@article{article_1451324, title={Evaluation of Stem Cell Applications in Periodontal Regenerative Therapy: A Current Perspective Between 2003-2022}, journal={Van Diş Hekimliği Dergisi}, volume={5}, pages={12–23}, year={2024}, author={Altıkat, Kadriye Merve and Töre, Efe}, keywords={Cell transplantation, mesenchymal stem cells, periodontal treatment, tissue engineering}, abstract={The periodontium comprises the fundamental tissues of the tooth, namely the gingiva, periodontal ligament, cementum, and alveolar bone. Prolonged accumulation of microbial dental plaque on the tooth and gingival margin leads to pathological changes in the periodontal tissues. However, the mechanical and regenerative techniques employed to address the breakdown of periodontal tissue have been unsuccessful in fully restoring the periodontium to its original, disease-free condition. The growing understanding and recognition of the potential uses of stem cell therapy have led to the emergence of new perspectives on periodontal regeneration approaches. This review investigates mesenchymal stem cells and their use in periodontal regeneration treatment.}, number={1}, publisher={Van Yuzuncu Yıl University}