TY - JOUR T1 - Evaluation of the Association of Serum Uric Acid Levels and Stroke in Emergency Department Patients TT - Acil Servis Hastalarında Serum Ürik Asit Düzeyi ve İnme İlişkisinin Değerlendirilmesi AU - Şengüldür, Erdinç AU - Demir, Mehmet Cihat PY - 2024 DA - August Y2 - 2024 DO - 10.18678/dtfd.1457023 JF - Duzce Medical Journal JO - Duzce Med J PB - Duzce University WT - DergiPark SN - 1307-671X SP - 112 EP - 117 VL - 26 IS - 2 LA - en AB - Aim: Stroke is a leading cause of disability and fatality. While clinical and imaging methods are commonly used in stroke management, biochemical parameters such as serum uric acid (SUA) level are largely overlooked. This study aimed to examine the relationship between high or low SUA levels and both ischemic and hemorrhagic stroke.Material and Methods: This is a retrospective, single-center observational study. The study included all consecutive patients who were consulted from the emergency department (ED) to neurology and/or neurosurgery between January 1, 2023, and December 31, 2023. Data of the patients were obtained from the hospital computer system and ED records. While SUA levels of ≤2.8 mg/dL indicated hypouricemia, levels of ≥7 mg/dL were considered hyperuricemia.Results: A total of 1186 adult patients were included in the study. It was observed that 484 of them were diagnosed with stroke, 394 were ischemic stroke, and 90 were hemorrhagic stroke. Stroke patients had higher median SUA levels (p KW - Emergency Department KW - Stroke KW - Uric Acid N2 - Amaç: İnme, sakatlık ve ölümlerin önde gelen nedenlerinden biridir. İnme yönetiminde klinik ve görüntüleme yöntemleri yaygın olarak kullanılırken, serum ürik asit (SUA) düzeyi gibi biyokimyasal parametreler büyük ölçüde göz ardı edilmektedir. Bu çalışmada, yüksek veya düşük SUA düzeyleri ile hem iskemik hem de hemorajik inme arasındaki ilişkinin incelenmesi amaçlanmıştır.Gereç ve Yöntemler: Bu çalışma retrospektif, tek merkezli gözlemsel bir çalışmadır. Çalışmaya 1 Ocak 2023 ile 31 Aralık 2023 tarihleri arasında acil servisten nöroloji ve/veya beyin cerrahisine konsülte edilen tüm ardışık hastalar dahil edilmiştir. Hastaların verileri hastane bilgisayar sisteminden ve acil servis kayıtlarından elde edilmiştir. ≤2,8 mg/dL olan SUA düzeyleri hipoürisemiyi gösterirken, ≥7 mg/dL olması hiperürisemi olarak kabul edildi.Bulgular: Çalışmaya toplam 1186 yetişkin hasta dahil edildi. Bunların 484'ünün inme tanısı aldığı, 394'ünün iskemik inme, 90'ının ise hemorajik inme olduğu görüldü. İnme hastalarının medyan SUA düzeyleri daha yüksekti (p CR - GBD 2016 Neurology Collaborators. Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. 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