experience of a Tertiary Service in the Treatment of Women with Cervical Pregnancy. Rev Bras Ginecol Obstet. 2022;44(11):1014-1020. doi:10.1055/s-0042-175954 CR - Mininni C, Garibaldi S, Fornari L, Domenici L, Cattani R, Bottone P. Effective combined treatment in ectopic cervical pregnancy preserving fertility: a case report and literature review. Eur Rev Med Pharmacol Sci. 2012;25(12):4190-4197. doi:10.2635/eurrev_202106_26121. UR - https://dergipark.org.tr/en/pub/omujecm/issue//1438991 L1 - https://dergipark.org.tr/en/download/article-file/3737044 ER -